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Genome instability and cancer

4 December 2008

National University of Ireland Galway, Ireland



Organizer:
Michael Carty (National University of Ireland Galway, Ireland)
Thursday 4 December 2008
09:00 - 09:30 Registration and coffee/tea

09:30 - 09:50
Investigation of the role of histone methylation in the cellular response to DNA damage
Selected oral communication - Jennifer Fitzgerald (National University of Ireland, Galway)
09:50 - 10:10
A novel mass spectrometric method for studying DNA damage
Selected oral communication- Tony Merrigan (Queens University Belfast, Ireland)
10:10 - 10:50
SUMO modification of PCNA is controlled by DNA
Joanne Parker (Cancer Research, UK)
10:50 - 11:10 Coffee/tea break

11:10 - 11:30
Cyclophilin A; a novel regulator of genome stability in haematopoietic cells
Selected oral communication - John Bannon (University College Dublin, Ireland)
11:30 - 11:50
Modelling the Comet assay
Selected oral communication- Darragh McArt (University of Ulster, UK)
11:50 - 12:30
DNA replication repair: basic mechanisms and anti-cancer therapy
Thomas Helleday (University of Oxford, UK)
12:30 - 13:30 Lunch and poster viewing

13:30 - 14:30
Irish Area Section Gold medal
Therese Kinsella (University College Dublin, Ireland)
14:30 - 14:50
Genome wide effects of microRNA-21 (mir-21) knock-down on transcriptome of breast cancer cells
Selected oral communication - Duygu Selcuklu (University College Cork, Ireland)
14:50 - 15:10
Nuclear structures involved in the modulation of the DNA damage response of human cells
Selected oral communication - Ronan Broderick (NUI, Galway)
15:10 - 15:50
Regulation of Rad1/XPF by Slx4 family members
John Rouse (University of Dundee, UK)
15:50 - 16:10 Coffee/tea break

16:10 - 16:30
Selected oral communication - to be announced
16:30 - 16:50
Selected oral communication - to be announced
16:50 - 17:30
Discovery a novel class of anticancer agents targeting DNA replication
Corrado Santocanale (National University of Ireland, Galway)
17:30 - 19:30 Drinks reception and poster session