|
Poster Session times:
Wednesday 27 May
Poster Session 1, P001–P028 18:30–21:00
Thursday 28 May
Poster Session 2, P029–P056 18:35–21:00
Friday 29 May
Poster Session 3, P057–P083 15:00–17:25
Wednesday 27 May
Poster Session 1, P001–P028 18:30–21:00
P001 Regulation of the proteasome by monoubiquitination of the subunit Rpn10
M. Isasa, E. Katz, E. Alsina, S. Gonzalez, T. Thomson, D. Finley and B. Crosas
P002 Characterization of a novel role of the ubiquitin-protein ligase Rsp5
E. Katz, M. Isasa, W. Kim, S. Gygi and B. Crosas
P003 The assembly pathway of the 19S regulatory particle of the proteasome
M.-B. Barrault, B. Le Tallec, R. Guérois, F. Ochsenbein and A. Peyroche
P004 Chaperone-assisted assembly of the proteasome core particle
A.C. Matias, A.J. Marques, P.C. Ramos and R.J. Dohmen
P005 A family of ubiquitin conjugating enzymes involved in plant cell death regulation senses oxidative signals
K. Eifler, W.-R. Scheible, N. Schlaich, D. Ernst, M. Novatchkova, R. Konrat, M. Garzón and A. Bachmair
P006 The UBA-UIM domains of USP25 regulate the enzyme ubiquitination state and modulate substrate recognition
A. Denuc, A. Bosch-Comas, R. Gonzàlez-Duarte and G. Marfany
P007 Differential Ufd2-binding properties of budding yeast UBL-UBA proteins Rad23 and Dsk2 adds up to their functional diversity
S. Raasi
P008 Versatile use of Tandem Ubiquitin Binding Entities (TUBEs) for the functional characterisation of ubiquitin-regulated macromolecular complexes
R. Hjerpe, F. Aillet, M. Torres-Ramos, F. Lopitz-Otsoa, V. Lang, P. England and M.S. Rodríguez
P009 Crosstalk between SUMO-2/3 and the ubiquitin-proteasome system
J. Schimmel, K.M. Larsen, I. Matic, M. van Hagen, J. Cox, M. Mann, J.S. Andersen and A.C.O. Vertegaal
P010 SIRT1 stabilizes PML through sumoylation and protects against viral infection
M. Campagna, D. Herranz, M.A. Garcia, L. Marcos-Villar, J. González-Santamaría, P. Gallego, S. Gutierrez, M. Collado, M. Serrano, M. Esteban and C. Rivas
P011 Sumoylation modulates Spalt activity
J. Sánchez, A. Talamillo, C. Pérez, F. Lopitz, M. Rodriguez and R. Barrio
P012 SUMO activation as a regulatory step in the conjugation cascade
J. Seguí and L.M. Lois
P013 Efficient protection and isolation of ubiquitylated proteins under native conditions using tandem ubiquitin binding entities
R. Hjerpe, F. Aillet, M. Torres-Ramos, F. Lopitz-Otsoa, V. Lang, P. England and M.S. Rodríguez
P014 THE role of laforin and malin in lafora disease and the regulation of glycogen metabolism
J. Vallès, D. Vílchez, S. Ros, D. Cifuentes, M. García-Rocha and J. Guinovart
P015 Regulation of sorting nexins by the ubiquitin ligase Itch in melanoma cells
C. Baumann, C.K. Lindholm and F. Lévy
P016 Analysis of Lys63-linked polyubiquitination in neurodegeneration
S. Paine, L. Bedford, J.R. Thorpe, R.J. Mayer, J.R. Cavey, N. Bajaj, P.W. Sheppard, J. Lowe and R. Layfield
P017 Proteolytic downregulation of the polyubiquitin receptors in Drosophila melanogaster
Z. Lipinszki, P. Kiss, M. Pál, P. Deák, Á. Szabó, E. Hunyadi-Gulyas, E. Klement, K.F. Medzihradszky and A. Udvardy
P018 A new role for the VCP/p97 AAA ATPase in proteasomal degradation
A. Beskow, K. Björk Grimberg and P. Young
P019 ZNF216-interacting proteins; implications for skeletal muscle atrophy
J. Strachan, J.R. Cavey, S.M. Gardiner, P.L. Greenhaff and R. Layfield
P020 Analysis of differences in retrotranslocation machineries of gp78- and Hrd1-mediated ERAD pathways by RNA interference.
P. Ballar and S. Fang
P021 Covalent attachment of SUMO proteins to Vaccinia virus E3L protein
J. Gonzalez-Santamaría, M. Campagna, L. Marcos-Villar, M. Angel García, F. Lopitz-Otsoa, M. Rodríguez, M. Esteban and C. Rivas
P022 Ribosomal protein gene transcription is regulated by the proteasome activator Blm10
A. Díaz López and M. Schmidt
P023 Interaction between viral AL1 and the plant SUMO-conjugating enzyme SCE1 is essential for plant infection and viral replication
M.A. Sanchez-Durán, M.B. Dallas, J.T. Ascencio-Ibañez, C.M. Guevara, J. Ruiz-Albert, L. Hanley-Bowdoin and E.R. Bejarano
P024 SUMOylation is a new post translational modifcation of Aurora-A that affects its malignant properties
I. Pérez de Castro, B. Martin, C. Aguirre, G. Fernández-Miranda, A. Klotzbucher, M. Kubbutat, M. Malumbres and Y. Arlot-Bonnemains
P025 Hybrid SUMO-2-ubiquitin chains drive the NF-kB inhibitor IkBa to proteasome mediated degradation
V. Lang, I. Egaña, F. Aillet, F. Lopitz-Otsoa, P. Pastor and M.S. Rodriguez
P026 Regulation of mitotic spindle positioning by SUMO and ubiquitin in yeast
D. Kammerer and D. Liakopoulos
P027 The SCF-FBXL14 ubiquitin ligase targets Snail1 for proteasome degradation
R. Viñas, M. Beltran, G. Valls, B. Montserrat-Sentís, J. Baulida, A. García de Herreros and V.M. Díaz
P028 Characterisation of human skeletal muscle MAFbx splice variants
J.R. Cavey, P.W. Sheppard, E. Day, A. Nedungadi, B. Shaw, M.P. Mee, P.L. Greenhaff and R. Layfield
|
|
Thursday 28 May
Poster Session 2, P029–P056 18:35–21:00
P029 Control of mammalian development and cell proliferation by the anaphase promoting complex (APC/C) ubiquitin ligase
E. Manchado, M. Eguren and M. Malumbres
P030 for Cks in APC/C-Cdc20-dependent destruction of cyclin A and cyclin B1
W. van Zon, J. Ogink, B. ter Riet and R. Wolthuis
P031 Protection by protein binding - a novel mechanism for synchronized degradation
J.K. Simpson and M. Brandeis
P032 Degradation of cyclin A is regulated by acetylation
F. Mateo, M. Vidal-Laliena, N. Canela, L. Busino, M.A. Martinez-Balbas, M. Pagano, N. Agell and O. Bachs
P033 Regulation of Aurora kinase B by the lipid raft protein Flotillin-1
V. Gómez, M. Sesé, A. Santamaría, J. Domingo Martínez, M. Soler, T.M. Thomson and R. Paciucci
P034 MPF and MAPK are required for inhibiting premature destruction of securin by APC/Cdh1 in mouse oocytes
I. Nabti, P. Marangos and J. Carroll
P035 Identifying DNA damage-associated de-ubiquitinating enzymes
L. Butler, E. Solomon and J. Morris
P036 Deubiquitinating enzymes and the DNA damage response
B. Le Tallec and S. Jentsch
P037 BRCA1 activity is regulated by the SUMO modification pathway in response to genotoxic stress
J.R. Morris, C. Boutell, M. Keppler, R. Densham, A. Alamshah, L. Butler, D. Weekes, Y. Galanty, L. Pangon, T. Ng and E. Solomon
P038 Cross-talks between ubiquitylation and acetylation in the regulation of p53
L.K. Linares, L. Le Cam, R. Kiernan, C. Chable-Bessia, C. Sardet, M. Benkirane and O. Coux
P039 Control of PCNA deubiquitylation in yeast
A. Gallego-Sánchez, F.M. Conde, I. Acosta, P.A. San Segundo and A. Bueno
P040 REV7-mediated polyubiquitination and degradation of human REV1
C.-S. Chun and D.-Y. Jin
P041 Phosphorylation-dependent degradation of JunB in G2 is mediated by the F-box protein Fbw7
S. Gallach, V. Baldin, M. Piechaczyk and R. Farràs
P042 In vivo biotinylation of neuronal ubiquitin substrates
U. Mayor
P043 Modulation of Aurora-A stability through its interaction with TPX2
M. De Luca, M. Giubettini, S. Floyd, G. Guarguaglini and C. Lindon
P044 Characterisation of the bacterial deubiquitinating enzyme elaD
D. Channing, E. Bolt, I. Kerr and R. Layfield
P045 Regulation of the S. pombe septation initiation network by the E3 ubiquitin ligase, Dma1
A.E. Johnson and K.L. Gould
P046 Interaction with Skp2 induces the proteasomal degradation of the small GTPase RhoE
M. Lonjedo, E. Mocholi, E. Poch, R.M. Guasch and I. Perez-Roger
P047 Impact of the proteasomal immune adaptation on the early immune response to HCMV infection
A. Warnatsch, M. Keller, F. Ebstein, C. Keller, J. Wagner, C. Hagemeier, A. Halenius, H. Hengel, P.-M. Kloetzel, U. Seifert and E. Krüger
P048 The Gid-E3 and Cdc48 machines are central components in ubiquitin-proteasome triggered regulation of carbohydrate metabolism in yeast
L. Barbin, O. Santt, T. Pfirrmann, B. Braun, J. Juretschke, F. Eisele and D.H. Wolf
P049 Identification of ASB2 substrates by label-free proteomics
C.F. Burande, M.L. Heuzé, I. Lamsoul, B. Monsarrat, S. Uttenweiler-Joseph and P.G. Lutz
P050 PI3K/Akt inhibits proteasomal degradation of AIB1
M. Ferrero, Á. Avivar and J. Font de Mora
P051 Proteasome regulation by AMP-activated protein kinase
D. Moreno, R. Viana and P. Sanz
P052 The role of ubiquitination in DNA damage response: proteomic analysis to identify new DNA-damage induced ubiquitinated proteins
J. Selvarajah and A. Moumen
P053 Functional and structural insights into the ASB2 E3 ubiquitin ligase
I. Lamsoul, N.F. Bello, C.F. Burande, D. Menoret, C. Moog-Lutz and P.G. Lutz
P054 Characterizing the role of AIRAPL as a new P97 adaptor
T. Galinka, I. Braunstein, M. Edelmann, B. Kessler and A. Stanhill
P055 Laforin, related to lafora progressive myoclonus epilepsy, protects from endoplasmic reticulum stress and proteasomal impairment
S. Vernia, T. Rubio, M. Heredia, S. Rodríguez de Córdoba and P. Sanz
P056 Proteasome involvement in amyotrophic lateral sclerosis
E. Onesto, M. Galbiati, D. Sau, V. Crippa, P. Rusmini, E. Bolzoni, A. Zito and A. Poletti
|
|
Friday 29 May
Poster Session 3, P057–P083 15:00–17:25
P057 A genome-wide siRNA screen for modulators of bortezomib-induced cell death
S. Chen, J.L. Blank, T. Peters, J. Liu, D. Rappoli, M.D. Pickard, S. Menon, J. Yu, D.L. Driscoll, T. Lingaraj, A.L. Burkhardt, J. Gray, D.S. Sappal, K. Garcia, P. Hales, P.J. Leroy, J. Ringeling, C. Rabino, J.J. Spelman, J.P. Morgenstern and E.S. Lightcap
P058 Development of a high-throughput assay to profile proteasome inhibition and activation in live cells
C.R. Berkers, K. Schuurman, B. Rodenko and H. Ovaa
P059 Observations and insights into the mechanisms of Ub and Ubl activating enzymes
J. Gavin, J. Brownell, F. Bruzzese, L. Dick, T. Soucy and K. Hamman
P060 Protein-protein interaction antagonists as novel inhibitors of non-canonical polyubiquitylation
J. Scheper, M. Guerra-Rebollo, G. Sanclimens, A. Moure, I. Masip, D. González-Ruiz, N. Rubio, B. Crosas, Ó. Meca-Cortés, N. Loukili, V. Plans, A. Morreale, J. Blanco, A.R. Ortiz, À. Messeguer and T.M. Thomson
P061 A comprehensive approach for detecting inhibitors of the therapeutic target USP7
S.J. Goldenberg, J.L. McDermott, K.G. Suresh Kumar, C.A. Leach, M.P. Kodrasov, D. Chauhan, Z. Tian, K.C. Anderson, M.R. Mattern and B. Nicholson
P062 Recent progress towards the identification of selective inhibitors of ubiquitin specific proteases
R. Lopez, V. Collura, C. Reverdy, C. Planquette, S. Conrath, P. Guedat, R. Delansorne, L. Daviet and F. Colland
P063 Live imaging and quantification of proteasome activity in C. elegans
O. Matilainen, G. Hamer and C.I. Holmberg
P064 A late domain-based pathway plays a key role during virus entry
H. Wodrich
P065 Parkin-mediated K63-linked polyubiquitination targets misfolded proteins to the aggresome-autophagy pathway
L.-S. Chin, J.A. Olzmann and L. Li
P066 The novel Alzheimer’s disease-associated protein ubiquilin-1 regulates presenilin-1 aggregation and formation of aggresomes
A. Haapasalo, J. Viswanathan, C. Böttcher, R. Miettinen, C.J. Maynard, A. Lu, H. Soininen, R.E. Tanzi, N.P. Dantuma and M. Hiltunen
P067 COP9 signalosome controls signal functions in the NF-kB system
K. Schweitzer and M. Naumann
P068 ER stress in Alzheimer’s disease: effects on the proteasome
D.A.T. Nijholt, T.R. de Graaf, L. Schmidt, E.S. van Haastert, R. Zwart, H. Ovaa, F. Baas, J.J. Hoozemans and W. Scheper
P069 Cbl and ubiquitination promote translocation of EGF receptor into clathrin-coated pits
V. Bertelsen, M.M. Sak, K. Breen, E. Stang and I.H. Madshus
P070 Proliferative role of LKB1 in the development of hepatocellular carcinoma associated to nonalcoholic-steatohepatitis
N. Embade Urrutia
P071 Regulation of gene expression in response to osmostress by the SAPK Hog1
C. Solé, G. Mas, À. Vendrell, N. Noriega, S. Regot, C. Ruiz, E. de Nadal and F. Posas
P072 Essential role of Lys63-linked ubiquitin chains in sorting to the multivesicular bodies in yeast
Z. Erpapazoglou, N. Belgareh-Touze, D. Urban-Grimal, S. Leon and R. Haguenauer-Tsapis
P073 Epsin 1 is involved in recruitment of ubiquitinated EGF receptors into clathrin-coated pits
M. Kazazic, V. Bertelsen, K.W. Pedersen, T.T. Vuong, M. Vibo Grandal, M.S. Rødland, L.M. Traub, E. Stang and I.H. Madshus
P074 A missense mutation of the mouse E3 ubiquitin ligase Herc1 results in Purkinje cells degeneration with severe ataxia
T. Mashimo, O. Hadjebi, T. Tsurumi, F. Amair-Pinedo, F. Langa Vives, T. Serikawa, C. Sotelo, J.-L. Guénet and J.L. Rosa
P075 he ubiquitin ligase Ariadne 1a regulates ecdysone response in D. melanogaster
A. Mansilla, A.-C. Gradilla and A. Ferrús
P076 Gap junction internalization by Eps15 requires Nedd4-mediated ubiquitination of Cx43
H. Girão, S. Catarino and P. Pereira
P077 A deubiquitylating enzyme Otubain1 affects cell susceptibility to infection with Yersinia by stabilizing the small GTPase RhoA
M.J. Edelmann, H. Kramer and B.M. Kessler
P078 Ubiquitination and MARCH I prevent MHC class II plasma membrane stabilization in non-activated dendritic cells
A. De Gassart, V. Camosseto, P. Pierre and E. Gatti
P079 Activation of autophagy after optic nerve transection in mice
N. Rodríguez-Muela, F. Germain and P. Boya
P080 Discovery of novel proteasome inhibitors, using a high-content cell-based screening system
I. Lavelin, Z. Kam, A. Navon, M. Oren, V. Rotter and B. Geiger
P081 Ubiquitin gene silencing provides protective effect at anoxia-reoxygenation modeling and decreases mRNA expression of GRP78, FRAP, PSMB5 and PSMB9 in cardiomyocytes
V. Kyrychenko, V. Nagibin, V. Dosenko, L. Tumanovska and O. Moibenko
P082 A genome wide RNAi screen to identify essential transcription factors for the proteasome pathway in Drosophila melanogaster
A. Beskow, K. Björk Grimberg and P. Young
P083 KCTD5, a putative substrate receptor for cullin3 ubiquitin ligases
A.G. Trinidad, Y. Bayon, M.L. de la Puerta, M. Sanchez Crespo and A. Alonso
|