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Translation UK (Satellite Meeting to BioScience2005)

21—23 July 2005

Western Infirmary, Glasgow, UK



21 July 2005

Poster Session 1: 19.00 - 20.30


P001 Control of MYEOV protein synthesis by upstream open reading frames
R. Alves de Almeida, T. Heuser, R. Blaschke, C.R. Bartram and J.W.G. Janssen
P003 Codon pair bias in prokaryotic and eukaryotic genomes
R. Buchan and I. Stansfield
P005 Inhibition of reporter gene expression by co-transfection of the cytomegalovirus promoter/enhancer
W. Thomas, A. Elia and M.J. Clemens
P007 Proteasome-mediated generation of a dephosphorylated fragment of the protein synthesis inhibitor 4E-BP1 that binds to eIF4E in cells with activated p53
C. Constantinou and M.J. Clemens
P011 Mutation of the eukaryotic initiation factor binding sites in eIF4GI results in the inability of eIF4GI to facilitate translation initiation
T.M. Hinton, M.J. Coldwell, S.J. Morley and J. Pain
P013 Investigating the subcellular localization of translation initiation factor eIF4F in NIH3T3 fibroblasts
M. Willett and J. Pain
P015 An IRES entirely downstream of its initiation codon
C.H. Herbreteau, L. Weill, D. Decimo, D. Prevot, J.-L. Darlix, B. Sargueil and T. Ohlmann
P017 A bioinformatic approach to identify novel 11 frameshift recoding events in Saccharomyces cerevisiae
E. Forbes, B. Moore, I. Ivanov and J.F. Atkins
P019 Structural and functional characterization of ribosomal translation initiation complexes
M. Nardelli, Y.E. Gordiyenko and J.E.G. McCarthy
P021 Mechanism of gene expression in the Tca2 retrotransposon
S. Greenwood, E. Forbes, F. Brunton, A. Glover and I. Stansfield
P023 Translational state array analysis of Arabidopsis cell cultures: effect of growth stage and cellular polyamine levels
C. Hanfrey and A.J. Michael
P025 Characterizing subunit interactions within eIF2B in Saccharomyces cerevisiae
C. Holtby and G.D. Pavitt
P027 Enhanced protein synthesis activity during the late growth phase in an antibiotic-overproducing rpsL mutant of Streptomyces coelicolor A3(2)
T. Hosaka, J. Xu and K. Ochi
P029 Trans-acting factor requirement in IRES activation during apoptosis
Y.W. Kong, T.L. Willmott, R. Hu, K. Sprigg, S.A. Mitchell, A.E. Willis and M. Bushell
P031 Functional analysis of the insulin receptor IRES
S. Mitchell, K. Spriggs, S. Ridley, K. Siddle and A. Willis
P033 Translational repression of MDR1 via inhibition of the PI3K/Akt/mTOR signalling pathway
R.A. O’Dwyer, S. Raguz, C.F. Higgins and E. Yague
P035 Expression of the eukaryotic translation initiation factor 4E (eIF4E) and 4E-BP1 in oesophageal cancer
Z. Salehi and F. Mashayekhi
P037 Translational control of inducible nitric oxide synthase by arginine availability and arginase in vitro and in vivo
U. Schleicher, T. König and C. Bogdan
P039 Global gene expression profiling reveals widespread, yet distinctive, translational responses to different eIF2B-targeting stress pathways
J. Smirnova, J. Selley, K. Carroll, R. Pearson, F. Sanchez-Cabo, G.D. Pavitt, J.E.G. McCarthy, S. Hubbard, C. Grant and M.P. Ashe
P041 Eukaryotic initiation factors induce structural rearrangements in the small 40S subunit of the eukaryotic ribosome – a cryo-EM study
R.J.C. Gilbert, A.F.-P. Sonnen, G. Hofmann, Y. Gordiyenko, T. von der Haar, M. Nardelli, D.I. Stuart and J.E.G. McCarthy
P043 The role of poly(A)-binding proteins in translational control
G.S. Wilkie, R. Anderson and N.K. Gray
P045 The role of pacman protein in adult Drosophila male fertility
M.V. Zabolotskaya, C.L. Roberts and S.F. Newbury

22 July 2005

Poster Session 2: 18.00 - 19.30


P002 Crystal structure of foot-and-mouth disease virus 3C protease
J.R. Birtley, S.R. Knox, A.M. Jaulent, P. Brick, R.J. Leatherbarrow and S. Curry
P004 A proteomics approach to studying stress responses in Saccharomyces cerevisiae
K.M. Carroll, J. Smirnova, J. Selley, S.J. Hubbard, G.D. Pavitt, J.E.G. McCarthy, M.P. Ashe and C.M. Grant
P006 Regulation of protein synthesis initiation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53
C. Constantinou and M.J. Clemens
P008 Regulation of protein synthesis in human tumour cells by treatment with interferon-a and TRAIL
I.W. Jeffrey, S. Bornes, V. Tilleray and M.J. Clemens
P010 Identification of the trans-acting factors of the L- and N-myc IRES
L. Cobbold, K. Spriggs, S. Mitchell and A.E. Willis
P012 Re-programming of translation in C2C12 myoblasts during differentiation
J.L. Cowan and S.J. Morley
P014 The La autoantigen and its interaction with cognate RNAs
M.R. Conte, D. Sanfelice, C. Alfano, J. Babon, G. Kelly and S. Curry
P016 Further analysis of the BAG-1 IRES and specific trans-acting factors
H.C. Dobbyn, K.A. Spriggs, B.M. Pickering, J. Emsley and A.E. Willis
P018 Profiling non-Hodgkin’s lymphoma cell lines using translation cDNA microarray
P.J. Goodrem, M. Bushell and A.E. Willis
P020 The stem-loop binding protein stimulates histone translation at an early step in the initiation pathway
B. Gorgoni, S. Andrews, A. Schaller, D. Schümperli, N.K. Gray and B. Müller
P022 The importance of scanning distance in N-myc IRES function
S. Haines, K. Spriggs, S. Mitchell, L. Cobbold and A. Willis
P024 Glucose-mediated changes in intracellular ATP concentration regulate eIF2a phosphorylation but not protein synthesis in pancreatic b-cells
M.L. Powell and T.P. Herbert
P026 Translational microarray analysis of chronic lymphocytic leukaemia
L. Hornsby, H. Rogers, A. Willis, M. Dyer and T. Gant
P028 Experimental normoxia conditions for hepatic cells, post-transcriptional level of gene expression
M. Brocard, A. Lepelletier, M. Galby, S. Charreton, S. Paulous, K.M. Kean and A. Komarova
P030 Biophysical analysis of eukaryotic translation initiation factor-4A (eIF4A)
S.J. Marsden, M. Nardelli, T. von der Haar and J.E.G. McCarthy
P032 Visualization of a viral pseudoknot inducing frameshifting in a mammalian ribosome
S. Moran, O. Namy, D. Stuart, I. Brierley and R. Gilbert
P034 Residues important for the function of eIF2B?
S.S. Mohammad-Qureshi and G.D. Pavitt
P036 Flux control analysis of translation initiation and differential control of gene expression
P. Sangthong, K.M. Carroll, J.M.X. Hughes and J.E.G. McCarthy
P038 Analysis of eIF4E overexpression in skin cancers
F. Shahhosseini and Z. Salehi
P040 Elucidating the mechanism of Dazl-mediated translation
J.W.S. Smith and N.K. Gray
P042 The 59-39 exoribonuclease pacman and its role in wound healing
M.J. Sullivan, M.V. Zabolotskaya, H.L. Glenwright and S.F. Newbury
P044 Translational recruitment of pro-apoptotic genes via IRES elements during the induction of apoptosis
T. Willmott, I. Powley, A. Willis and M. Bushell
P046 Ubiquitination and degradation of the eIF4E-binding protein 4E-BP1 and its regulation by TRAIL
A. Elia, I.W. Jeffrey and M.J. Clemens