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Toll-Like Receptors

3 February 2003

Novartis, Horsham, UK



Toll - Like Receptors

Organizers:
Steve Ward (Bath, UK)
Zarin Brown (Horsham, UK)
Luke O'Neill (Dublin, Ireland)
Sponsors:
AstraZeneca
The Biochemical Society
GlaxoSmithKline
Novartis Immunology Platform
Novartis Respiratory Diseases
Monday 3 February 2003
09:00 - 09:30 Registration

09:30 - 10:15
TLR family as adjuvant receptors
Shizuo Akira (Osaka, Japan)
10:15 - 11:00
Forward genetic analysis of the innate immune response
Bruce Beutler (Scripps, La Jolla, CA, USA)
11:00 - 11:30 Coffee Break

11:30 - 12:15
A genomic perspective on TLR signalling pathways
J. Fernando Bazan (DNAX Research Institute, USA)
12:15 - 13:00
Signal transduction pathways activated by toll-like receptors
Luke O'Neill (Dublin, Ireland)
13:00 - 14:15 Lunch & Poster Session

14:15 - 14:30
A toll-like receptor 7 (TLR7) specific stimulus uncovers strong relationship within the TLR7, 8 and 9 subfamily
Selected Poster Presentation - Stefan Bauer
14:30 - 14:45
The drosophila receptor toll-9 is structurally and functionally related to mammalian TLRs
Selected Poster Presentation - Hana Bilak
14:45 - 15:00
Toll-like receptor 4 polymorphisms and the systemic inflammatory response syndrome
Selected Poster Presentation - Nicholas Child
15:00 - 15:15
CpG DNA recognition: overriding species specificity with novel synthetic motifs
Selected Poster Presentation - Ekambar Kandimalla
15:15 - 16:00
Structural aspects of toll receptors
Nick Gay (Cambridge, UK)
16:00 - 16:30 Coffee Break

16:30 - 17:15
Toll-like receptors, CD14 and MD2
Douglas Golenbock (Massachusetts, USA)
17:15 - 18:00
Discrimination of different LPS types by TLRs
Stefanie Vogel (Bethseda, MD, USA)
18:00 - 19:00
Drinks Reception