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Molecular biology of Archaea II

16—18 August 2010

Robinson College, Cambridge, UK



Organizers:
Stephen Bell (University of Oxford, UK)
Finn Werner (University College London, UK)

Session 1 DNA metabolism

 

Chair:
Finn Werner (University College London, UK)
Monday 16 August 2010
12:00 - 14:00 Registration and lunch

14:00 - 14:30
Archaeal Nucleotide Excision Repair: finally getting more incisive
Malcolm White (University of St Andrews, UK)
14:30 - 15:00
DNA replication in Thermococcus kodakaraensis
Zvi Kelman (University of Maryland, USA)
15:00 - 15:15
A novel archaeal model for minichromosome maintenance genes in eukaryotes
Selected oral communication - James Chong (University of York, UK)
15:15 - 15:30
The architectural role of Cren7 in crenarchaeal chromatin organization
Selected oral communication - Remus T Dame (Leiden University, The Netherlands)
15:30 - 16:00
Nucleoid Compaction is Part of the Mre11-Rad50-mediated DNA Damage Response in Haloferax volcanii
Thorsten Allers (University of Nottingham, UK)
16:00 - 16:30 Coffee/tea break

Session 2 Molecular anatomy of transcription

 

Chair:
Stephen Bell (University of Oxford, UK)
Monday 16 August 2010
16:30 - 17:00
Molecular anatomy of transcription in the Archaea - structure, function and dynamics of RNA polymerase
Finn Werner (University College London, UK)
17:00 - 17:30
Role of the protruding stalk of the archaeal RNA polymerase in crystal packing and biophysical analysis of the Rpo13 subunit
Nicola Abrescia (CIC BioGUNE, Spain)
17:30 - 17:45
Localization of basal factor TFE in the preinitiation complex
Selected oral communication - Dina Grohmann (University College London, UK)
17:45 - 18:15
Robotic dissection of the catalytic center of archaeal RNA polymerases
Robert Weinzierl (Imperial College London, UK)
18:15 - 20:00 Drinks reception and poster session 1

20:00 - 21:30 Dinner

Session 3 The virus/host arms race

 

Chair:
Christa Schleper (University of Vienna, Austria)
Tuesday 17 August 2010
09:00 - 09:30
Co-evolution of viruses, plasmids and their hosts in Archaea
Patrick Forterre (Institut Pasteur, France)
09:30 - 10:00
Prokaryotic antiviral defence mediated by CRISPR RNA
John van der Oost (University of Wageningen, The Netherlands)
10:00 - 10:15
Replication of the hyperthermophilic archaeal virus AFV1
Selected oral communication - Mery Pina (Institut Pasteur, France)
10:15 - 10:45
Crenarchaeal CRISPR immune systems
Shiraz Shah (University of Copenhagen, Denmark)
10:45 - 11:15 Coffee/tea break

Session 4 Responses to DNA damage

 

Chair:
Thorsten Allers (University of Nottingham, UK)
Tuesday 17 August 2010
11:15 - 11:45
Genome caretakers: a novel Holliday junction resolution activity by reverse gyrase
Maria Ciaramella (CNR, Italy)
11:45 - 12:15
The HerA bipolar helicase from hyperthermophilic archaea
Christiane Elie - CANCELLED (University of Paris Sud, France)
11:45 - 12:00
PELDOR on DNA bending and conformational states of helicases PcrA and Hel308
Selected oral communication - Olav Schiemann (University of St Andrews, UK)
12:00 - 12:15
Mapping physical interaction of Hel308 with RPA: evidence for a loading role that might control homologous recombination
Selected oral communication - Edward Bolt (University of Nottingham, UK)
12:15 - 12:30
Structure and function of a novel endonuclease acting on branched DNA substrates
Selected oral communication - Hannu Myllykallio (INSERM, France)
12:30 - 14:00 Lunch

Session 5 Structures at the cell membrane

 

Chair:
Bettina Siebers (University of Essen, Germany)
Tuesday 17 August 2010
14:00 - 14:30
Assembly of the archaeal flagellum
Sonja Albers (Max Planck Institute for Terrestrial Microbiology, Germany)
14:30 - 15:00
The Sulfolobus information processing and cell division machinerie
Stephen Bell (University of Oxford, UK)
15:00 - 15:15
Ignicoccus hospitalis: 3D architecture, subcellular distribution of the ATP synthase, and spatial separation of metabolic processes
Selected oral communication - Reinhard Rachel (University of Regensburg, Germany)
15:15 - 16:00 Coffee/tea break

Session 6 Global approaches to physiology

 

Chair:
Sonja Albers (Max Planck Institute for Terrestrial Microbiology, Germany)
Tuesday 17 August 2010
16:00 - 16:30
Challenges of life at high temperature
Bettina Siebers (University of Essen, Germany)
16:30 - 17:00
Genomics of the novel phylum Thaumarchaeota
Christa Schleper (University of Vienna, Austria)
17:00 - 17:15
Metaproteomics of a cold-methane seep sediment at Nyegga, Mid-Norwegian margin
Selected oral communication - Runar Stokke (University of Bergen, Norway)
17:15 - 17:30
Ploidy in prokaryotes
Selected oral communication - Jorg Soppa (Goethe-University, Germany)
17:30 - 17:45
Thermophilic archaeal enzymes and their applications in biocatalysis
Selected oral communication - Jennifer Littlechild (University of Exeter, UK)
17:45 - 20:00 Drinks reception and poster session 2

20:00 - 22:00 Conference Dinner

Session 7 From transcript to folded protein

 

Chair:
Patrick Forterre (Institut Pasteur, France)
Wednesday 18 August 2010
09:00 - 09:15
Regulatory RNAs in Haloferax volcanii
Selected oral communication - Anita Marchfelder (Ulm University, Germany)
09:15 - 09:30
Temporal gene regulation of Sulfolobus islandicus rudivirus 2 and the S. solfataricus host cells during virus infection cycle
Selected oral communication - Xu Peng (University of Copenhagen, Denmark)
09:30 - 10:00
Translation initiation in archaea: what's new
Paola Londei (Sapienza University of Rome, Italy)
10:00 - 10:30
Archaeal insights into chaperone-mediated protein folding
Peter Lund (University of Birmingham, UK)
10:30 - 11:00 Coffee/tea break

Session 8 Genetics and mobile genetic elements

 

Chair:
Malcolm White (University of St Andrews, UK)
Wednesday 18 August 2010
11:00 - 11:30
Genetic analysis of the promoter of the arabinose-binding protein gene in Sulfolobus islandicus
Qunxin She (University of Copenhagen, Denmark)
11:30 - 11:45
Investigating the archaeal chromosomal DNA apparatus using a tryptophan-repressible promoter system
Selected oral communication - Agnieszka Swiatek (University of St Andrews, UK)
11:45 - 12:00
Characterization of a homing endonuclease in the halophilic archaeon Haloferax volcanii
Selected oral communication - Uri Gophna (Tel Aviv University, Israel)
12:00 - 12:30
Structure of the primase minimal domain of the pRN1 replication protein
Georg Lipps (University of Applied Sciences of Northwestern Switzerland, Switzerland)
12:30 - 13:00
STIV-Sulfolobus interactions and their relationship to eukaryotic ESCRT proteins
Mark Young (Montana State University, USA)
13:00 - 14:30 Lunch