Organizers:
David Allsop (University of Lancaster, UK)
Harry McArdle (Rowett Institute, UK)
09:00 - 10:00 Registration
Copper transport in human cells: the role of Cu-transporting ATPases
Svetlana Lutsenko (University of Oregon, USA)
Role of Dcytb in iron metabolism: an update
Andrew McKie (King¿s College London, UK)
Imaging iron influx and iron-induced toxicity in neurons and astrocytes
Selected oral communication - Ilaria Pelizzoni (HSR Scientific Institute, Italy)
Regulation and function of Zip4, the acrodermatitis enteropathica gene
Glen Andrews (University of Kansas Medical Center, USA)
12:00 - 14:00 Lunch and poster session
Zinc regulation in a model vertebrate, the zebrafish
Christer Hogstrand (King's College London, UK)
Novel Drosophila mutants with discrepancies in iron metabolism
Selected oral communication - Abhyuday Deshpande (Queen Mary University of London, UK)
Interactions between iron and copper in development
Lorraine Gambling (Rowett Research Institute, UK)
15:25 - 16:00 Coffee/tea break
Mechanisms of mammalian zinc-regulated gene expression
Dianne Ford (University of Newcastle, UK)
Albumin as a zinc carrier - properties of its high-affinity zinc-binding site
Selected oral communication - Claudia Blindauer (University of Warwick, UK)
The role of iron in neurodevelopment
Michael Georgieff (University of Minnesota, USA)
17:30 - 19:00 Drinks reception
19:30 - 21:00 Meeting dinner
Prion protein and metal metabolism
Nigel Hooper (University of Leeds, UK)
Altered cellular zinc homeostasis contributes to pathology in Niemann-Pick type C disease, a neurodegenerative lysosomal storage disorder
Selected oral communication - Emyr Lloyd-Evans (University of Oxford, UK)
Ceruloplasmin in neurodegenerative diseases
Zena Leah Harris (John Hopkins University, USA)
10:25 - 11:00 Coffee/tea break
Iron and the translation of the amyloid precursor protein and ferritin; riboregulation against neural oxidative damage in Alzheimer's disease
Jack Rogers (Harvard Medical School, USA)
COMMD1 as a novel regulator of SOD1 activity and aggregation in amyotrophic lateral sclerosis
Selected oral communication - Willianne Vonk (University Medical Centre Utrecht, the Netherlands)
Metal metabolism is linked to key proteins in Alzheimer¿s disease
Gerd Multhaup (Free University of Berlin, Germany)
12:25 - 14:30 Lunch and poster session
Generation of reactive oxygen species from amyloidogenic proteins
David Allsop (University of Lancaster, UK)
Regulation and activity of metal binding proteins involved in neurodegeneration
David Brown (University of Bath, UK)
Iron chelation as a potential therapy for neurodegenerative disease
Bob Hider (King's College London, UK)