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New approaches for elucidating protease biology and therapeutic opportunities

4—6 January 2007

Royal Agricultural College, Cirencester, UK



5 January 2007

Poster Session 1: 16:15 - 18:00


P001 Protease response domain in immuno-reproductive failure.
A.O. Dare, S. Adeola and S. Ronke
P002 An alternative strategy for inhibiting multidrug-resistant mutants of the dimeric HIV-1 protease by targeting the subunit interface
L. Bannwarth, T. Rose, A. Vidu, R. Vanderesse, S. Sicsic, S. Ongeri and M. Reboud-Ravaux
P003 Linear mimics of the natural proteasome inhibitor TMC-95A: design, synthesis and biological evaluation
N. Basse, P. Sarthou, A. Ferrier-Berthelot, M. Pagano, S. Piguel, J. Vidal, J. Sobczak and M. Reboud-Ravaux
P004 NMR studies of the inhibition of pepsin by peptide glyoxal inhibitors
S. Cosgrove, L. Rogers, C. Hewage and J.P.G. Malthouse
P005 Degradation of fibrinogen by CF-related pathogens
G.G. Einarsson, S.L. Martin, B. Walker, J.S. Elborn and A. McDowell
P006 Unravelling the moulting degradome of nematodes: new opportunities for chemotherapy
H. Craig, R.E. Isaac and D.R. Brooks
P007 Inhibition of ADAMTS-4/-5 by N-terminal N-TIMP-3 mutants
N.H. Lim, M. Kashiwagi, S. Wei, K. Brew and H. Nagase
P008 TTR proteolytic activity enhances apoA-I fibril formation
M. Almeida Liz, M.J. Saraiva and M. Mendes Sousa
P009 Protein domains regulating the potency of therapeutic thrombolytic proteases
S. Williams, C. Longstaff, K. Brown and C. Thelwell
P010 Eppin: a new proteinaceous protease inhibitor?
M.T.C. McCrudden, P. Turkington, J. Mann and D.J. Timson
P011 The role of cathepsin S in astrocytoma invasion
C. McGoohan, W. Chen, T. Chen, C. Shaw and B. Walker
P012 Investigation of a novel serine protease involved in cell survival
K.L. Moffitt, S.L. Martin and B. Walker
P013 Rab5c is a component of the BACE complex
R.B. Parsons, C.G. Olsen, D. Subramaniam and B.M. Austen
P014 Analysis of b-secretase kinetics and the protein levels of BACE1 and BACE2 in human control and Alzheimer’s disease brain.
J.H. Stockley, R. Ravid and C. O’Neill