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Structural glycobiology and human health

30—31 March 2010

Royal Holloway, University of London, UK



Organizers:
Barbara Mulloy (NIBSC, UK)
Tony Corfield (University of Bristol, UK)

Session 1: Structural Glycobiology and Human Health

 

Tuesday 30 March 2010
12:00 - 13:30 Registration and Lunch

13:30 Welcome

13:40 - 14:10
GlycoBiomimics and GlycoBiosensors
Lokesh Joshi (National University of Ireland, RoI)
14:10 - 14:40
Structural insights into chondroitin sulphate binding during pregnancy-associated malaria
Matthew Higgins (University of Cambridge, UK)
14:40 - 15:10
Glycosaminoglycan-protein interactions in inflammatory processes
Tony Day (University of Manchester, UK)
15:10 - 15:40
Henipavirus attachment: a structural basis for viral specificity
Thomas Bowden (University of Oxford, UK)
15:40 - 16:10 Coffee/tea break

16:10 - 16:25
Human UDP-glucose dehydrogenase: The potential of structural and molecular enzymology as tools for cancer therapy
Selected oral communication - Sigrid Egger (Graz University of Technology, Austria)
16:25 - 16:40
Phage P22 tailspike function during infection cycle
Selected oral communication - Dorothee Andres (University of Potsdam, Germany)
16:40 - 17:40
Structural enzymology of the O-GlcNAc modification: probing the proposed links to type II diabetes and neurodegeneration
Gideon Davies - GlaxoSmithKline Award Lecture (University of York, UK)
17:40 - 19:10 Drinks reception and poster session

19:30 Conference dinner

Session 2: Glycosystematics

 

Wednesday 31 March 2010
09:00 - 09:30
Systems biology of heparan sulphate: a glycomics challenge
Jeremy Turnbull (University of Liverpool, UK)
09:30 - 10:00
Carbohydrate microarrays in studies of the molecular basis of pathogen-host interactions
Yan Liu (Imperial College London, UK)
10:00 - 10:15
A chemical genetic approach to the study of the TLR4 pathway: new sugar-derived compounds targeting selectively the CD14 and MD-2 receptors
Selected oral communication - Francesco Peri (University of Milano Bicocca, Italy)
10:15 - 10:30
Decreased levels of bisecting GlcNAc glycoforms of IgG mark human longevity
Selected oral communication - Renee Ruhaak (Leiden University Medical Center, The Netherlands)
10:30 - 11:00 Coffee/tea break

11:00 - 11:30
Ionic liquids in oligosaccharide synthesis: toward mucin type glycan probes
Carmen Galan (University of Bristol, UK)
11:30 - 12:00
Glycomics and human health: a tight relation
Aristotelis Antonopoulos (Imperial College London, UK)
12:00 - 13:00 Lunch

13:00 - 13:30
Systems glycobiology: A robotic HPLC based platform with computer assisted data interpretation for biomarker discovery, monitoring therapeutics and establishing the variability, heritability and environmental determinants of human plasma N-glycome
Pauline Rudd (University College Dublin, RoI)
13:30 - 15:00
Round Table Discussion
15:00 Closing remarks