Organizers:
Rhona Borts (University of Leicester, UK)
Adam Eyre Walker (University of Sussex, UK)
Alastair Goldman (University of Sheffield, UK)
Gil McVean (University of Oxford, UK)
Marshall Stark (University of Glasgow, UK)
Deborah Charlesworth (University of Edinburgh, UK)
Graham Moore (John Innes Centre, UK)
Timetable
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Hotspots: distribution and characterization
Chair:
Graham Moore (John Innes Centre, UK)
Gil McVean (University of Oxford, UK)
Why have sex? The population genetics of sex and recombination
Plenary Speaker - Sally Otto (University of British Columbia, Canada)
Mitotic and meiotic recombination in yeast: hotspots and coldspots
Tom Petes (University of North Carolina, USA)
Control of resection and recombination at Spo11 double-strand breaks
Matthew Neale (Memorial Sloan-Kettering Cancer Center, New York, USA)
15:50 - 16:20 Coffee/Tea Break
The distribution of recombination in the human genome
Gil McVean (University of Oxford, UK)
Meiotic hot spots of recombination in plants
Christine Mezard (CNRS, France)
Genetics Society Promega Young Geneticist of the Year Award
20:00 - 22:00 Poster session and cheese and wine reception
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Gene conversion and crossing over
Chair:
Marshall Stark (University of Glasgow, UK)
Control of the crossover outcome of meiotic recombination
Michael Lichten (National Cancer Institute, USA)
Sgs1p and Msh6p prevent inappropriate recombination in S.cerevisiae
Selected oral communication - Alexandre Chaix (University of Leicester)
Human polymorphism around recombination hotspots
Selected oral communication - Chris Spencer (University of Oxford, UK)
Pathways of crossing over
Matt Whitby (University of Oxford, UK)
10:40 - 11:10 Coffee/tea break
Crossover and noncrossover pathways in mouse meiosis.
Bernard De Massy (CNRS, France)
The use of a VDE reporter cassette for the study of double strand breaks in meiosis
Selected oral communication - Rebecca Johnson (University of Sheffield, UK)
Crossover proteins influence the segregation of non-exchange chromosome pairs
Eva R Hoffmann (University of Sussex, UK)
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Chromosome dynamics in meiosis
Chair:
Maj Hulten (University of Warwick, UK)
Maize mutants that regulate leptotene chromosome structure and function
Zac Cande (University of California ¿ Berkeley, USA)
Control of meiotic recombination in Arabidopsis: the role of the MutL/S homologues
Selected oral communication - Chris Franklin (University of Birmingham, UK)
Using high-throughput data to imply gene function: Assessment of selected genes for roles in meiotic and mitotic DNA processing
Selected oral communication - Philip Jordan (University of Edinburgh, UK)
Modulation of meiotic telomere dynamics
Harry Scherthan (Max-Planck-Institut fur Molekulare Genetik, Germany)
15:30 - 16:00 Coffee/tea break
How do cells hold sister chromatids together during mitosis and meiosis?
Kim Nasmyth (University of Oxford, UK)
Coordinate control of chromosome morphogenesis and Holliday junction resolution during meiosis
Selected oral communication - Valentin Boerner (Cleveland State University, USA)
Analysis of a genetic cross between fluorescent trypanosomes
Selected oral communication - Wendy Gibson (University of Bristol, UK)
Unravelling the 50 year old Ph1 puzzle in wheat
Graham Moore (John Innes Centre, UK)
Genetics Society Balfour Lecture
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Meiotic drive
Chair:
Brian Charlesworth (University of Edinburgh, UK)
Polymorphism and evolution of human meiotic recombination hot spots
Alec Jeffreys (University of Leicester, UK)
Live hot, die young: transmission distortion in recombination hotspots
Selected oral communication - Graham Coop (University of Chicago, USA)
Effects of intra-gene epistasis on the benefit of sexual recombination
Selected oral communication - Richard Watson (University of Southampton, UK)
Sex-ratio meiotic drive in Drosophila simulans: cellular mechanism and candidate genes
Catherine Montchamp-Moreau (CNRS, France)
10:40 - 11:10 Coffee/tea break
The maize abnormal chromosome 10 meiotic drive system
Kelly Dawe (University of Georgia, Georgia, USA)
Molecular evolution of X-chromosome drive in Drosophila recens
Selected oral communication - Kelly Dyer (University of Edinburgh, UK)
Why Mendelian segregation?
Selected oral communication - Francisco Ubeda (University of Oxford, UK)
Genetic conflicts during meiosis and the evolutionary origins of centromere complexity
Harmit Malik (Fred Hutchinson Cancer Research Center, USA)
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When mammalian meiosis goes wrong
Chair:
Alastair Goldman (University of Sheffield, UK)
Meiosis in mammals: recombination, nondisjunction and the environment
Pat Hunt (Washington State University, USA)
Relationship of recombination patterns and maternal age among nondisjoined chromosomes 21
Stephanie Sherman (Emory University, USA)
15:10 - 15:40 Coffee/tea break
Is the silencing of unsynapsed chromosomes in mammalian meiosis a response to unrepaired DNA double strand breaks?
Paul Burgoyne (MRC National Institute for Medical Research, UK)
Telomere instability and variation in the male germline
Selected oral communication - Bethan Britt Compton (University of Cardiff, UK)
Sequence motifs and human recombination hotspots
Selected oral communication - Simon Myers ( Broad Institute of Harvard and MIT, Massachusetts, USA)
Mitotic checkpoint proteins in meiosis and infertility
Jan van Deursen (Mayo Clinic, USA)
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