Special Events
Host Departmental Lecture
Pathogen-derived immunomodulatory molecules - the bridge between innate and adaptive immunity
Kingston Mills (Maynooth, Ireland)
Timetable
|
DNA Damage Signalling and Apoptosis
Host colloquium
Organizers:
Danny Zisterer (Dublin, Ireland)
Marion Boland (Cambridge, UK)
Stephen Jackson (Cambridge, UK)
Sponsor:
BioResearch Ireland
Signalling and repair of DNA damage
Stephen Jackson (Cambridge, UK)
Molecular mechanisms of nucleotide excision repair
Jan Hoeijmakers (Rotterdam, The Netherlands)
Transducing the DNA damage signal in yeast
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
Host Departmental Lecture
Pathogen-derived immunomodulatory molecules - the bridge between innate and adaptive immunity
Kingston Mills (Maynooth, Ireland)
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
ATM: genome stability, neuronal development and cancer cross paths
Yossi Shiloh (Tel Aviv, Israel)
Choosing between growth arrest and apoptosis through RB, Abl and p73
Jean Wang (California, USA)
15:15 - 16:45 Poster Session, Trade Exhibition and Tea Break
DNA damage signalling and NF-kB: mechanisms of activation and implications for death
Marion Boland (Cambridge, UK)
Uncovering BRCA1 regulated signalling pathways by microarray based expression profiling
Denis Paul Harkin (Belfast, UK)
Doug Green (California, USA)
Transcriptional regulation by NF-kB and p300/CBP
Neil Perkins (Dundee, UK)
Secondary DNA structures as molecular targets for cancer therapeutics
Lawrence Hurley (Tucson, USA)
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
Adding function to structure in proteomics using SPR
Caspase activation and effector function during the demolition phase of apoptosis
Seamus Martin (Dublin, Ireland)
Cytotoxic signaling by inhibitors of DNA topoisomerase II
William T Beck (Chicago, USA)
15:15 - 16:45 Poster Session, Trade Exhibition and Tea Break
Pyrrolo-1,5-benzoxazepines: a new class of apoptotic agents
Daniela Zisterer (Dublin, Ireland)
The protective role of HSP on HL-60 cell apoptosis
Transient Jun N-terminal kinase (JNK) activation and suppression of
apoptosis by IGF-I
A human cell culture system for studying post-translational
regulation of p53 at physiological levels
Oncogenes, apoptosis and cancer, with special emphasis on p53 and c-Myc
Gerard Evan (San Francisco, USA)
|
Neurotransmitter Transporters: Molecular Mechanism and Regulation
Neuroscience Group colloquium
Organizers:
Clive Williams (Dublin, Ireland)
Jana Haase (Dublin, Ireland)
Sponsor:
BioResearch Ireland
Molecular characterization of substrate binding sites in glutamate transporter family
Baruch Kanner (Jerusalem, Israel)
Molecular cloning and characterization of hemicholinium-3 sensitive choline transporters
Subbu Apparsundaram (Kentucky, USA)
Molecular mechanisms of cystine and glutamate transport
Gethin McBean (Dublin, Ireland)
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
Host Departmental Lecture
Pathogen-derived immunomodulatory molecules - the bridge between innate and adaptive immunity
Kingston Mills (Maynooth, Ireland)
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
SERT biosynthesis and the problems of over-expression for structural studies
Chris Tate (Cambridge, UK)
Regulation of the serotonin transporter by interacting proteins
Jana Haase (Dublin, Ireland)
15:15 - 16:45 Poster Session, Trade Exhibition and Tea Break
On the structure, function and regulation of the serotonin transporter
Sandra Horschitz (Mannheim, Germany)
The impact of oligomerization on the function of the serotonin transporter
Harald H.Sitte (Vienna, Austria)
Up, Down, Fast, Slow, Here and There: Regulating GABA transporter function
Michael Quick (Birmingham, USA)
Regulation of glycine transporters
Beatriz Lopez Corcuera (Madrid, Spain)
Molecular determinants involved in the asymetrical distribution of glycine transporters in polarized cells
Francisco Zafra (Madrid, Spain)
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
Adding function to structure in proteomics using SPR
|
Mitochondrial Uncoupling Proteins
Bioenergetics Group colloquium
Organizers:
Martin D. Brand (Cambridge, UK)
Richard Porter (Dublin, Ireland)
Sponsors:
Novo Nordisk (Denmark)
Specificity in toll-like receptor function
Adrian Ozinsky (Washington, USA)
How the innate immune system senses infection
Bruce Beutler (California, USA)
The Toll receptors and the antimicrobial defenses of Drosophila
Jean-Marc Reichhart (Strasbourg, France)
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
Host Departmental Lecture
Pathogen-derived immunomodulatory molecules - the bridge between innate and adaptive immunity
Kingston Mills (Maynooth, Ireland)
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
Toll-like receptors in innate immune recognition
Ruslan Medzhitov (New Haven, USA)
Dimerization of the CD45 RPTPase inhibits its function in vivo and is necessary in order to prevent autoimmunity
Arthur Weiss (California, USA)
15:15 - 16:45 Poster Session, Trade Exhibition and Tea Break
Visualizing the spatial and temporal orchestration of T cell activation
Abraham Kupfer (California, USA)
Lipid rafts and T cell receptor signalling
The importance of ectodomain size in TCR triggering
Anton van der Merwe (Oxford, UK)
|
UCP 1 and its Homologues
Chair:
Richard Porter (Dublin)
David Nicholls (California, USA)
Lymphocyte signalling and the role of the LAT molecule
Lawrence E. Samelson (Maryland, USA)
The role of adapter proteins in T cell activation
Gary A. Koretzky (Pennsylvania, USA)
Jan Nedergaard (Stockholm, Sweden)
The function of UCP1 homologues
Martin Brand (Cambridge, UK)
Vav1 transduces TCR signals modulating lymphocyte adhesion and morphology
Victor Tybulewicz (London, UK)
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
Adding function to structure in proteomics using SPR
|
In Vivo UCP Expression Systems
Chair:
Jean-Paul Giacobino (Geneve)
Lymphocyte signalling and the role of the LAT molecule
Lawrence E. Samelson (Maryland, USA)
The role of adapter proteins in T cell activation
Gary A. Koretzky (Pennsylvania, USA)
Vav1 transduces TCR signals modulating lymphocyte adhesion and morphology
Victor Tybulewicz (London, UK)
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
Adding function to structure in proteomics using SPR
UCP3 expression and function: studies with transgenic mice and human muscle
Mary-Ellen Harper (Ontario, Canada)
Peter Parker (ICRF, London, UK)
Uncoupling protein 2: expression and function
Daniel Ricquier (Meudon, France)
Signal transduction downstrean of PI 3-kinase
Dario Alessi (Dundee, UK)
15:15 - 16:45 Poster Session, Trade Exhibition and Tea Break
Tec family kinases in T cell receptor signaling
Pam Schwartzberg (Bethesda, USA)
(Poster and Speakers To Be Announced)
Oral Poster Presentations
Signalling by the small GTPases Ras, Ral and Rap1
Hans Bos (Utrecht, The Netherlands)
|
UCP Function
Chair:
Barbara Cannon (Stockholm)
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
Adding function to structure in proteomics using SPR
Peter Parker (ICRF, London, UK)
Signal transduction downstrean of PI 3-kinase
Dario Alessi (Dundee, UK)
15:15 - 16:45 Poster Session, Trade Exhibition and Tea Break
Uncoupling protein 3 biological activity
Jean-Paul Giacobino (Geneva, Switzerland)
Tec family kinases in T cell receptor signaling
Pam Schwartzberg (Bethesda, USA)
(Poster and Speakers To Be Announced)
Oral Poster Presentations
Stefan Krauss - Selected Poster Abstract
Development of a hybrid protein to study the 3D structure of UCP1 matrix loops
Amalia Ledesma - Selected Poster Abstract
Clare Brennan - Selected Poster Abstract
Genetics of uncoupling proteins
Craig Warden (Davis, USA)
Signalling by the small GTPases Ras, Ral and Rap1
Hans Bos (Utrecht, The Netherlands)
|
UCP's and Metabolism
Chair:
Martin Brand (Cambridge, UK)
Brain UCPs: localization and functions
Denis Richard (Quebec, Canada)
SOCS proteins - negative regulators of the cytokine signal transduction
Warren Alexander (Victoria, Australia)
Role of Gab2 in allergic response
Benjamin Neel (Boston, USA)
UCP2 is a negative regulator of glucose-stimulated insulin secretion
Chen-yu Zhang (Boston, USA)
Uncoupling protein 3 and fatty acid metabolism
Abdul Dulloo (Fribourg, Switzerland)
The SAP/SLAM defence system
Cox Terhorst (Boston, USA)
11:00 - 11:30 Coffee Break,Trade exhibition and Poster Viewing
Mitochondrial uncoupling and lipid metabolism in adipocytes
Jan Kopecky (Prague, Czech Republic)
Dr Tonks has been elected as a Fellow of the Royal Society and is unable to attend the Dublin Meeting. The Biochemical Society conveys warm congratulations to Dr Tonks
Nicholas K. Tonks - cancelled (New York, USA)
12:15 - 14:00 Lunch Break, Trade Exhibition and Poster Session
|
UCP Mechanism
Chair:
Jan Nedergaard (Stockholm)
12:15 - 14:00 Lunch Break, Trade Exhibition and Poster Session
Perspectives on the biology of UCP homologues
Sean Adams (California, USA)
Mechanism of uncoupling protein action
Keith Garlid (Beaverton, USA)
Uncoupling protein function
Martin Klingenberg (Munich, Germany)
The control of transport in the uncoupling proteins UCP1 and UCP2
Eduardo Rial (Madrid, Spain)
|
Signal Transduction During Innate and Adaptive Immunity
Molecular and Cellular Pharmacology Group and Immunology Group colloquium
Organizers:
Melanie Welham (Bath, UK)
Doreen Cantrell (ICRF, London, UK)
Luke O'Neill (Dublin, Ireland)
Sponsors:
GlaxoSmithKline
Mechanism of uncoupling protein action
Keith Garlid (Beaverton, USA)
Uncoupling protein function
Martin Klingenberg (Munich, Germany)
The control of transport in the uncoupling proteins UCP1 and UCP2
Eduardo Rial (Madrid, Spain)
|
Toll Like Receptors
Chair:
Professor Luke O'Neill (Dublin)
Specificity in toll-like receptor function
Adrian Ozinsky (Washington, USA)
How the innate immune system senses infection
Bruce Beutler (California, USA)
The Toll receptors and the antimicrobial defenses of Drosophila
Jean-Marc Reichhart (Strasbourg, France)
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
Host Departmental Lecture
Pathogen-derived immunomodulatory molecules - the bridge between innate and adaptive immunity
Kingston Mills (Maynooth, Ireland)
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
|
Lymphocyte Signalling
Chair:
Dr Steve Ward (Bath)
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
Dimerization of the CD45 RPTPase inhibits its function in vivo and is necessary in order to prevent autoimmunity
Arthur Weiss (California, USA)
15:15 - 16:45 Poster Session, Trade Exhibition and Tea Break
Visualizing the spatial and temporal orchestration of T cell activation
Abraham Kupfer (California, USA)
Lipid rafts and T cell receptor signalling
The importance of ectodomain size in TCR triggering
Anton van der Merwe (Oxford, UK)
|
Signal Integration in Lymphocytes
Chair:
Dr Doreen Cantrell (London)
David Nicholls (California, USA)
Lymphocyte signalling and the role of the LAT molecule
Lawrence E. Samelson (Maryland, USA)
The role of adapter proteins in T cell activation
Gary A. Koretzky (Pennsylvania, USA)
Jan Nedergaard (Stockholm, Sweden)
The function of UCP1 homologues
Martin Brand (Cambridge, UK)
Vav1 transduces TCR signals modulating lymphocyte adhesion and morphology
Victor Tybulewicz (London, UK)
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
Adding function to structure in proteomics using SPR
UCP3 expression and function: studies with transgenic mice and human muscle
Mary-Ellen Harper (Ontario, Canada)
Peter Parker (ICRF, London, UK)
Uncoupling protein 2: expression and function
Daniel Ricquier (Meudon, France)
Signal transduction downstrean of PI 3-kinase
Dario Alessi (Dundee, UK)
15:15 - 16:45 Poster Session, Trade Exhibition and Tea Break
Uncoupling protein 3 biological activity
Jean-Paul Giacobino (Geneva, Switzerland)
Tec family kinases in T cell receptor signaling
Pam Schwartzberg (Bethesda, USA)
(Poster and Speakers To Be Announced)
Oral Poster Presentations
Stefan Krauss - Selected Poster Abstract
Development of a hybrid protein to study the 3D structure of UCP1 matrix loops
Amalia Ledesma - Selected Poster Abstract
Clare Brennan - Selected Poster Abstract
Genetics of uncoupling proteins
Craig Warden (Davis, USA)
Signalling by the small GTPases Ras, Ral and Rap1
Hans Bos (Utrecht, The Netherlands)
|
Signalling Homeostasis I
Chair:
Dr Melanie Welham (Bath)
Brain UCPs: localization and functions
Denis Richard (Quebec, Canada)
SOCS proteins - negative regulators of the cytokine signal transduction
Warren Alexander (Victoria, Australia)
Role of Gab2 in allergic response
Benjamin Neel (Boston, USA)
UCP2 is a negative regulator of glucose-stimulated insulin secretion
Chen-yu Zhang (Boston, USA)
Uncoupling protein 3 and fatty acid metabolism
Abdul Dulloo (Fribourg, Switzerland)
The SAP/SLAM defence system
Cox Terhorst (Boston, USA)
11:00 - 11:30 Coffee Break,Trade exhibition and Poster Viewing
Mitochondrial uncoupling and lipid metabolism in adipocytes
Jan Kopecky (Prague, Czech Republic)
12:15 - 14:00 Lunch Break, Trade Exhibition and Poster Session
Perspectives on the biology of UCP homologues
Sean Adams (California, USA)
|
Signalling Homeostasis II
Chair:
Dr Melanie Welham (Bath)
Brain UCPs: localization and functions
Denis Richard (Quebec, Canada)
UCP2 is a negative regulator of glucose-stimulated insulin secretion
Chen-yu Zhang (Boston, USA)
Uncoupling protein 3 and fatty acid metabolism
Abdul Dulloo (Fribourg, Switzerland)
11:00 - 11:30 Coffee Break,Trade exhibition and Poster Viewing
Mitochondrial uncoupling and lipid metabolism in adipocytes
Jan Kopecky (Prague, Czech Republic)
Dr Tonks has been elected as a Fellow of the Royal Society and is unable to attend the Dublin Meeting. The Biochemical Society conveys warm congratulations to Dr Tonks
Nicholas K. Tonks - cancelled (New York, USA)
12:15 - 14:00 Lunch Break, Trade Exhibition and Poster Session
Perspectives on the biology of UCP homologues
Sean Adams (California, USA)
|
Teaching Practical Skills to 21st Century Biochemists
Biochemical Society Educational Group colloquium
Organizer:
Elizabeth Carrey (London, UK)
11:00 - 11:30 Coffee Break, Trade Exhibition and Poster Viewing
12:45 - 13:45 Lunch Break, Trade Exhibition and Poster Viewing
Adding function to structure in proteomics using SPR
Practical skills in Life Science
Practical biochemistry for preclinical medical students
Monika Löffler (Marburg, Germany)
15:15 - 16:45 Poster Session, Trade Exhibition and Tea Break
Acquiring the right techniques for biomedical analysis and clinical chemistry
David Perrett (London, UK)
Training the next generation of biochemists - projects, posters and posters
Practical molecular biology - large numbers on a small budget, a 21st Century paradox?
Nicola T. Hughes (Manchester, UK)
Honours projects - from plan to publication
Michael J.R.Stark (Dundee, UK)
Developing graduates in the pharmaceutical industry
Mark Edbrooke (Hertfordshire, UK)
11:00 - 11:30 Coffee Break,Trade exhibition and Poster Viewing
Specialist and refresher courses for the practising biochemist: the importance of continuing education
Andy Mee (Manchester, UK)
12:15 - 14:00 Lunch Break, Trade Exhibition and Poster Session
|
Enzymes That Regulate Lipid Metabolism in Cell Signalling
Molecular and Cellular Pharmacology and Lipid Groups
Organizers:
Sue Pyne (Strathclyde, UK)
Melanie Welham (Bath, UK)
Colin Macphee (Essex, UK)
Sponsors:
GlaxoSmithKline
New aspects of sphinolipids in relation to apoptosis
Wim van Blitterswijk (Amsterdam, The Netherlands)
Coordinate regulation of growth factor receptors and lipid phosphate phosphatase-1 control cell activation by exogenous lysophosphatidate
David Brindley (Alberta, Canada)
Regulation of de novo sphingolipid biosynthesis: a necessary but dangerous pathway
Alfred H.Merrill (Georgia, USA)
11:00 - 11:30 Coffee Break,Trade exhibition and Poster Viewing
Transactivation of the sphingosine-1-phosphate receptor EDG-1 is essential for PDGF-induced motility
Hans Rosenfeldt (Georgetown, USA)
12:15 - 14:00 Lunch Break, Trade Exhibition and Poster Session
Regulation of PLC-g and P13K pathways by adaptor proteins in B lymphocytes
Tomohiro Kurosaki (Osako, Japan)
SHIPs and their DOKs in regulation of lymphocyte function
John C. Cambier (Denver, USA)
Signalling via PI3 kinases
Phil Hawkins (Cambridge, UK)
Functional antagonism of PI 3-kinase signalling by the tumour suppressor protein, PTEN
Peter Downes (Dundee, UK)
|