Organizers:
Nigel Scrutton (Manchester Interdisciplinary Biocentre, UK)
Andrew Munro (Manchester Interdisciplinary Biocentre, UK)
09:00 - 10:30 Registration and coffee/tea
The mechanisms of coenzyme B12 dependent enzymes: insights from rapid reaction studies on glutamate mutase
Neil Marsh (University of Michigan, USA)
Evaluating the mechanisms of redox reactions catalysed by complex I using kinetic simulations: a combination of modern and traditional approaches
The effect of temperature dependence of internal friction on enzyme reaction parameters under native reaction conditions
Andras Malnasi-Csizmadia (University of Eotvos, Hungary)
12:30 - 14:00 Lunch and poster session (odd numbered posters)
An end to 40 years of mistakes in DNA-protein association kinetics?
Stephen Halford (University of Bristol, UK)
Probing coupled motions in enzymatic hydrogen tunnelling reactions
Rudolf Allemann (University of Cardiff, UK)
Laser-induced hydrogen transfer reactions in a light-activated enzyme
Derren Heyes (University of Manchester, UK)
Kinetics and mechanism of CB1954 reduction by E.coli nitroreductase
Selected oral communication - Andrew Christofferson (University of Birmingham)
16:10 - 16:40 Coffee and tea
Time resolved studies of radical pairs
Jonny Woodward (Tokyo Institute of Technology, Japan)
Linking computational and experimental enzymology
Adrian Mulholland (University of Bristol, UK)
18:00 - 19:30 Drinks reception and poster session
19:30 - 22:00 Conference Dinner
Spectroelectrochemical studies of a multi-heme cytochrome
Julea Butt (University of East Anglia, UK)
The mechanism of oxygen activation of L-arginine by nitric oxide synthase enzymes, a theoretical study
Samuel de Visser (University of Manchester, UK)
10:20 - 10:50 Coffee and tea
Combining X-ray crystallography and single crystal spectroscopy to probe enzyme mechanisms
Arwen Pearson (University of Leeds, UK)
Magnetic resonance studies on reaction mechnisms of blue-light active Proteins
Stefan Weber (University of Freiburg, Germany)
Ultrafast events in catalysis studied with transient absorption spectroscopy
Marloes Groot (Free University, The Netherlands)
Oxacarbenium ion intermediates in enzyme catalyzed glycoside hydrolysis
Selected oral communication - Ian Greig (University of Bath, UK)
13:00 - 14:00 Lunch and poster session (even numbered posters)
The bacterial nitric oxide reductase
Nick Watmough (University of East Anglia, UK)
Structure and dynamics in purple bacterial reaction centres
Mike Jones (University of Bristol, UK)
Oxidation of L-tryptophan in biology
Emma Raven (University of Leicester, UK)