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Localization and activation of Ras-like GTPases

21—23 March 2005

Royal Agricultural College, Cirencester, UK



22 March 2005

Poster Session 1: 13:30 - 16:00


P001 Activation of endogenous Ras is predominant at the plasma membrane
M. Augsten, R. Pusch, R. Wetzker, K. Friedrich and I. Rubio
P002 NMDA receptor-dependent translocation and activation of Rac is associated with memory formation in the mouse hippocampus
M.V. Tejada-Simon and E. Klann
P003 Rap1GAP2 is a new GTPase activating protein of Rap1 expressed in platelets
J. Schultess, O. Danielewski and A. Smolenski
P004 Engagement of syndecan-4 is essential for adhesion-stimulated Rac1 activation and focal complex formation
M.D. Bass, M.R. Morgan, Z. Mostafavi-Pour and M.J. Humphries
P005 K-Ras-mediated signal transduction in human pancreatic carcinoma cells
M. Unger, M. Müller, U. Dreißigacker, D. Pek, P. Gierschik and Klaudia Giehl
P006 Uncoupling of inhibitory and shuttling functions of rhoGDIs
E. Dransart, A. Morin, J. Cherfils and B. Olofsson
P007 ARL1 and ARF6 have essential roles in Trypanosoma brucei
H.P. Price, D. Goulding and D.F. Smith
P008 Engagement of syndecan-4 modulates the regulation of RhoA during cell spreading and stimulates p190RhoGAP by recruitment to the membrane
K. Roach, M. Bass and M. Humphries
P009 C-peptide activates Rac and Cdc42 and their downstream effectors PAK, LIMK and cofilin in CD4-positive cells
M. Aleksic, D. Walcher, K. Giehl and N. Marx
P010 Vip/pacap38 and NMDA facilitate dendrite formation by modifying the activities of the small Rho GTPases and phosphoinositide 3-kinase
J. Leemhuis, F. Henle, C. Fischer and D.K. Meyer
P011 Ras knockdown reveals isoform-specific signalling coupled to receptor activation
D.E. Hammond, M.J. Clague and I.A. Prior
P012 Co-ordination of vesicle tethering and cargo arrival at the Golgi?
A.K. Gillingham and S. Munro
P013 Design of a FRET-based biosensor to visualize the spatio-temporal activation of Pak1 kinase in living cells
M.C. Parrini, M. Matsuda and J. de Gunzburg
P014 How ArfGEFs couple stimulation of GDP/GTP exchange to membrane recruitment of Arf proteins
Louis Renault, Bernard Guibert and Jacqueline Cherfils
P015 Involvement of Rho in the activation of p38a in cerebellar granular neurons
J. Cao, M.M. Semenova and M.J. Courtney
P016 Involvement of small GTP-binding proteins in peroxisome biogenesis
E.A. Anthonio, P.P. Van Veldhoven and Marc Fransen
P017 A novel interaction between integrins and a Ras-like GTPase
T. Pellinen and J. Ivaska
P019 Identification of two putative RhoGAP proteins encoded by DEPDC1 and DEPDC1B genes
G. Volpi, P. Malatesta, G. Scita and R. Perris
P020 Recruitment of effectors to Golgi membranes by the Arl3p/Arl1p pathway
R. Behnia and S. Munro
P021 Targeting of the small GTPase ARL10c to the lysosomal membrane
I. Hofmann and S. Munro
P022 SAND-1 is an effector of RAB-7 and is required for endocytosis in Caenorhabditis elegans
D. Poteryaev, B. Bowerman and A. Spang
P023 Inhibition of post-translational prenylation causes sustained activation of Rac, Cdc42 and Rho GTPases
F.P. Coxon, J.E. Dunford and M.J. Rogers
P024 Modifications to the chemical structure of bisphosphonates affects their potency and specificity for preventing prenylation of small GTPases
J. Rojas Navea, M.J. Rogers, F.H. Ebetino, C.E McKenna, E.H. Mules, M.C. Seabra and F.P. Coxon
P025 A novel mode of GEF–GTPase interaction drives Rac1 targeting and activation by b-Pix
J.P. ten Klooster and P.L. Hordijk
P026 Functional differences between the isoforms of Rho with respect to epithelial–mesenchymal transition and proliferation of proximal tubule epithelial cells.
N. Hutchison, B.M. Hendry and C.C. Sharpe
P027 Trafficking of a novel GPI-anchored lipid-raft-associated protein
C. Hamilton, R. Rollason, V. Korolchuk and G. Banting
P028 A de-/reacylation cycle regulates the compartmentalised localisation and activity of palmitoylated Ras isoforms
O. Rocks, A. Peyker, M. Kahms, P.J. Verveer, C. Koerner, M. Lumbierres, J. Kuhlmann, H. Waldmann, A. Wittinghofer and P.I.H. Bastiaens
P029 Subcellular Targeting of Rab GTPases
C. Wasmeier, B.R. Ali and M.C. Seabra
P030 Localization-dependent activation of Ras isoforms
A. Peyker, O. Rocks and P. Bastiaens
P031 Role of RhoC in motility and cervical carcinoma
S. Srivastava, R. Bharathi and S. Krishna
P032 Spatio-temporal regulation of Rho GTPase function during macrophage phagocytosis
Céline Cougoule, Agnès Wiedemann, Jenson Lim and Emmanuelle Caron
P033 A possible role for Hsp90 in the prenylation of Rab GTPases
B.R. Ali, V.S. Lopes, L. Desnoyers, W.J. Henzel and M.C. Seabra
P034 Identification of a Ras effector associated exclusively with the early endosome
J. Carlton, J. Oakley and P.J. Cullen
P035 Employing live-cell imaging to visualise the control of Ras signalling by the Ras GTPase-activating proteins GAP1m and GAP1IP4BP
D. Bouyoucef, S. Kupzig and P.J. Cullen
P036 Spatial and temporal control of Ras signalling through receptor-mediated increases in intracellular free calcium
S. Kupzig, S.A. Walker, P.J. Lockyer and P.J. Cullen
P037 How novel Ca2+ sensors regulate Ras signalling in live cells
Q. Liu, R.S. Arkell, S.A. Walker, Y.-F. Dai, J.A. Taylor, D. Gao and P.J. Lockyer