Organizers:
Kathleen Botham (Royal Veterinary College, London, UK)
Caroline Wheeler-Jones (Royal Veterinary College, London, UK)
Timetable
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Chylomicron remnants and cardiovascular disease
Chair:
Kathleen Botham and Caroline Wheeler-Jones (Royal Veterinary College, London, UK)
11:00 - 14:00 Registration
14:00 - 14:15 Welcome from Professor Jonathan Elliott, Vice-Principal for Research
Chylomicrons as a risk factor for atherosclerosis and Alzheimer's disease
John Mamo (Curtin University of Technology, Australia)
15:15 - 15:45 Coffee/tea break
Human chylomicron remnants induce the adhesion of monocytes to endothelial cells and this effect is greater with delayed remnant removal
Allen Cooper (Stanford University, USA)
Post-prandial lipoproteins and thrombosis
Tom Sanders (King's College London, UK)
Comparison of the effects of dietary saturated, monounsaturated, and polyunsaturated fatty acids on very low density lipoprotein secretion when delivered to hepatocytes in chylomicron remnant-like particles
Selected oral communication - Iliana Lopez-Soldado (Royal Veterinary College, London, UK)
17:10 - 19:00 Drinks reception and poster session
19:30 - 22:00 Meeting dinner
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Chylomicron remnants and endothelial dysfunction
Chair:
Caroline Wheeler-Jones (Royal Veterinary College, London, UK)
Chylomicron remnants: mediators of endothelial dysfunction?
Caroline Wheeler-Jones (Royal Veterinary College, London, UK)
Postprandial inflammation and endothelial dysfunction.
Manuel Castro Cabezas (Saint Franciscus Gasthuis, The Netherlands)
Modulation of the effects of chylomicron remnants on endothelial function by minor dietary lipid components
Javier S Perona (Consejo Superior de Investigaciones Científicas, Spain)
Meal fatty acids influence postprandial vascular reactivity
Selected oral communication - Kim Jackson (University of Reading, UK)
10:45 - 11:15 Coffee/tea break
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Chylomicron remnants and macrophage function
Chair:
Kathleen Botham (Royal Veterinary College, UK)
The induction of macrophage foam cells by chylomicron remnants
Kathleen Botham (Royal Veterinary College, London, UK)
Mechanisms involved in chylomicron remnant lipid uptake by macrophages
Elena Bravo (Istituto Superiore di Sanità, Italy)
Dietary fats induce human monocyte activation in vitro
Selected oral communication - Charlotte Lawson (Royal Veterinary College, London, UK)
Postprandial leukocyte activation: a mechanism for atherosclerosis and inflammation by triglyceride rich lipoproteins
Selected oral communication - Arash Alipour (St Franciscus Gasthuis, The Netherlands)
The modification of triacylglycerol-rich lipoproteins fatty acid composition by minor components of pomace olive oil leads to increased mRNA expression of scavenger receptors in macrophages.
Selected oral communication - Rosana Cabello-Moruno (Instituto de la Grasa (CSIC), Spain)
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Chylomicron remnants and obesity, diabetes and the metabolic syndrome
Chair:
Spencer Proctor (University of Alberta, Canada)
Chylomicron, chylomicron remnant and VLDL metabolism in the metabolic syndrome
Fredrik Karpe (University of Oxford, UK)
Chylomicron and apoB 48 metabolism in the JCR:LA corpulent rat, a model for the metabolic syndrome
Spencer Proctor - sponsored by Merck (University of Alberta, Canada)
Measurement of endogenous and exogenous triglyceride kinetics in the fed and fasted state
Selected oral communication - Feifei Sun (University of Surrey, UK)
Apolipoprotein B48, insulin resistance, dyslipidemia and visceral fat in overweight pre-pubertal children
Selected oral communication - Ugo Nzekwu (University of Alberta, Canada)
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