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Neurotrophins: mechanisms in disease and therapy

6 April 2006

School of Chemistry, Bristol, UK



6 April 2006

Poster Session 1: 12:40 - 14:00


P001 Local treatment with a pan-neurotrophin binding decoy as a novel approach for asthma therapy
C. Nassenstein, D. Dawbarn, S.J. Allen, K. Pollock, E. Spies, N. Krug and A. Braun
P002 Neuro-immune interaction in allergic asthma: the role of the low-affinity pan-neurotrophin receptor p75NTR
C. Nassenstein, T. Kammertöns, E. Spies, N. Krug and A. Braun
P003 Characterization of symmetric complexes of nerve growth factor and the ectodomain of the pan-neurotrophin receptor, p75NTR
J.P. Aurikko, B.T. Ruotolo, J.G. Grossmann, M.C. Moncrieffe, E. Stephens, V.-M. Leppänen, C.V. Robinson, M. Saarma, R.A. Bradshaw and T.L. Blundell
P004 Neurotrophins promote angiogenesis. Potential implications for curing limb ischaemic and myocardial infarction
C. Emanueli
P005 Nerve growth factor - an inflammatory mediator in white adipose tissue?
M.R. Peeraully and P. Trayhurn
P006 Production, purification and characterization of recombinant human proNGF and binding to the TrkA, p75NTR and Sortilin receptors
O. Clewes, M.S. Fahey, S.J. Tyler, G. Wilcock, S.J. Allen and D. Dawbarn
P007 Proteolytic processing of proneurotrophins and their effects on vascular smooth muscle cell behaviour
K. Gray and V. Ellis
P008 Development of TrkAd5 (REN1820) as a soluble NGF receptor therapeutic agent
J.J. Watson, M.S. Fahey, E. van den Worm, F. Engels, F.P. Nijkamp, P. Stroemer, S. McMahon, S.J. Allen and D. Dawbarn
P009 Structural and functional studies of a neutralizing anti-NGF antibody unravel NGF mode of interaction to its receptors
S. Covaceuszach, P.V. Konarev, D.I. Svergun, D. Lamba and A. Cattaneo
P010 Structural and functional properties of mouse proNGF
F. Paoletti, S. Covaceuszach, P.V. Konarev, E. Schwarz, D.I. Svergun, A. Cattaneo and D. Lamba
P011 Spinal ERK phosphorylation regulates bladder overactivity caused by spinal cord transection
C.D. Cruz, S. McMahon and F. Cruz