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Poster Session 1 - Thursday 7 January 17:35 - 19:00
P001 Deletion of murine Tau gene increases Tau aggregation in a human mutant Tau transgenic mouse model
Kunie Ando, Karelle Leroy, Zehra Yilmaz, Michèle Authelet, Robert De Decker and Jean-Pierre Brion
P002 NMR spectroscopy of the neuronal Tau protein: normal function and implication in Alzheimer’s disease
Isabelle Landrieu, Laziza Amniai, Isabelle Huvent, Alain Sillen, Nathalie Sibille, Jean-Michel Wieruszeski, Arnaud Leroy, Caroline Smet and Guy Lippens
P003 Regulation of Tau-dependent neurodegeneration by brain selective/SAD kinases
Ceri Lyn-Adams, Kevin Moffat, Calum Sutherland and Bruno G. Frenguelli
P004 Dynamic association of Tau with neuronal membranes is regulated by phosphorylation
A.M. Pooler, A. Usardi, A. Hole and D.P. Hanger
P005 Dendritic spine loss in AD is rather a consequence of Tau pathology than directly related to Aβ-oligomers
Jochen Herms, Tobias Bittner, Steffen Burgold, Gerda Mitteregger, Hans A. Kretzschmar, Frank M. Laferla, Nadine A. Hoffmann and Martin Fuhrmann
P006 Cellular aggregation of a Tau fragment derived from tauopathy brain
S. Wray, A. Seereeram, K. Zschiebsch, J. Bhamra, M.R. Fisher and D.P. Hanger
P007 Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive impairment
Leoni Valerio, Salomon Alina and Kivipelto Miia
P008 Aβ42 immunisation alters Tau pathology in Alzheimer’s disease
Boche D, Donald J, Holmes C, Neal J, Love S, Zotova E and Nicoll JA
P009 Altered calpain-mediated protein proteolysis is a feature of human tauopathy brain
J. M. Atherton, M. Bondulich, D. P. Hanger and W. Noble
P010 Dendritic spine loss in 3xTg-AD mice identified by long-term in vivo imaging
Tobias Bittner, Martin Fuhrmann, Steffen Burgold, Frank M. LaFerla and Jochen Herms
P011 Haplotype effect on alternative splicing at the MAPT locus
Tara Caffrey, Franziska Denk and Richard Wade-Martins
P012 Drosophila models of human tauopathies indicate that Tau protein toxicity in vivo is mediated by soluble cytosolic phosphorylated forms of the protein
Sébastien Feuillette, Laetitia Miguel, Thierry Frébourg, Dominique Campion and Magalie Lecourtois
P013 Poster withdrawn
N/A
P014 HSP inducing chemicals do not rescue neuronal dysfunction in a Drosophila larval model of tauopathy
Sinadinos. C, Wyttenbach. A and Mudher. AK
P015 Wlds expression delays neurodegeneration in Drosophila models of acute injury and tauopathy
Newman TA, Shaibah H, Mudher A, Goodwin, S and Shepherd D
P016 Immunotherapy targeting Tau
L. Troquier, R. Caillierez, G. Kervoaze, ME. Grosjean, I. Brion, B. Barbot, CA. Maurage, D. Blum, P. Lassalle, M. Hamdane, N. Sergeant and L. Buée
P017 Tau function in Drosophila melanogaster
Talmat-Amar Y, Franco B, Bockaert J, Grau Y and Parmentier ML
P018 Tau protein: much more than a MAP
Audrey Sultan, Fabrice Nesslany, Morvane Colin, Sandrine Humez, Séverine Bégard, Smaïl Talahari, Anne Loyens, Katia Lécolle, Nadège Zommer, Hélène Tran, Zeyni Mansuroglu, Eliette Bonnefoy, Luc Buée and Marie-Christine Galas
P019 Examining the multifaceted role of the lipid bilayer in Tau aggregation
Shana Elbaum, JocelynTraina, and Elizabeth Rhoades
P020 Analysis of Tau phosphorylation changes in response to different routes of insulin application
Ritchie Williamson, Lidy van Aalten, Alison McNeily, Caroline Stewart, David Balfour, Christian Holscher and Calum Sutherland
P021 The role of DYRK1A in the generation of Tau phosphorylation relevant to Down syndrome
A. Seereeram, M. Siemann and D.P. Hanger
P022 Soluble hyper-phosphorylated Tau disrupts the microtubule-binding function of normal Tau in vivo
Catherine M. Cowan and Amritpal Mudher
P023 Characterisation of a ‘P301L’ Tau knock-in mouse: no Tau pathology but changes in axonal transport of mitochondria
Jonathan Gilley, Anjan Seereeram, Suzanne Mosely, Zehra Yilmaz, Jean-Pierre Brion, Diane Hanger, Brian Anderton and Michael Coleman
P024 A forward genetic mosaic screen to identify novel modifiers of tauopathy in Drosophila
Bart Dermaut, Marc Gistelinck and Patrick Callaerts
P025 Aβ exacerbates the neuronal dysfunction caused by human Tau expression in a Drosophila model of Alzheimer’s disease
James Folwell, Catherine M. Cowan, Megan A. Sealey, Kiren K. Ubhi, Hassan Shiabh, Tracey A. Newman, David Shepherd and Amritpal Mudher
P026 Using Drosophila to investigate the kinases producing pathogenic Tau protein in Alzheimer’s disease
Giulia Povellato, Richard Tuxworth and Guy Tear
P027 Glia modulate the effects of Aβ on Tau phosphorylation and neuronal death in vitro
Claire Garwood, Diane P Hanger and Wendy Noble
P028 Stress enhances Tau phosphorylation and neurodegeneration in Alzheimer's disease
Ursula Quitterer and Said AbdAlla
P029 Iron and ferritin modulate Tau levels in Drosophila
Despoina Goniotaki, Stelios Kosmidis and Efthimios M. C. Skoulakis
P030 The Biguanide metformin acts on Tau phosphorylation via mTOR/PP2A signalling
Eva Kickstein, Sybille Krauss, Paul Thornhill, Désirée Rutschow, Raphael Zeller, Melanie Fuchs, Hartmut Glossmann, Rainer Schneider, Calum Sutherland and Susann Schweiger
P031 Tau-dependent dendropathy in mouse models of Alzheimer’s disease – in vivo imaging and ultrastructural analysis
Nadine A. Hoffmann, Tobias Bittner, Steffen Burgold, Frank M. LaFerla, Michel Goedert and Jochen Herms
P032 Effects of long-lasting voluntary exercise in the THY-Tau22 transgenic mouse model of Alzheimer’s disease-like Tau pathology
Francisco-Jose Fernandez-Gomez, Sylvie Burnouf, Karim Belarbi, Cyril Laurent, Audrey Sultan, Marie-Eve Grosjean, Dominique Demeyer, Hélène Obriot, Raphaëlle Caillierez, Marie-Christine Galas, Ingrid Brion, Bérangère Barbot, Sandrine Humez, Nicolas Sergeant, Malika Hamdane, Luc Buée and David Blum
P033 Poster withdrawn
N/A
P034 Chronic stress aggravates insoluble Tau accumulation in P301L-Tau Tg mice: a gender-based study and its implications in human tauopathies
I. Sotiropoulos, K. Cho1, O.F.X. Almeida and A. Takashima
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