Timetable
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Ribozymes and RNA Catalysis
Organizers:
David Lilley (Dundee, UK)
Fritz Eckstein (Göttingen, Germany)
Sponsors:
Major Sponsor - EMBO
The Transgenomic Lecture - Crystallographic snapshots of ribozyme catalysis
Bill Scott (Santa Cruz, CA, USA)
The hairpin ribozyme: from crystal structure to function
Adrian Ferré d'Amaré (Seattle, WA, USA)
10:20 - 11:00 Coffee break
Insights into hairpin ribozyme catalysis from studies of abasic variants
Marty Fedor (Scripps, CA, USA)
Hairpin and hammerhead ribozymes: How different are they?
John Burke (Vermont, USA)
The Glen Lecture - RNA-catalyzed RNA synthesis
David Bartel (Cambridge, MA, USA)
Mechanistic studies on ribozyme-catalysed carbon-carbon bond formation
Andres Jäschke (Berlin, Germany)
Engineering allosteric ribozymes
Ron Breaker (Yale, CT, USA)
10:15 - 11:00 Coffee break
The Qiagen Lecture - Real-time detection of molecular interactions through protein-responsive ribozymes
Michael Famulok (Bonn, Germany)
Optimization of intracellular ribozyme function
Jon Rossi (Beckman Research Institute, CA, USA)
The Dharmacon Lecture - Core architecture and mechanistic function of a group II intron
Anna Pyle (Columbia University, NY, USA)
Structural dynamics of the spliceosome
Reinhard Lürhmann (Göttingen, Germany)
Rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries
Group I introns and RNA folding
Eric Westhof (Strasbourg, France)
RNase P RNA-mediated catalysis
Leif Kirsebom (Uppsala, Sweden)
Function/structure analysis of the group I intron by chemical interference
Scott Strobel (Yale, CT, USA)
The Proligo Lecture - Structure and function of the large ribosomal subunit
Peter Moore (Yale, CT, USA)
09:40 - 10:20 Coffee break
Molecular RNP machines: the ribosome at work
Andrea Barta (Vienna, Austria)
Antibiotics binding to the ribosome
Ada Yonath (Hamburg, Germany)
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Evening
19:30 - 22:00 Reception at Botanic Gardens
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Ribozyme mechanisms
19:30 - 22:00 Reception at Botanic Gardens
The Glen Lecture - RNA-catalyzed RNA synthesis
David Bartel (Cambridge, MA, USA)
Mechanistic studies on ribozyme-catalysed carbon-carbon bond formation
Andres Jäschke (Berlin, Germany)
Engineering allosteric ribozymes
Ron Breaker (Yale, CT, USA)
10:15 - 11:00 Coffee break
The Qiagen Lecture - Real-time detection of molecular interactions through protein-responsive ribozymes
Michael Famulok (Bonn, Germany)
Optimization of intracellular ribozyme function
Jon Rossi (Beckman Research Institute, CA, USA)
The Dharmacon Lecture - Core architecture and mechanistic function of a group II intron
Anna Pyle (Columbia University, NY, USA)
Structural dynamics of the spliceosome
Reinhard Lürhmann (Göttingen, Germany)
Rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries
Group I introns and RNA folding
Eric Westhof (Strasbourg, France)
RNase P RNA-mediated catalysis
Leif Kirsebom (Uppsala, Sweden)
Function/structure analysis of the group I intron by chemical interference
Scott Strobel (Yale, CT, USA)
The Proligo Lecture - Structure and function of the large ribosomal subunit
Peter Moore (Yale, CT, USA)
09:40 - 10:20 Coffee break
Molecular RNP machines: the ribosome at work
Andrea Barta (Vienna, Austria)
Antibiotics binding to the ribosome
Ada Yonath (Hamburg, Germany)
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Morning
The Transgenomic Lecture - Crystallographic snapshots of ribozyme catalysis
Bill Scott (Santa Cruz, CA, USA)
The hairpin ribozyme: from crystal structure to function
Adrian Ferré d'Amaré (Seattle, WA, USA)
10:20 - 11:00 Coffee break
Insights into hairpin ribozyme catalysis from studies of abasic variants
Marty Fedor (Scripps, CA, USA)
Hairpin and hammerhead ribozymes: How different are they?
John Burke (Vermont, USA)
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Ribozyme mechanisms and folding
19:30 - 22:00 Reception at Botanic Gardens
The Transgenomic Lecture - Crystallographic snapshots of ribozyme catalysis
Bill Scott (Santa Cruz, CA, USA)
The hairpin ribozyme: from crystal structure to function
Adrian Ferré d'Amaré (Seattle, WA, USA)
10:20 - 11:00 Coffee break
Insights into hairpin ribozyme catalysis from studies of abasic variants
Marty Fedor (Scripps, CA, USA)
Hairpin and hammerhead ribozymes: How different are they?
John Burke (Vermont, USA)
The Glen Lecture - RNA-catalyzed RNA synthesis
David Bartel (Cambridge, MA, USA)
Mechanistic studies on ribozyme-catalysed carbon-carbon bond formation
Andres Jäschke (Berlin, Germany)
Engineering allosteric ribozymes
Ron Breaker (Yale, CT, USA)
10:15 - 11:00 Coffee break
The Qiagen Lecture - Real-time detection of molecular interactions through protein-responsive ribozymes
Michael Famulok (Bonn, Germany)
Optimization of intracellular ribozyme function
Jon Rossi (Beckman Research Institute, CA, USA)
The Nucleic Acids Award Lecture - The hammerhead ribozyme
Olke Uhlenbeck (Colorado, USA)
Catalysis by the Tetrahymena ribzoyme: Lessons learned
Dan Herschlag (Stanford, CA, USA)
The chemical mechanism of group I intron catalysis
Joe Piccirilli (Chicago, IL, USA)
Sequence and structural features responsible for determining cleavage rate in the Neurospora VS ribozyme
Rick Collins (Toronto, Canada)
The Dharmacon Lecture - Core architecture and mechanistic function of a group II intron
Anna Pyle (Columbia University, NY, USA)
Structural dynamics of the spliceosome
Reinhard Lürhmann (Göttingen, Germany)
Rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries
Group I introns and RNA folding
Eric Westhof (Strasbourg, France)
RNase P RNA-mediated catalysis
Leif Kirsebom (Uppsala, Sweden)
16:00 - 17:30 Selection of short oral presentations
Ribosome structure and clues to the mechanism of translation
Harry Noller (Santa Cruz, CA, USA)
Function/structure analysis of the group I intron by chemical interference
Scott Strobel (Yale, CT, USA)
The Proligo Lecture - Structure and function of the large ribosomal subunit
Peter Moore (Yale, CT, USA)
09:40 - 10:20 Coffee break
Molecular RNP machines: the ribosome at work
Andrea Barta (Vienna, Austria)
Antibiotics binding to the ribosome
Ada Yonath (Hamburg, Germany)
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Evening
16:00 - 17:30 Poster session 1
Ribozymes; 20 years later
Folding mechanisms of group I ribozymes
Sarah Woodson (Maryland, MD, USA)
The structure and active site of the VS ribozyme
David Lilley (Dundee, UK)
Folding of the td pre-RNA with the help of RNA chaperones
Renée Schroeder (Vienna, Austria)
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Selection and novel RNA-catalysed activity
19:30 - 22:00 Reception at Botanic Gardens
The Transgenomic Lecture - Crystallographic snapshots of ribozyme catalysis
Bill Scott (Santa Cruz, CA, USA)
The hairpin ribozyme: from crystal structure to function
Adrian Ferré d'Amaré (Seattle, WA, USA)
10:20 - 11:00 Coffee break
Insights into hairpin ribozyme catalysis from studies of abasic variants
Marty Fedor (Scripps, CA, USA)
Hairpin and hammerhead ribozymes: How different are they?
John Burke (Vermont, USA)
The Dharmacon Lecture - Core architecture and mechanistic function of a group II intron
Anna Pyle (Columbia University, NY, USA)
Structural dynamics of the spliceosome
Reinhard Lürhmann (Göttingen, Germany)
Rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries
Group I introns and RNA folding
Eric Westhof (Strasbourg, France)
RNase P RNA-mediated catalysis
Leif Kirsebom (Uppsala, Sweden)
Function/structure analysis of the group I intron by chemical interference
Scott Strobel (Yale, CT, USA)
The Proligo Lecture - Structure and function of the large ribosomal subunit
Peter Moore (Yale, CT, USA)
09:40 - 10:20 Coffee break
Molecular RNP machines: the ribosome at work
Andrea Barta (Vienna, Austria)
Antibiotics binding to the ribosome
Ada Yonath (Hamburg, Germany)
|
Morning
The Glen Lecture - RNA-catalyzed RNA synthesis
David Bartel (Cambridge, MA, USA)
Mechanistic studies on ribozyme-catalysed carbon-carbon bond formation
Andres Jäschke (Berlin, Germany)
Engineering allosteric ribozymes
Ron Breaker (Yale, CT, USA)
10:15 - 11:00 Coffee break
The Qiagen Lecture - Real-time detection of molecular interactions through protein-responsive ribozymes
Michael Famulok (Bonn, Germany)
Optimization of intracellular ribozyme function
Jon Rossi (Beckman Research Institute, CA, USA)
|
Ribozyme mechanisms
19:30 - 22:00 Reception at Botanic Gardens
The Transgenomic Lecture - Crystallographic snapshots of ribozyme catalysis
Bill Scott (Santa Cruz, CA, USA)
The hairpin ribozyme: from crystal structure to function
Adrian Ferré d'Amaré (Seattle, WA, USA)
10:20 - 11:00 Coffee break
Insights into hairpin ribozyme catalysis from studies of abasic variants
Marty Fedor (Scripps, CA, USA)
Hairpin and hammerhead ribozymes: How different are they?
John Burke (Vermont, USA)
Ribozymes; 20 years later
Folding mechanisms of group I ribozymes
Sarah Woodson (Maryland, MD, USA)
The structure and active site of the VS ribozyme
David Lilley (Dundee, UK)
Folding of the td pre-RNA with the help of RNA chaperones
Renée Schroeder (Vienna, Austria)
The Glen Lecture - RNA-catalyzed RNA synthesis
David Bartel (Cambridge, MA, USA)
Mechanistic studies on ribozyme-catalysed carbon-carbon bond formation
Andres Jäschke (Berlin, Germany)
Engineering allosteric ribozymes
Ron Breaker (Yale, CT, USA)
10:15 - 11:00 Coffee break
The Qiagen Lecture - Real-time detection of molecular interactions through protein-responsive ribozymes
Michael Famulok (Bonn, Germany)
Optimization of intracellular ribozyme function
Jon Rossi (Beckman Research Institute, CA, USA)
The Dharmacon Lecture - Core architecture and mechanistic function of a group II intron
Anna Pyle (Columbia University, NY, USA)
Structural dynamics of the spliceosome
Reinhard Lürhmann (Göttingen, Germany)
Rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries
Group I introns and RNA folding
Eric Westhof (Strasbourg, France)
RNase P RNA-mediated catalysis
Leif Kirsebom (Uppsala, Sweden)
16:00 - 17:30 Selection of short oral presentations
Ribosome structure and clues to the mechanism of translation
Harry Noller (Santa Cruz, CA, USA)
Function/structure analysis of the group I intron by chemical interference
Scott Strobel (Yale, CT, USA)
The Proligo Lecture - Structure and function of the large ribosomal subunit
Peter Moore (Yale, CT, USA)
09:40 - 10:20 Coffee break
Molecular RNP machines: the ribosome at work
Andrea Barta (Vienna, Austria)
Antibiotics binding to the ribosome
Ada Yonath (Hamburg, Germany)
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Evening
16:00 - 17:30 Poster session 2
The Nucleic Acids Award Lecture - The hammerhead ribozyme
Olke Uhlenbeck (Colorado, USA)
Catalysis by the Tetrahymena ribzoyme: Lessons learned
Dan Herschlag (Stanford, CA, USA)
The chemical mechanism of group I intron catalysis
Joe Piccirilli (Chicago, IL, USA)
Sequence and structural features responsible for determining cleavage rate in the Neurospora VS ribozyme
Rick Collins (Toronto, Canada)
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Group II introns and mRNA splicing; RNase P
19:30 - 22:00 Reception at Botanic Gardens
The Transgenomic Lecture - Crystallographic snapshots of ribozyme catalysis
Bill Scott (Santa Cruz, CA, USA)
The hairpin ribozyme: from crystal structure to function
Adrian Ferré d'Amaré (Seattle, WA, USA)
10:20 - 11:00 Coffee break
Insights into hairpin ribozyme catalysis from studies of abasic variants
Marty Fedor (Scripps, CA, USA)
Hairpin and hammerhead ribozymes: How different are they?
John Burke (Vermont, USA)
Ribozymes; 20 years later
Folding mechanisms of group I ribozymes
Sarah Woodson (Maryland, MD, USA)
The structure and active site of the VS ribozyme
David Lilley (Dundee, UK)
Folding of the td pre-RNA with the help of RNA chaperones
Renée Schroeder (Vienna, Austria)
The Glen Lecture - RNA-catalyzed RNA synthesis
David Bartel (Cambridge, MA, USA)
Mechanistic studies on ribozyme-catalysed carbon-carbon bond formation
Andres Jäschke (Berlin, Germany)
Engineering allosteric ribozymes
Ron Breaker (Yale, CT, USA)
10:15 - 11:00 Coffee break
The Qiagen Lecture - Real-time detection of molecular interactions through protein-responsive ribozymes
Michael Famulok (Bonn, Germany)
Optimization of intracellular ribozyme function
Jon Rossi (Beckman Research Institute, CA, USA)
The Nucleic Acids Award Lecture - The hammerhead ribozyme
Olke Uhlenbeck (Colorado, USA)
Catalysis by the Tetrahymena ribzoyme: Lessons learned
Dan Herschlag (Stanford, CA, USA)
The chemical mechanism of group I intron catalysis
Joe Piccirilli (Chicago, IL, USA)
Sequence and structural features responsible for determining cleavage rate in the Neurospora VS ribozyme
Rick Collins (Toronto, Canada)
Function/structure analysis of the group I intron by chemical interference
Scott Strobel (Yale, CT, USA)
The Proligo Lecture - Structure and function of the large ribosomal subunit
Peter Moore (Yale, CT, USA)
09:40 - 10:20 Coffee break
Molecular RNP machines: the ribosome at work
Andrea Barta (Vienna, Austria)
Antibiotics binding to the ribosome
Ada Yonath (Hamburg, Germany)
|
Morning
The Dharmacon Lecture - Core architecture and mechanistic function of a group II intron
Anna Pyle (Columbia University, NY, USA)
Structural dynamics of the spliceosome
Reinhard Lürhmann (Göttingen, Germany)
Rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries
Group I introns and RNA folding
Eric Westhof (Strasbourg, France)
RNase P RNA-mediated catalysis
Leif Kirsebom (Uppsala, Sweden)
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Afternoon
16:00 - 17:30 Selection of short oral presentations
Ribosome structure and clues to the mechanism of translation
Harry Noller (Santa Cruz, CA, USA)
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The ribosome
19:30 - 22:00 Reception at Botanic Gardens
The Transgenomic Lecture - Crystallographic snapshots of ribozyme catalysis
Bill Scott (Santa Cruz, CA, USA)
The hairpin ribozyme: from crystal structure to function
Adrian Ferré d'Amaré (Seattle, WA, USA)
10:20 - 11:00 Coffee break
Insights into hairpin ribozyme catalysis from studies of abasic variants
Marty Fedor (Scripps, CA, USA)
Hairpin and hammerhead ribozymes: How different are they?
John Burke (Vermont, USA)
The Glen Lecture - RNA-catalyzed RNA synthesis
David Bartel (Cambridge, MA, USA)
Mechanistic studies on ribozyme-catalysed carbon-carbon bond formation
Andres Jäschke (Berlin, Germany)
Engineering allosteric ribozymes
Ron Breaker (Yale, CT, USA)
10:15 - 11:00 Coffee break
The Qiagen Lecture - Real-time detection of molecular interactions through protein-responsive ribozymes
Michael Famulok (Bonn, Germany)
Optimization of intracellular ribozyme function
Jon Rossi (Beckman Research Institute, CA, USA)
The Dharmacon Lecture - Core architecture and mechanistic function of a group II intron
Anna Pyle (Columbia University, NY, USA)
Structural dynamics of the spliceosome
Reinhard Lürhmann (Göttingen, Germany)
Rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries
Group I introns and RNA folding
Eric Westhof (Strasbourg, France)
RNase P RNA-mediated catalysis
Leif Kirsebom (Uppsala, Sweden)
|
Morning
Function/structure analysis of the group I intron by chemical interference
Scott Strobel (Yale, CT, USA)
The Proligo Lecture - Structure and function of the large ribosomal subunit
Peter Moore (Yale, CT, USA)
09:40 - 10:20 Coffee break
Molecular RNP machines: the ribosome at work
Andrea Barta (Vienna, Austria)
Antibiotics binding to the ribosome
Ada Yonath (Hamburg, Germany)
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