Chair:
Professor Ivan Roitt (UCL, London, UK)
Ian Dransfield (Edinburgh, UK)
09:00 - 10:00 Registration and tea/coffee
Chaperonin structure and function
Mechanisms of substrate recognition by HSP70 chaperones
Peptides complexed to HSP70 generate efficient human CTL responses
Paul Lehner - Selected poster presentation (Cambridge, UK)
Vaccination with mycobacterial heat shock protein complexes induces interferon gamma and provides protection in the murine aerosol challenge model of TB
Camilo Colaco - Selected poster presentation (ImmunoBiology Limited, Cambridge, UK)
Heat shock protein and the art of immunological maintenence
12:30 - 14:00 Lunch and poster session
Functional properties of HSP70: characterization of epitopes which immunomodulate cytokines, chemokines and dendritic cell maturation
Tom Lehner (Kings College, London, UK)
Involvement of LOX-1 in Hsp70-mediated antigen cross-presentation
Yves Delneste (INSERM, Angers, France)
15:20 - 15:50 Coffee / tea break
Heat shock proteins in innate immunity
Functional domain mapping of the HSP70 cochaperone HSJ1
Paul Chapple - Selected poster presentation (UCL, London, UK)
The LCA associated protein AIPL1 modulates NUB1
Jacqueline van der Spuy - Selected poster presentation (UCL, London, UK)
17:00 Robens suite bar open
Timetable TBC