Organizers:
Robin Williams (Royal Holloway, University of London, UK)
Talvinder Sihra (University College London, UK)
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Session 1
Chair:
Anne Mudge (University College London, UK)
12:30 - 14:00 Registration
14:00 - 14:10 Welcome and introduction from the organizers
Recent genetic findings in bipolar disorder
Nick Craddock - Plenary Speaker (Cardiff University, UK)
Neural network dysfunction in bipolar disorder: clues from the efficacy of lamotrigine
Charles Large (GlaxoSmithKline, Italy)
15:30 - 16:00 Coffee/tea break
Risk and resilience in bipolar disorder
Sophia Frangou (Institute of psychiatry, King's College London, UK)
Chronic lithium treatment leads to altered gene expression in frontal cortex of rats
Seyyed Hossein Fatemi (University of Minnesota, USA)
Diffusion imaging study of the corpus callosum in bipolar disorder
Paolo Brambilla (University of Udine, Italy)
17:30 - 19:00 Drinks reception and poster session
19:00 - 21:00 Conference Dinner at the Picture Gallery
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Session 2
Chair:
Robin Williams (Royal Holloway, University of London, UK)
Cellular consequences of inositol depletion
Miriam Greenberg - Plenary Speaker (Wayne State University, USA)
Is the brain arachidonic acid cascade a common target of mood stabilizers?
Richard Bazinet (University of Toronto, Canada)
PLA2 function in Dictyostelium: using a simple model organism to elucidate the changes in lipid metabolism upon VPA treatment
Selected oral communication - Nadine Pawolleck (Royal Holloway, University of London, UK)
10:40 - 11:00 Coffee/tea break
PI(3,4,5)P3 as a cellular target of mood stabilizers
Adrian Harwood (Cardiff University, UK)
Development of the first drug-like inhibitor for inositol monophosphatase
Selected oral communication - Sridhar Vasudevan (University of Oxford, UK)
Valproic acid and LiCl sensitivity in prs mutants of Saccharomyces cerevisiae
Michael Schweizer (Heriot-Watt University, Edinburgh, UK)
Post-natal triggering of bipolar episodes and implications for understanding bipolar illness
Ian Jones (Cardiff University, UK)
Maternal infanticide in the pig: a genetic model for puerperal psychosis?
Selected oral communication - Claire Quilter (University of Cambridge, UK)
13:10 - 14:00 Lunch and poster viewing
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Session 3
Chair:
Michael Berridge (The Babraham Institute, Cambridge, UK)
Inositol in bipolar disorder and its treatment: update 2009
Galila Agam (Ben-Gurion University of the Negev, Israel)
Phosphoinositide signalling as the therapeutic target of valproic acid
Robin Williams (Royal Holloway, University of London, UK)
Investigation of the H+/myo-inositol transporter (HMIT) as a neuronal regulator of phosphoinositide signalling
Selected oral communication - Elena Di Daniel (GlaxoSmithKline, UK)
Identification of peripheral biomarkers associated with the inflammatory component of bipolar disorder
Selected oral communication - Marlis Herberth (University of Cambridge, UK)
15:40 - 16:10 Coffee/tea break
Serum BDNF levels in euthymic bipolar disorder: preliminary results from the galway bipolar study
Selected oral communication - Camilla Langan (National University of Ireland Galway, Ireland)
GSK3 as a direct target of lithium
Peter Klein - Plenary Speaker (University of Pennsylvania School of Medicine, USA)
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