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Unravelling Nature's Networks: from Microarray and Proteomic Analysis to Systems Biology

20—22 July 2003

University of Sheffield, UK



Unravelling Nature's Networks: from Microarray and Proteomic Analysis to Systems Biology

Organizers:
Nick Monk (Sheffield, UK)
Neil Lawrence (Sheffield, UK)
Sponsors:
The Centre for Bioinformatics and Computational Biology, University of Sheffield
Pfizer

Data Acquisition

Monday 21 July 2003
09:00 - 09:30 Registration and coffee

09:30 - 09:40
Introduction
Matthew Holley (Sheffield, UK)
09:40 - 10:20
Functional genomics of inflammatory signalling
Steve Dower (Sheffield, UK)
10:20 - 10:40
Systems biology markup language: Level 2 and beyond
Selected Poster Presentation - Andrew Finney (Hertfordshire, UK)
10:40 - 11:00
Control analysis of microarray data
Selected Poster Presentation - R. Keira Curtis (Cambridge, UK)
11:00 - 11:30 Coffee/tea break

11:30 - 12:10
Defining the transcriptional regulatory networks underlying development of the mouse forebrain
Rick Livesey (Cambridge, UK)
12:10 - 12:30
Interpreting correlations in metabolic networks
Selected Poster Presentation - Ralf Steuer (Potsdam, Germany)
12:30 - 14:00 Lunch

Data Analysis

Monday 21 July 2003
12:30 - 14:00 Lunch

14:00 - 14:40
Feature selection in functional classification of micro-array gene expression data
Mahesan Niranjan (Sheffield, UK)
14:40 - 15:20
Mining a tandem mass spectrometry database
Terry Speed (Parkville, Australia)
15:20 - 15:45 Coffee/tea break

15:45 - 16:25
Functional annotation and data quality assessment through integrated analysis of genome-scale data
Patrick Kemmeren (Utrecht, Netherlands)
16:25 - 16:45
Surrogate markers to determine drug activity
Selected Poster Presentation - Carol McClelland (Kent, UK)
16:45 - 18:00 Poster session and refreshments

From Data to Networks

Tuesday 22 July 2003
09:00 - 09:40
Yeast two-hybrid protein-protein interactions don't live in a small world
Alun Thomas (Utah, UT, USA)
09:40 - 10:20
Supervised classification for gene network reconstruction
Lev Soinov (Hinxton, UK)
10:20 - 11:00
Analysis and Modelling of Signal Transduction Pathways in Systems Biology
Kwang-Hyun Cho (UMIST, UK)
11:00 - 11:30 Coffee/tea break

11:30 - 11:50
A probablistic model for the extraction of expression levels from oligonucleotide arrays
Selected Poster Presentation - Marta Milo (Sheffield, UK)
11:50 - 12:10
A petri net framework for the representation of biological knowledge
Selected Poster Presentation - John Pinney (Leeds, UK)
12:10 - 12:30
Bayesian networks
Selected Poster presentation - Dirk Husmeier (Edinburgh, UK)
12:30 - 14:00 Lunch

Modelling Interaction Networks

Tuesday 22 July 2003
12:30 - 14:00 Lunch

14:00 - 14:40
Reconstructing Gene Networks: What Are the Limits?
Jaroslav Stark (Imperial College, London, UK)
14:40 - 15:20
Modelling the controls of the eukaryotic cell cycle
Béla Novák (Budapest, Hungary)
15:20 - 16:00
Integration of data, mathematical models and software for cell and developmental simulation
Eric Mjolsness (California, CA, USA)
16:00 Close of meeting