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Non-vesicular intracellular traffic

15—16 December 2005

Goodenough College, London, UK



Chairs:
Tim Levine (Institute of Ophthalmology, UK)
Karel Wirtz (Utrecht University, Netherlands)
Dennis Voelker (National Jewish Medical Research Center, USA)
Fred Maxfield (Cornell University, USA)
Dennis Vance (University of Alberta, USA)
Shamshad Cockcroft (University College London, UK)
Organizers:
Shamshad Cockcroft (University College London, UK)
Tim Levine (Institute of Ophthalmology, UK)
Thursday 15 December 2005
08:15 - 09:00 Registration with coffee/tea

09:00 - 09:40
Intracellular distribution and transport of DHE, a fluorescent sterol
Fred Maxfield (Cornell University, USA)
09:40 - 10:20
The ER-mitochondria calcium cross-talk: mechanisms and roles
Rosario Rizzuto (University of Ferrara, Italy)
10:20 - 10:40
Structure and function of nucleus-vacuole junctions in saccharomyces cerevisiae
Selected oral communication - David Goldfarb (University of Rochester, USA)
10:40 - 11:00
MLN64 and MENTHO, two mediators of endosomal cholesterol transport
Selected oral communication - Fabien Alpy (Univeristy of Strasbourg, France)
11:00 - 11:30 Coffee/tea break

11:30 - 12:10
Genetic models and study of the physiological functions of phosphatidylinositol transfer proteins
Vytas Bankaitis (University of North Carolina at Chapel Hill, USA)
12:10 - 12:30
Mitochondrial localisation regulates calcium entry, but not ER calcium release
Selected oral communication - Guy Rutter (University of Bristol, UK)
12:30 - 13:10
Sterol trafficking between the endoplasmic reticulum and plasma membrane in yeast
Anant Menon (Cornell University, USA)
13:10 - 14:10 Lunch

14:10 - 15:40 Poster session and coffee/tea

15:40 - 16:20
Uptake and trafficking of exogenous sterol in Saccharomyces cerevisiae
Will Prinz (National Institute of Diabetes and Digestive and Kidney Diseases, USA)
16:20 - 17:00
Lipid homeostasis and Golgi secretory function
Sima Lev (Weizmann Institute of Science, Israel)
17:00 - 17:40
Characterization of dihydroceramide synthase from yeast; subunit structure and topology
Howard Riezman (University of Geneva, Switzerland)
Friday 16 December 2005
08:50 - 09:30
Interaction of smooth endoplasmic reticulum and mitochondria
I. Robert Nabi (University of British Columbia, Canada)
09:30 - 09:50
Annexin-dependent rafts act as Ca2+-sensing feedback loops for the regulation of intracellular Ca2+-homeostasis
Selected oral communication - Annette Draeger (University of Bern, Switzerland)
09:50 - 10:30
Phosphatidylinositol transfer protein and its homologues in yeast
Peter Griac (Slovak Academy of Sciences, Slovak Republic)
10:30 - 11:00 Coffee/tea break

11:00 - 11:40
Movement of calcium signals and calcium binding proteins - firewalls, traps and tunnels
Alexei Tepikin (University of Liverpool, UK)
11:40 - 12:00
ER-bounded calcium microdomains during mitosis
Selected oral communication - Michael Whitaker (University of Newcastle-upon-Tyne, UK)
12:00 - 12:20
The human OSBP-related proteins (ORPs) ¿ sterol sensors that coordinate lipid metabolism?
Selected oral communication - Vesa Olkkonen (National Public Health Institute, Finland)
12:20 - 13:00
Endosomal cholesterol traffic: vesicular and non-vesicular mechanisms meet
Elina Ikonen (University of Helsinki, Finland)
13:00 - 14:00 Lunch

14:00 - 14:40
Lipid trafficking between the endoplasmic reticulum and the chloroplast
Christoph Benning (Michigan State University, USA)
14:40 - 15:20
Lipid dynamics in neurons
Jean Vance (University of Alberta, Canada)
15:20 - 16:00
Macromolecular assemblies regulate non-vesicular PtdSer traffic in yeast
Dennis Voelker (National Jewish Medical Research Center, USA)
16:00 - 18:00 Drinks reception and discussion session