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Past Conferences > Matrix turnover > Poster Abstracts

Matrix turnover — mechanisms and common denominators: a Joint British Society for Matrix Biology/Biochemical Society Focused Meeting

2—3 April 2007

Sheffield Hallam University, UK



2 April 2007

Poster Session 1: 18:40-19:30


P001 Lipoprotein receptor-related protein 1 serves as binding partner to localize secreted cathepsin B to the surface of migrating HaCaT keratinocytes
S. Dannenmann, H. Büth, M. Rehders, R. Ostafe, C. Pietrzik, P. Boukamp and K. Brix
P003 UGDH is a positive modulator of GAG production and chondrogenesis
C.E. Clarkin, S. Allen, B.T. Wheeler, C.P.D. Wheeler-Jones and A.A. Pitsillides
P005 Investigation of the remodelling response of human tenocytes to anabolic and catabolic factors when cultured in 3D collagen gels
A.N. Corps, V.A. Curry, R.L. Harrall, B.L. Hazleman and G.P. Riley
P007 FGFR3, osteoarthritis and hypertrophic differentiation
E.A. Crawford, K.E. Silverthorne, R.J. Wardale, G.A. Wallis and R.P. Boot-Handford
P009 Expression and functional characterization of the G1 domain from human versican.
H.L. Fielder, N.T. Seyfried, M. Noble and A.J. Day
P011 Relationship between cerebral palsy induced spasticity and tendon collagen turnover
N. Gagliano, F. Pelillo, O. Picciolini, F. Grizzi, M. Gioia and N. Portinaro
P013 Ullrich congenital muscular dystrophy fibroblasts and their adhesion to extracellular matrix proteins
C. Jimenez-Mallebrera, J. Kim, S. Brown, L. Feng and F. Muntoni
P015 Pharmacological regulation of adult stem cells: chondrogenesis can be induced using a synthetic inhibitor of the retinoic acid receptor
W. Kafienah, S. Mistry, M.J. Perry, G. Politopoulou and A.P. Hollander
P017 Gene targeting collagen XXVII
D.A. Plumb, M.D. Briggs, D.J. Thornton, K.E. Kadler and R.P. Boot-Handford
P019 Furin regulates hypoxic inhibition of MMP-2 activation in human cardiac fibroblasts
K. Riches, M.E. Morley, C. Peers and K.E. Porter
P021 Teleost bone and cartilage ECM proteins
F.A. Vieira and D.M. Power
P023 A novel role for COX-2 regulating HA synthesis and binding in developing joints
B.T. Wheeler, C.E. Clarkin, C.P.D. Wheeler-Jones and A.A. Pitsillides
P025 The influence of nutrient supply on the growth of intervertebral disc cells
E. Johnson, S. Stephan and S. Roberts
P027 Age-related changes of cytoskeletal composition: a preliminary study of the role of cytoskeleton in intervertebral disc degeneration
S. Li, E.J. Blain and V.C. Duance
P029 Bovine brain matrix metalloproteinases; detection and inhibition
E. Ganea, M. Trifan, A.C. Laslo, G. Putina and C. Cristescu
P031 Fibrillin-1 regulates the bioavailability of TGFb1
S.S. Chaudhry, S.A. Cain, A. Morgan, S.L. Dallas, C.A. Shuttleworth and C.M. Kielty
P033 Tenascin-C regulates fibroblast migration within 3D fibrin–fibronectin matrices
A. Trebaul, E. Chan and K. Midwood
P035 Bone marrow stromal cell-derived insulinslike growth factor (IGF) II enhances growth and survival of prostate cancer cells and potentiates androgen action
N.A. Cross, M. Papageorgiou, J. Lippitt, R. Nyambo, F.C. Hamdy and C.L. Eaton
P037 Analysis of prostate tumour cell invasion using BD FluoroBlok™ insert systems and the FLUOstar OPTIMA fluorescence microplate reader
C.A. Hart, N.W. Clarke and M.D. Brown
P039 Imaging proteolysis in prostate cancer and stromal cells
C.N. Molokwu, O.O. Adeniji, F.C. Hamdy and D.J. Buttle
P041 Exploring new roles for cathepsin K in prostate cancer
I. Podgorski, B.E. Linebaugh and B.F. Sloane
P043 Phagocytosis of collagen by fibroblasts and invading cancer cells is mediated by MT1-MMP
H.R. Lee, K.L. Sodek, Q. Hwang, T.J. Brown, M. Ringuette and J. Sodek

3 April 2007

Poster Session 2: 13:40-14:40


P002 The serine protease HtrA1 regulates physiological and pathological matrix mineralization
A.E. Canfield, K.D. Hadfield, C.F. Rock, E.C. Wylie and F.L. Wilkinson
P004 IL1-mediated loss of aggrecan from articular cartilage is MMP17 dependent
K. Clements, J. Flannelly, J. Tart, S. Brockbank, J. Wardale, J. Freeth, A. Parker and P. Newham
P006 Identifiying the molecular basis of arthritis
T. Coughlan, A. Crawford, P. Hatton and M. Barker
P008 The molecular basis of inter-a-inhibitor heavy chain transfer on to hyaluronan
W. Tongsoongnoen, M.S. Rugg, A.C. Willis, E. Fries, C.M. Milner and A.J. Day
P010 Collagen turnover analysis in human gingival fibroblasts treated with different doses of FK506
N. Gagliano, C. Moscheni, S. Selleri, C. Torri, G. Tartaglia, F. Costa and M. Gioia
P012 Hyaluronan turnover in synovial joints
K.R. Ingram, A. Wann and J.R. Levick
P014 Evidence for increased elastin turnover in achilles tendon pathology
G.C. Jones, N. Avery, A.N. Corps, B.L. Hazleman and G.P. Riley
P016 Influence of the extracellular matrix on the mechanical properties of tissue engineered cartilage
M. Plainfosse, P.V. Hatton, A. Crawford, J. Katta, Z. Jin and J. Fisher
P018 MMP-9 activity in myoblasts and fibroblasts is interactively influenced by mechanical load and substrate
P.P. Purslow and M.C. Cha
P020 Fabricating a heparin gradient
D.E. Robinson, A. Marson, A.J. Day, D.J. Buttle and R.D. Short
P022 Graded coupling of hyaluronan secretion to joint movement; role of transcription/translation.
A.K.T. Wann, K. Ingram and J.R. Levick
P024 Mechanical environment of cartilage cells
M. Adams
P026 Immunolocalisation of matrix proteins in the intervertebral disc and endplate in scoliosis
P.N. Jones, J. Menage, S.M. Eisenstein, W.E.B. Johnson and S. Roberts
P028 Astrocyte–leucocyte interactions and the mechanisms regulating matrix degradation in CNS tuberculosis
J.E. Harris, R.K. Nuttall, J.A. Green, P.T. Elkington, M.B. Graeber, D.R. Edwards and J.S. Friedland
P030 Changes in brain expression of chondroitin sulphate proteoglcans (CSPGs) following transient middle cerebral artery occlusion in the rat
G. Haddock, A.K. Cross, S. Allan, R.A.D. Bunning, D.J. Buttle and M.N. Woodroofe
P032 Biochemical evaluation of hepatocellular dysfunction and extracellular matrix alteration in mice infected with Schistosoma mansoni
F. A. Kassim and B.A. Iwalokun
P034 TIMP-3 expression in prostate stromal and tumour cells is regulated by androgen and TNF
O.O. Adeniji, C.N. Molokwu, E.A. Waterman, N.A. Cross, F.C. Hamdy and D.J. Buttle
P038 Distinct roles of the haemopexin and the transmembrane domains as dimer interfaces of MT1-MMP on the cell surface
Y. Itoh, N. Ito, Y. Otake, H. Nagase and M. Seiki
P040 Regulation of ADAMTS expression in prostate cancer and stromal cells by androgen and TNF
C.N. Molokwu, O.O. Adeniji, F.C. Hamdy and D.J. Buttle
P042 Breast cancer cell migration through Matrigel™: the importance of glycosidase enzymes
K. Ramessur, P. Greenwell, M.V. Dwek
P044 Tumour cell–bone marrow stromal cell interactions modify expression of cathepsin K, ADAMTS-15, TIMP-3 and osteoprotegerin (OPG)
J. Woodward, D. Lefley, N. Cross, P.D. Ottewell, D.J. Buttle, R.E. Coleman and I. Holen