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Intermolecular Associations in 2D and 3D

19—20 June 2003

University of Nottingham



Organizers:
Steve Harding (Nottingham, UK)
Paul O'Shea (Nottingham, UK)

Timetable

Thursday 19 June 2003Friday 20 June 2003
10:30 - 16:30
Structure and Spectroscopic Probes

09:00 - 10:30
Hydrodynamic and Calorimetric Probes

11:00 - 16:30
Application to Specific Systems


Structure and Spectroscopic Probes

Thursday 19 June 2003
09:00 - 10:30 Registration and Coffee/Tea

10:30 - 11:00
X-ray crystallographic studies of protein ligand interactions
Rex Palmer (London, UK)
11:00 - 11:30
Molecular modelling probes
Romano Kroemer (Milan, Italy)
11:30 - 12:00
Protein-ligand and protein-protein interactions studied by electrospray ionisation and mass spectrometry
Peter Derrick (Warwick, UK)
12:00 - 12:30
Intermolecular interactions in membrane systems; new molecular probes, spectroscopies, and optical technologies for ¿next generation¿ biological imaging
Paul O'Shea (Nottingham, UK)
12:30 - 14:00 Lunch and poster session

14:00 - 14:30
Scanning FCS
Enrico Gratton (Illinois, USA)
14:30 - 15:00
Interprotein interactions are responsible for the confined diffusion of a G protein coupled receptor at the cell surface
Laurence Salomé (IPBS-CNRS, Toulouse, France)
15:00 - 15:30 Coffee/tea break

15:30 - 16:00
NMR studies of protein-ligand interactions
Iain Campbell (Oxford, UK)
16:00 - 16:30
Measuring and visualizing single molecular interactions in biology; investigations of macromolecule-membrane interactions
Stephanie Allen (Nottingham, UK)
19:30 Meeting Dinner (Council Dining Room, Trent Building)

Hydrodynamic and Calorimetric Probes

Friday 20 June 2003
09:00 - 09:30
The development of chromatography for the determination of protein interactions: a personal perspective
Don Winzor (Brisbane, Australia)
09:30 - 10:00
Tracer sedimentation equilibrium: a powerful tool for the quantitative characterization of macromolecular self- and hetero-associations in solution
Allen Minton (NIH, Bethesda, MD, USA)
10:00 - 10:30
Calorimetric probes of intermolecular association
Babur Chowdhry (Greenwich, UK)
10:30 - 11:00 Coffee/tea break

Application to Specific Systems

Friday 20 June 2003
11:00 - 11:30
Studying ligand-receptor interaction in unordered, biologically active membranes at atomic resolution
Anthony Watts (Oxford, UK)
11:30 - 12:00
Signalling interactions in cells and membranes
Thomas Jovin (Max Planck Inst Biophys Chem, Göttingen, Germany)
12:00 - 12:30
Measurements of associations of cell surface receptors by single particle fluorescence imaging
Richard Cherry (Essex, UK)
12:30 - 13:30 Lunch

13:30 - 14:00
Cell-surface recognition by T cells
Anton van der Merwe (Oxford, UK)
14:00 - 14:30
Binding properties and anti-bacterial activities of V-region identical, human IgG and IgM antibodies, against group B Neisseria meningitidis
Terje Michaelsen (Oslo, Norway)
14:30 - 15:00 Coffee/tea break

15:00 - 15:30
Mucoadhesive interactions
Stephen Harding (Nottingham, UK)
15:30 - 16:00
The androgen receptor transactivation domain: the interplay between protein conformation and protein-protein interactions
Iain McEwan (Aberdeen, UK)
16:00 - 16:30
Single molecule mechanics of Myo1c: a molecular motor involved in mammalian mechano-sensing
Justin Molloy (NIMR, London, UK)