|
15 December 2008 Poster Session 1: 17:30-19:30
P001 Translational re-programming following UVB irradiation is mediated by DNA-PKCS and allows selective synthesis of mRNAs encoding DNA repair enzymes
A. Kondrashov, I.R. Powley, L.A. Young, H.C. Dobbyn, K. Hill, M. Stoneley, G.C.M. Smith, C. Hayes, T.W. Gant, K.A. Spriggs, M. Bushell and A.E. Willis
P003 Precise repair of IES excision sites in Paramecium is mediated by the Non Homologous End-Joining pathway (NHEJ)
A. Kapusta, J. Nowack, L. Sperling, M. Bétermier, S. Malinsky, E. Meyer, A. Matsuda and J. Forney
P005 Nesprin-2 associates with PML NBs to mediate DNA damage repair and safeguard genomic integrity
D. Warren, T. Tajsic, R. Searles, Q. Zhang and C. Shanahan
P007 The gene mutated in the RIDDLE syndrome regulates a ubiquitin-dependent signalling cascade at sites of DNA damage
G.S. Stewart, S. Panier, K. Townsend, A.K. Al-Hakim, N.K. Kolas, E.S. Miller, S. Nakada, J. Ylanko, C. Oldreive, S. Olivarius, M. Mendez, A. Tagliaferro, L. Pelletier, N. Taubenheim, A. Durandy, P.J. Byrd, T. Stankovic, A.M.R. Taylor and D. Durocher
P009 Hierarchy of non-homologous end-joining, single-strand-annealing and gene conversion at site-directed DNA double-strand breaks
W.Y. Mansour, H. Willers and J. Dahm-Daphi
P011 DNA damage and histological changes in hepatocarcinogenesis rats treated with Neem extract
P. Hanachi and O. Fauziah
P013 ATM activation and signalling under hypoxic conditions
E.M. Hammond
P015 Chromosomal instability associated with chromosomal translocation in women with recurrent abortions
M. Alkhalaf
P017 High content analysis of gH2AX foci by confocal 3D microscopy
O.T. Davies, C. Bruce, B. Kysela, R.E. Palmer and R.A. Meldrum
P019 The C-terminus of Brca2 links the disassembly of Rad51 complexes to the timing of mitotic entry
N. Ayoub, E. Rajendra, X. Su, A.D. Jeyasekharan, R. Mahen and A.R. Venkitaraman
P021 The structure and function of the archaeal XPD DNA helicase explain the phenotypes of xpd mutations in human
J. Rudolf, C. Rouillon, A.-M. McRobbies and M. White
P023 Quantification of repair of localised oxidative damage in live cells induced by focused near infra-red multiphoton absorption: direct evidence that the polymorphic variant [Cys326] of OGG1 is repair deficient
A.E. Zielinska, R.A. Meldrum and N.J. Hodges
P025 Development of a novel technique to quantify activity and localisation of the base excision repair protein OGG1 in individual cells and its induction by the pro-oxidant potassium bromate
L. Mirbahai, R.M. Kershaw, R.A. Meldrum and N.J. Hodges
P027 Sae2/CtIP-dependent regulation of DNA resection during the cell cycle
P. Huertas and S.P. Jackson
P029 Mre11 modulates the fidelity of telomere fusion events in human cells
M. Tankimanova, R. Capper, B.T. Letsolo, J. Rowson and D.M. Baird
P031 Assembly of a clamp loading, AAA+ motor: the g-complex controls the d wrench
A.Y. Park, B. Rutolo, D. Barsky, S. Jergic, M. O’Donnell, N.E. Dixon and C.V. Robinson
P033 Defective DNA ligation during chromosomal short-patch single-strand break repair in ataxia oculomotor apraxia-1
J.J. Reynolds, S.F. El-Khamisy, S. Katyal, P. Clements, P.J. McKinnon and K.W. Caldecott
P035 Image-based screening to characterise cell-signaling networks responsible for retinoblastoma protein activation in response to ionising radiation
E. Runnacles, S. Mittnacht, S. Stockwell and W. Aherne
P037 The effect of estrogen receptor status and RAD51 overexpression on tumor progression
H. Hwang, T. Hsu and E. Brown
P039 How does RNA Polymerase I relay DNA damage-induced apoptosis in C. elegans?
R. Eberhard, L. Stergiou, R. Hofmann and M. Hengartner
P041 The interaction of a new ciprofloxacin ruthenium(III) complex with DNA: a preliminary study
V. Uivarosi, V. Aldea and D. Iacob
P043 Structure of the human RECQ1 DNA helicase
O. Gileadi, B. Shrestha, N. Burgess-Brown, A. Pike, O. King, F. Niesen, Y. Zhang, L. Muzzolini, V. Popuri, S. Costantini and A. Vindigni
P045 RAD51C functions downstream of RPA in checkpoint signalling
S. Badie, M. Thanasoula, C. Liao, P. Barber and M. Tarsounas
P047 Mass spectrometric screening for quadruplex DNA-selective ligands
K.C. Gornall, J.B. Bremner, M.J. Kelso and J.L. Beck
P049 C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis
S. Greiss, J. Hall, S. Ahmed and A. Gartner
P051 Development of a kinase assay for high-throughput screening of DNA-PK inhibitors
I. Yakymovych, B. Mörk, D. Zong, P. Hååg, R. Lewensohn and K. Viktorsson
P053 Local responses to DNA damage in human cells: focus on chromatin remodeling factors
S.E. Polo, A. Kaidi and S.P. Jackson
P055 The role of human Snm1A in DNA interstrand cross-link repair
A.T. Wang, E.L. Cattell, A. Hazrati, M. Ramis-Castelltort, J.A. Hartley and P.J. McHugh
P059 Constitutive phosphorylation of MDC1 physically links the MRE11–RAD50–NBS1 complex to damaged chromatin
C. Spycher, E.S. Miller, K. Townsend, L. Pavic, N.A. Morrice, P. Janscak, G.S. Stewart and M. Stucki
P063 Study of human BRCA2 expression in Saccharomyces cerevisiae
G. Millot, V. Lejour, J. Galipon, A. Lescure, J. Lopes and A. Nicola
P065 Inhibition of DNA double strand repair by trifluoperazine mediates chemosensitization through enhanced activation of stress-induced mitochondrial apoptotic pathway
D. Zong, P. Hååg, I. Yakymovych, L. Stenke, R. Lewensohn and K. Viktorsson
P067 GEN-1 Holliday Junction resolvase acts in a non-canonical DNA damage checkpoint pathway
A. Bailly, S. Ip, J. Boerckel, S. Ahmed, S. West and A. Gartner
P069 Rapid chromatin immunoprecipitation from a low number of cells with LowCell# ChIP kit
J. Magdalena and J. Frampton
P071 A genome-wide screen for sensitivity or resistance to the G quadruplex binding porphyrin TMPyP4 in budding yeast
S. Merchan, S. Addinall, C. Lawless, D. Wilkinson, J. Dewar and D. Lydall
P073 Replication and repair crosstalk induced by targeted DNA damage
R.A. Meldrum, R.E. Palmer and O.T. Davies
P075 Protective potential of hydroxy-cinnamic acid derivative natural antioxidants from Euphorbia hirta against DNA oxidation
N. Kumar Sharma and R. Prasad
P077 The role of ubiquitination in DNA damage response: proteomic analysis to identify new DNA-damage induced ubiquitinated proteins
J. Selvarajah and A. Moumen
P079 Nucleotide excision repair - from recognition to incision
H.M. Roth and C. Kisker
|
|
16 December 2008 Poster Session 2: 12:30-14:30
P002 Oxidative DNA damage and DNA repair in sporadic Amyotrophic Lateral Sclerosis
F. Coppedè, M.R. D’Errico, A. Lo Gerfo, M. Mancuso, R. del Bo, G.P. Comi, L. Murri, L. Migliore and G. Siciliano
P004 Altered function p53 missense mutations associated with breast cancers
J. Jordan, A. Inga, K. Conway, L. Carey and M.A. Resnick
P006 Dephosphorylation of tyrosine-phosphorylated H2AX regulates apoptosis and cell survival decisions
P.J. Cook, B.G. Ju, F. Telese, X. Wang, C.K. Glass and M.G. Rosenfeld
P008 Single molecule studies on the DNA damage removal complex UvrBC of the nucleotide excision repair machinery
I. Tessmer and C. Kisker
P010 Recombination at DNA replication fork barriers is not universal and is differentially regulated by Swi1
D.W. Pryce, S. Ramayah and R.J. McFarlane
P012 Direct visualization of DSB induction and repair in gene dense (RIDGE) and gene poor (anti-RIDGE) chromatin domains
M. Falk, E. Lukasova and S. Kozubek
P014 Understanding the interplay between recombinases, helicases and DNA binding proteins during homologous recombination in Archaea
A. McRobbie and M.F. White
P016 FEN endonuclease and exonuclease activities are rate limited by different steps
B. Sengerová, R. Williams and J.A. Grasby
P018 Damaged-oligonucleotides biochip : a convenient means to assess the DNA repair ability of any biological sample
B. Pons, A.-S. Belmont, A. Forestier, V. Chapuis, S. Caillat and S. Sauvaigo
P020 The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo
L. Malivert, I. Callebaut, P. Rivera-Munoz, A. Fischer, J.-P. Mornon, P. Revy and J.-P. de Villartay
P022 Three metal ions participate in the reaction catalysed by T5FEN
K. Syson, C. Tomlinson and J. Grasby
P024 Crystal structure of the FeS cluster-containing nucleotide excision repair helicase XPD
S. Wolski, J. Kuper and C. Kisker
P026 Processing of complex DSB by BER and end joining proteins
M.E. Lomax, T.A. Dobbs, P. Palmer, E. Jagielska and P. O’Neill
P028 Studies of the gap endonucelase activity of flap endonuclease
A. Beddows, B. Sengerovà and J. Grasby
P030 Aspirin regulation of DNA repair gene expression in colorectal cancer
H.K. Dibra, J.E.P. Brown, P. Hooley and I.D. Nicholl
P032 Distinct effects of DNA-PKcs and Artemis inactivation on blunt DNA ends repair in vivo
S.M. Candéias, C. Couedel, P. Soulas, R. Couderc, M. Jasin, J.-P. de Villartay, P.N. Marche, E. Jouvin-Marche and C. Touvrey
P034 Intra -S- DNA damage checkpoint mediated by the spindle assembly factor TPX2
G. Neumayer, J. Wang, S.Y. Shim, H.C. Tran and M.D. Nguyen
P036 Different mechanisms of DNA damage checkpoint induction in response to telomere dysfunction in adult stem cells compared to fibroblasts
N.R. Kodandaramireddy, A. Lechel, R.A. Choudhury, A. Gompf, J. Zhenyu and K.L. Rudolph
P038 TRP53 protects against accumulation of damaged cells and organ dysfunction in telomere dysfunctional mice
Y. Begus-Nahrmann and K.L. Rudolph
P040 Using the S. cerevisiae sgs1 mutant as a model system to investigate Bloom’s syndrome
H.W. Mankouri, H.-P. Ngo and I.D. Hickson
P042 Molecular interplay between UvrA and UvrB in NER
J. Kuper, H. Roth and C. Kisker
P044 Sensitization of hypoxic tumour cells through inhibition of PRP is oxygen dependent and correlates with decreased homologous recombination
Z. Bencokova, I. Pires, P. Gottipati, T. Helleday and E. Hammond
P046 Mass spectrometric analysis of competition among metallointercalators and PU.1 transcription factor for DNA
J. Talib, C.D. Nguyen, J.R. Aldrich-Wright, J. Mackay, S.F. Ralph and J.L. Beck
P048 Analysis of DNA repair in living cells
O. Mortusewicz and H. Leonhardt
P050 Translational reprogramming following DNA damage
L.A. Young, G.C.M. Smith, M. Bushell and A.E. Willis
P052 Cell biological studies of RNA helicase A and WRN helicase
C. Köhler, H. Pospiech and F. Große
P054 Electrochemical assay for p53-DNA interactions using immunoprecipitation at magnetic beads
K. Nemcová, L. Havran, P. Šebest, H. Pivon ková, P. Horáková, H. Cahová, M. Hocek and M. Fojta
P056 S-adenosylmethionine and DNA damage: sophisticated agent of metabolism
W.A.M. Loenen
P058 Human MDC1 regulates the metaphase-to-anaphase transition
K. Townsend, H. Dyson, A.N. Blackford, E.S. Miller, G.G. Sedgwick, G. Barone, A.S. Turnell and G.S. Stewart
P060 Novel function for 53BP1 as a transcriptional regulator
H. Dyson, K. Townsend, E.S. Miller, J. O’Neil, E.D. Marston, C.M. McConville, M. Hubank, N.D. Perkins and G.S. Stewart
P062 Analysis of NHEJ signaling after GO-treatment in AML
P. Hååg, M. Lagergren Lindberg, L. Kanter, R. Lewensohn, K. Viktorsson and L. Stenke
P064 Monitoring small molecule impact on cell repair capability using lesion containing oligonucleotide microarrays
A.-S. Belmont, B. Pons, S. Caillat and S. Sauvaigo
P066 Cells from Cockayne syndrome patients with classical symptoms of accelerated aging and neurodegeneration show a deficiency in the repair of oxidative DNA damage
D.M. Leach and A.J. Rainbow
P068 Development of human apurinic/apyrimidinic endonuclease (APE1) inhibitors for cancer therapy
M.Z. Mohammed, C. Laughton, I.D. Hickson and S. Madhusudan
P070 Single-stranded DNA foci generated during DNA repair in E. coli
M. Kohiyama, A. Quessada-Vidal, C. Chamot, M. Radman and I. Matic
P072 A systematic proteomic study of irradiated DNA repair deficient Nbn-mice
M. Digweed, A. Melchers, L. Stöckl, M. Anders, K. Sperling and I. Demuth
P074 Analysis of radiation-induced DNA-damage generated by X-rays
B. Dieriks, W. De Vos and P. Van Oostveldt
P076 Energy transfer, DNA normal modes of vibration, bubbles and damage
F. Torrens and G. Castellano
P078 Differential DNA binding activities of Ku proteins from Streptomyces coelicolor
A.M. Cobb, H.R. Sayer, M. Lavesa-Curto and R.P. Bowater
|