Organizers:
Michael Sternberg (Imperial College London, UK)
Janet Thornton (EMBL-EBI Wellcome Trust Genome, UK)
Roman Laskowski (EMBL-EBI Wellcome Trust Genome, UK)
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Protein Sequence, structure and function
Chair:
Michael Sternberg (Imperial College London, UK)
10:00 - 11:30 Registration (with coffee/tea)
Janet Thornton (EMBL-EBI Wellcome Trust Genome, UK)
Structural and functional restraints in the evolution of protein families and superfamilies
Tom Blundell (University of Cambridge, UK)
Separating derived from ancestral features of the mouse and the human genomes
Chris Ponting (MRC, University of Oxford, UK)
Multi-substrate-activity space and quasi-species in enzyme evolution
Bengt Mannervik (Uppsala University, Sweden)
Phylogenetic analysis of haem peroxidases and catalases reveals the occurrence of unknown enzyme (sub)families
Selected oral communication - Marcel Zamocky (University of Natural Resources and Applied Life Sciences, Austria)
Evolution of primate orphan proteins
Selected oral communication - Macarena Toll-Riera (Universitat Pompeu Fabra- FIMIM, Spain)
15:05 - 16:15 Poster session 1 (odd numbers) - with coffee/tea
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Medal Lectures
Chair:
Janet Thornton (EMBL-EBI Wellcome Trust Genome, UK)
Early Career Research Award
Araxi Urrutia (Cardiff University, UK)
Transcriptome evolution: shaping genes, genomes... and proteins
Araxi Urrutia - Early Career Research Award (University of Bath, UK)
Louise Johnson (University of Oxford and Diamond Light Source, UK)
The regulation of protein phosphorylation
Louise Johnson - Medal Lecture (University of Oxford and Diamond Light Source, UK)
18:15 - 19:45 Poster session 2 (even numbers) - with drinks reception
19:45 - 21:00 Conference Dinner
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Protein Sequence, structure and function 2
Chairs:
Richard Goldstein (NIMR, UK)
Bengt Mannervik (Uppsala University, Sweden)
A domain family perspective on the evolution of protein functions
Christine Orengo (University College London, UK)
Evolution of duplicated and non duplicated vertebrate proteins
Selected oral communication - Romain Studer (Swiss Institute of Bioinformatics, Switzerland)
The evolution of protein domain families
Alex Bateman (Wellcome Trust Sanger Institute, Cambridge, UK)
10:25 - 11:00 Coffee/tea break
Why there is more to protein evolution than protein function: splicing, nucleosomes and dual-coding sequence
Laurence Hurst (University of Bath, UK)
Evolution of the SNARE protein family in fungi
Selected oral communication - Carl Nickias Kienle (Max Planck Institute for Biophysical Chemistry, Germany)
Protein evolution - a reconstructive approach
Dan Tawfik (Weizmann Institute of Science, Israel)
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Protein systems
Chairs:
Chris Ponting (MRC, University of Oxford, UK)
Christine Orengo (University College London, UK)
Protein-evolution in bacterial stress response
Michael Stumpf (Imperial College London, UK)
metaTIGER: a metabolic evolution resource and its application to horizontal gene transfer
Selected oral communication - John Whitaker (University of Leeds, UK)
Evolution of spectrin function in cytoskeletal and membrane networks
Selected oral communication - Anthony Baines (University of Kent, UK)
14:35 - 15:00 Coffee/tea break
Evolution in protein interaction networks: duplication, rewiring and coevolution
David Robertson (University of Manchester, UK)
Dissection of polyvalent ligand-receptor interactions
Mike Tyers (University of Edinburgh, UK)
Michael Sternberg (Imperial College London, UK)
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