Special Events
Thudichum Medal Lecture (awarded by the Neuroscience Group)
Glutamate: A molecule to remember
Jeffrey Watkins (Bristol)
Wellcome Trust Award Lecture
The year 2000 integrin model: unleaded fuel, single propeller, traction control, and 0-125 in the shake of a cam¿s tail
Martin Humphries (Manchester)
Timetable
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Biotechnology of Extracellular Matrix
Protein and Peptide Science Group/Techniques Group Colloquium
Organizers:
Karl Kadler (Manchester)
08:30 - 09:00 Neuroscience Group AGM
Overview of biomaterials used in tissue engineering
David Williams (Liverpool)
Wound healing and tissue repair
Potential use of autologous marrow stromal cells for replacement or repair of human skeletal tissues
Darwin Prockop (Philadelphia, USA)
11:00 - 11:30 Coffee Break
Thudichum Medal Lecture (awarded by the Neuroscience Group)
Glutamate: A molecule to remember
Jeffrey Watkins (Bristol)
12:30 - 14:00 Lunch Break
Morphogenesis and tissue engineering: message is in the extracellular matrix
Hari Reddi (California, USA)
Design and expression of novel collagens
Neil Bulleid (Manchester)
Recombinant collagen production in tobacco plants
Florence Ruggiero (Lyon, France)
16:30 - 18:30 Poster Session and tea break
Expression of recombinant human collagens in the yeast Pichia pastoris
Johanna Myllyharju (Oulu, Finland)
Towards a fibrous composite with dynamically controlled stiffness: how do urchins do it
John Trotter (Albuquerque)
Extracellular matrices and matrix/growth factor combinations for bone and cartilage repair: from biology to biotechnology
Rob Spiro (Mountain View, California)
11:00 - 11:30 Coffee Break
Wellcome Trust Award Lecture
The year 2000 integrin model: unleaded fuel, single propeller, traction control, and 0-125 in the shake of a cam¿s tail
Martin Humphries (Manchester)
12:30 - 14:00 Lunch Break and Techniques Group AGM
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Efflux Proteins
Membrane Group/Bioenergetics Group Colloquium
Organizers:
Peter Henderson (Leeds)
Sponsors:
SmithKline Beecham
Microcide Pharmaceuticals Inc
British Biotech Pharmaceuticals Ltd
Bioinformatics and efflux proteins
Ian Paulsen (San Diego, USA)
Expression, purification and properties of antibiotic efflux proteins
10:20 - 11:50 Coffee Break and Poster Session
Structures and regulation of multidrug resistance proteins
Alex Neyfakh (Chicago, USA)
3-Dimensional structure of the sodium efflux protein
Christine Ziegler (Max Planck Institute)
13:10 - 14:30 Lunch Break and Bioenergetics Group AGM
Structures of arsenate/arsenite efflux proteins
Barry Rosen (Detroit, USA)
Structures of related bacterial and mammalian multidrug resistance proteins
Christopher Higgins (Imperial College School of Medicine, London)
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From Protein Folding to New Enzymes
Annual Symposium/British Biophysical Society/Molecular Enzymology Group Colloquium
Organizers:
Alan Berry (Leeds)
Sponsors:
British Biophysical Society
University of Leeds Foundation
08:30 - 09:00 Neuroscience Group AGM
The role of protein topology in protein folding
Luis Serrano (Heidelberg)
Action between the sheets: the acquisition of  -structure in a protein folding reaction
Manipulating the folding of membrane proteins: using the lipid bilayer to our advantage
11:00 - 11:30 Coffee Break
Thudichum Medal Lecture (awarded by the Neuroscience Group)
Glutamate: A molecule to remember
Jeffrey Watkins (Bristol)
12:30 - 14:00 Lunch Break
Protein folding, misfolding and disease
Amyloidosis, protein folding and SAP
Self-perpetuating changes in sup35 protein conformation as a mechanism of heredity in yeast
Understanding and developing therapeutic strategies for human amyloid diseases
Jeff Kelly (Scripps Institute, La Jolla, USA)
16:30 - 18:30 Poster Session and tea break
Structure and assembly of amyloid fibrils
Chaperone assisted protein folding in vitro and in vivo
Ullrich Hartl (Martinsreid, Germany)
Brititsh Biophysical Society sponsored speaker
Interdomain communication in Hsp70 chaperones
Lila Gierasch (Massachusetts)
11:00 - 11:30 Coffee Break
Wellcome Trust Award Lecture
The year 2000 integrin model: unleaded fuel, single propeller, traction control, and 0-125 in the shake of a cam¿s tail
Martin Humphries (Manchester)
12:30 - 14:00 Lunch Break and Techniques Group AGM
Towards a description of protein folding/unfolding at atomic resolution
Valerie Daggett (Seattle, USA)
Protein folding: insights from simulations
Structure, stability and folding of the  -helix
Andrew Doig (UMIST, Manchester)
16:00 - 18:00 Poster Session and tea break
De novo design of helical bundles and protein fibres
The evolution of enzyme structure and function
Evolving new functions for enzymes and enzyme inhibitors
10:20 - 11:50 Coffee Break and Poster Session
New uses for an old enzyme: engineering enzymes for the degradation of explosives
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Moving Signals and Molecules through Membranes
Plant Molecular Biology Colloquium
Organizer:
Philip Gilmartin (Leeds)
08:30 - 09:00 Neuroscience Group AGM
Maria Harrison (Nobel Foundation, USA)
11:00 - 11:30 Coffee Break
Thudichum Medal Lecture (awarded by the Neuroscience Group)
Glutamate: A molecule to remember
Jeffrey Watkins (Bristol)
12:30 - 14:00 Lunch Break
Martin McAinsh (Lancaster)
Ranjan Swarup (Nottingham)
16:30 - 18:30 Poster Session and tea break
11:00 - 11:30 Coffee Break
Wellcome Trust Award Lecture
The year 2000 integrin model: unleaded fuel, single propeller, traction control, and 0-125 in the shake of a cam¿s tail
Martin Humphries (Manchester)
12:30 - 14:00 Lunch Break and Techniques Group AGM
Kostos Tokatlidis (Manchester)
16:00 - 18:00 Poster Session and tea break
Alexandra Andreeva (Oxford Brookes)
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Neuropeptides: from Gene Regulation to Protein Processing
Neuroscience Group Colloquium
Organizer:
Tony Turner (Leeds)
08:30 - 09:00 Neuroscience Group AGM
Turning off neuropeptide signals: proteolysis and receptor trafficking
Nigel Bunnett (San Francisco, USA)
XCE, a novel CNS processing enzyme controlling respiration: transgenic and other studies
Olivier Valdenaire (Paris, France)
Neuropeptidases regulating gonadal function
A. Ian Smith (Melbourne, Australia)
11:00 - 11:30 Coffee Break
Thudichum Medal Lecture (awarded by the Neuroscience Group)
Glutamate: A molecule to remember
Jeffrey Watkins (Bristol)
12:30 - 14:00 Lunch Break
Aminopeptidase A and a novel brain angiotensin system mediating systemic cardiovascular control
Catherine Llorens-Cortes (Paris, France)
Protein processing mechanisms: from ACE to Alzheimer's
The complexity of transcriptional control in neuropeptide gene expression
Denes von Agoston (Bethesda, USA)
Neuroprotective peptides of the VIP family
Douglas Brenneman (Bethesda, USA)
16:30 - 18:30 Poster Session and tea break
Applications of combinatorial chemistry to the study of neuropeptide and peptidase function
Vincent Dive (CEA - Saclay)
Conserved roles for peptidases in the processing of invertebrate neuropeptides
Exploring the C. elegans and Drosophila genomes to understand neuropeptide and peptidase function
11:00 - 11:30 Coffee Break
Wellcome Trust Award Lecture
The year 2000 integrin model: unleaded fuel, single propeller, traction control, and 0-125 in the shake of a cam¿s tail
Martin Humphries (Manchester)
12:30 - 14:00 Lunch Break and Techniques Group AGM
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Steroid Receptor Coactivators and the Remodelling of Chromatin
Hormone Group Colloquium
Organizer:
Iain McEwan (Aberdeen)
Sponsor:
Cambridge Bioscience
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Chromatin Structure and Remodelling
Nucleosome asymmetry and chromatin organization
Andrew Travers (Cambridge)
Mechanisms for ATP-dependent chromatin remodelling
The Elongator complex: coupling chromatin modification to transcriptional elongation
11:00 - 11:30 Coffee Break
Wellcome Trust Award Lecture
The year 2000 integrin model: unleaded fuel, single propeller, traction control, and 0-125 in the shake of a cam¿s tail
Martin Humphries (Manchester)
12:30 - 14:00 Lunch Break and Techniques Group AGM
Acetylation as a multi-functional modification
Tony Kouzarides (Cambridge)
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Role of Co-activators and Co-repressors in Nuclear Receptor Function
12:30 - 14:00 Lunch Break and Techniques Group AGM
Co-repressor complexes and remodelling chromatin for repression
Fyodor Urnov (Bethesda, USA)
Mediation and modulation of thyroid hormone receptor repression
Rainer Renkawitz (Germany)
16:00 - 18:00 Poster Session and tea break
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Steroid Receptors/Co-activators and Chromatin
Nuclear receptor:co-repressor interactions
John Schwabe (MRC, Cambridge)
Relating structure to function in the oestrogen receptor(s)
Androgen receptor-interacting nuclear proteins
10:20 - 11:50 Coffee Break and Poster Session
Dynamics of gene targeting and chromatin remodelling by nuclear receptors
Gordon Hager (Bethesda, USA)
Mechanisms of chromatin remodelling by the glucocorticoid receptor
Anthony Wright (Huddinge)
Protein methyltransferases as coactivators for steroid receptors
Michael Stallcup (Southern California)
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Teaching Bioinformatics
Education Group Colloquium
Organizer:
Clare Sansom (London)
Why teach bioinformatics?
James Milner-White (Glasgow)
Bioinformatics in the undergraduate curriculum
10:20 - 11:50 Coffee Break and Poster Session
Do tomorrow's doctors need to know bioinformatics?
Steve Perkins (Royal Free Hospital, London)
Preparing graduates for the pharmaceutical industry
Charlie Hodgman (Glaxo Wellcome, Stevenage)
13:10 - 14:30 Lunch Break and Bioenergetics Group AGM
Bioinformatics at MSc level: different approaches
Biocomputing teaching and the internet
Georg Fuellen (Bielefeld)
The HGMP resource centre, EMBnet and training
Jon Ison (MRC, Cambridge)
Interactive websites as bioinformatics teaching aids
Jo McEntyre (NCBI, NIH, USA)
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