Organizers:
Malcolm White (University of St Andrews, UK)
Stephen Bell (University of Oxford, UK)
12:00 - 14:00 Registration and lunch
Timetable
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DNA replication
Chair:
Malcolm White (University of St Andrews, UK)
Cell cycle events in Sulfolobus
Stephen Bell (University of Oxford, UK)
DNA replication in methanogens
James Chong (University of York, UK)
A comparison of the Methanothermobacter thermautotrophicus and Thermoplasma acidophilum MCM helicases
Zvi Kelman (University of Maryland, USA)
15:30 - 16:00 Coffee/tea break
Structure and mechanism of an archaeal replication origin binding protein
Dale Wigley (Cancer Research, UK)
Structure and function of key players of the archaeal replication machinery
Satish Nair (University of Illinois, USA)
Reverse genetic analysis of an archaeal MCM
Selected oral communication - Stuart MacNeill (University of Copenhagen, Denmark)
17:15 - 19:00 Opening reception and poster session 1
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Transcription and cell cycle
Chair:
Roger Garrett (University of Copenhagen, Denmark)
Molecular mechanisms of Archaeal RNA polymerase
Finn Werner (University College London, UK)
Analysis of eukaryotic archaeal hybrid RNA polymerases
Michael Thomm (University of Regensburg, Germany)
Unravelling the role of Alba in the organization of the archaeal nucleoid
Remus Dame (Vrije Universiteit Amsterdam)
10:30 - 11:00 Coffee/tea break
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Genomics and evolution
Chair:
Peter Lund (University of Birmingham, UK)
Structural and functional interplay between chromosomes, viruses and plasmids of the acidothermophilic crenarchaeal order Sulfolobales
Roger Garrett (University of Copenhagen, Denmark)
The universal Kae1 protein family and the archaeal/eukaryal KEOPS complex: a mysterious protein network essential for genome integrity in the three domains
Patrick Forterre (Pasteur Institute, France)
12:00 - 13:15 Lunch and poster session 2
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Microbiology
Chair:
Thorsten Allers (University of Nottingham, UK)
Development of an infectious clone of Sulfolobus turreted icosahedral virus
Selected oral communication - Jennifer Fulton (Montana State University, USA)
Responses of the hyperthermophilic archaeon Sulfolobus solfataricus to UV irradiation
Christa Schleper (University of Vienna, Austria)
Replication of the plasmid pRN1 from Sulfolobus islandicus
Georg Lipps (University of Bayreuth, Germany)
Nicola Abrescia (University of Oxford, UK)
Biochemical, structural and cellular characterization of ESCRT-III-like components in Sulfolobus solfataricus
Selected oral communication - Cedric Hobel (Max-Planck Institute for Developmental Biology, Germany)
Role of vapBC Toxin-Antitoxin loci in the thermal stress response of the hyperthermophilic crenarchaeon Sulfolobus solfataricus
Selected oral communication - Charlotte Cooper (North Carolina State University, USA)
15:30 - 16:00 Coffee/tea break
Analysis of chaperone function in the archaeon Haloferax volcanii
Peter Lund (University of Birmingham, UK)
Small CRISPR RNAs guide anti-viral defense in prokaryotes
John van der Oost (Wageningen University, The Netherlands)
SulfoSYS: Silicon Cell Model for the central carbohydrate metabolism of the archaeon Sulfolobus solfataricus under temperature variation
Bettina Siebers (University of Duisburg-Essen, Germany)
On the interaction of Nanoarchaeum equitans with Ignicoccus hospitalis: proteins in the gap between two cells
Selected oral communication - Reinhard Rachel (University of Regensburg, Germany)
19:00 - 22:00 Conference Dinner and ceilidh
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DNA repair
Chair:
Steve Bell (University of Oxford, UK)
Recognition of deaminated bases by archaeal family B DNA polymerases: high resolution structural data and role in DNA repair
Bernard Connolly (University of Newcastle, UK)
DNA topoisomerases and genome stability
Maria Ciaramella (CNR, Italy)
Actions of Archaeal Hel308 Helicase
Edward Bolt (University of Nottingham, UK)
10:30 - 11:00 Coffee/tea break
Structure and function of archaeal DNA repair proteins
Malcolm White (University of St Andrews, UK)
Structural and biochemical mechanisms of RNA degradation by the archaeal exosome
Karl-Peter Hopfner (University of Munich, Germany)
Structural and functional studies of a novel archaeal DNA repair endonuclease using a co-operative molecular regulatory mechanism
Selected oral communication - Hannu Myllykallio (IGM, U. Paris-Sud, France)
12:15 - 13:15 Lunch and poster session 3
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Genetics and recombination
Chair:
John van der Oost (Wageningen University, The Netherlands)
Small RNAs from the halophilic archaeon Haloferax volcanii
Selected oral communication - Jorg Soppa (University of Frankfurt, Germany)
Homologous recombination in Sulfolobus acidocaldarius: genetic assays and functional properties
Dennis Grogan (University of Cincinnati, USA)
Sulfolobus genetic systems
Qunxin She (Copenhagen University, Denmark)
Genetic tools and their application in Sulfolobus solfataricus
Sonja Albers (University of Groningen, The Netherlands)
RadB, a paralogue of RadA, is a mediator of homologous recombination in Haloferax volcanii
Thorsten Allers (University of Nottingham, UK)
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