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Biochemical Society Meeting 677

16—18 July 2002

Cardiff University, UK



Special Events

Wednesday 17 July 2002
11:30 - 12:30
Colworth Medal Lecture
Tom Owen-Hughes (Dundee, UK)

Timetable

Tuesday 16 July 2002Wednesday 17 July 2002Thursday 18 July 2002
09:00 - 16:00
Structure-Function Studies of the Complement System

09:00 - 16:00
Regulation of Fatty Acid Synthesis

09:00 - 16:00
Plant Food Allergens

13:00 - 18:00
Careers Advice Workshop for Young Researchers

08:45 - 17:40
Host Colloquium: Biology of the Intervertebral Disc

08:45 - 18:00
Plant Food Allergens

08:45 - 17:40
Regulation of Fatty Acid Synthesis

08:45 - 18:00
Structure-Function Studies of the Complement System

08:45 - 16:00
Host Colloquium: Biology of the Intervertebral Disc

08:45 - 16:00
Plant Food Allergens

08:45 - 16:00
Structure-Function Studies of the Complement System

11:40 - 16:40
Biochemists in the Pursuit of Numeracy


Host Colloquium: Biology of the Intervertebral Disc

Related books

Organizer:
Vic Duance (Cardiff, UK)
Wednesday 17 July 2002
08:45 - 09:25
Clinical importance of the intervertebral disc
Jeremy Fairbank (Oxford, UK)
09:25 - 10:05
Development of the annulus fibrosus
Jim Ralphs (Cardiff, UK)
10:05 - 10:45
Collagen gene expression in intervertebral disc development
Linda Sandell (St Louis, MO, USA)
10:45 - 11:30 Coffee Break

11:30 - 12:30
Colworth Medal Lecture
Tom Owen-Hughes (Dundee, UK)
12:30 - 13:30 Lunch Break

13:30 - 14:10
The role of disc cell heterogeneity in determining disc biochemistry: a speculation
Theodore Oegema (Minnesota, USA)
14:10 - 14:50
Aggrecan and small interstitial proteoglycan metabolism in aged and pathological disc tissue
Bruce Caterson (Cardiff, UK)
14:50 - 16:20 Coffee Break and Poster Viewing

16:20 - 17:00
Collagen polymorphisms of the intervertebral disc
David Eyre (Washington, WA, USA)
17:00 - 17:40
Elastic tissues of the intervertebral disc
Jing Yu (Oxford, UK)
Thursday 18 July 2002
08:45 - 09:25
Mechanobiology of the intervertebral disc
Jeff Lotz (California, CA, USA)
09:25 - 10:05
The role of the physicochemical environment in determining disc cell behaviour
Jill Urban (Oxford, UK)
10:05 - 11:40 Coffee Break and Poster Viewing

11:40 - 12:20
Disc morphology in health and disease
Sally Roberts (Spinal Research Centre, Oswestry, UK)
12:20 - 13:00
The role of proteoglycans in aging, degeneration and repair of the intervertebral disc
Peter Roughley (Shriners Hospital, Montreal, Canada)
13:00 - 14:00 Lunch Break

14:00 - 14:40
Compartmentalization of the matrix formed by nucleus pulposus and annulus fibrosus cells in alginate gel
Eugene Thonar (Rush Medical College, Chicago, USA)
14:40 - 15:20
Engineering cartilaginous tissues
Tim Hardingham (Manchester, UK)
15:20 - 16:00
Future perspectives for treatment of back pain
Stephen Eisenstein (Spinal Research Centre, Oswestry, UK)

Structure-Function Studies of the Complement System

Related books

Organizers:
Paul Morgan (Cardiff, UK)
Parvez Haris (De Montfort, UK)
Sponsor:
Thursday 18 July 2002
08:45 - 09:25
Solution structure of allergenic 2S Albumins
Manuel Rico (Madrid, Spain)
09:25 - 10:05
Structural attributes of the cupins and their role in determining the allergenic activity of plant seed storage globulins
Clare Mills (Institute of Food Research, Norwich, UK)
10:05 - 11:40 Coffee Break and Poster Viewing

11:40 - 12:20
PR-proteins identified as allergens
Karin Hoffman-Sommergruber (Vienna, Austria)
12:20 - 13:00
The latex-fruit syndrome
Stefan Wagner ( Vienna, Austria)
13:00 - 14:00 Lunch Break

14:00 - 14:40
Industrial dimensions of food allergy
Rene Crevel ( Unilever Research, Bedford, UK)
14:40 - 15:20
Plant biotechnology and plant food allergens
Larry Beach (Pioneer HiBred International, Johnston, IA, USA)
15:20 - 16:00
Lactic acid bacteria for mucosal vaccines and therapy
Sean Hanniffy (Institute of Food Research, Norwich, UK)

Structure-function in RCA proteins

Tuesday 16 July 2002
09:00 - 09:15
Thymosin 4 is mechanically regulated in articular cartilage
Emma Blain (Cardiff, UK)
09:00 - 09:40
Structural studies of Factor H family proteins: on complement, microbes and human diseases
Peter Zipfel (Hans Knoell Institute for Natural Product Research, Beutenbergstrasse, Germany)
09:15 - 09:30
Degradation of articular cartilage superficial zone proteoglycan (SZP) by matrix proteases
Aled Jones (Cardiff, UK)
09:30 - 09:45
Erythropoietin modulates interleukin-1 induced nitrite production in rheumatoid synovial fibroblasts
Somara Baig (Luton, UK)
09:40 - 10:20
Structural studies in C4b-binding protein
Anna Blom (Malmo, Sweden)
09:45 - 10:00
PACT, the protein activator of PKR is up-regulated at the onset of osteoarthritis and by TNF- treatment of chondrocytes
Sophie Gilbert
10:00 - 10:15
The role of glutamate transporters in bone remodelling
Jim Huggett (Cardiff, UK)
10:15 - 11:00 Coffee Break

10:20 - 11:00 Coffee Break

11:00 - 11:40
Recent developments in cartilage research
David Eyre (Washington, WA, USA)
11:00 - 11:40
Structure of CR2 and CR2/C3dg complexes
Michael Holers (Denver, CO, USA)
11:40 - 11:55
Antioxidants decrease cell death in experimentally wounded articular cartilage
Ilyas Khan (Cardiff, UK)
11:40 - 12:20
Three-dimensional structure and flexibility of proteins of the RCA family
Paul Barlow (Edinburgh, UK)
11:55 - 12:10
mRNA gene expression patterns in osteochondrosis dessicans
Clare Curtis (Cardiff, UK)
12:10 - 12:25
Cysteine Mutations of Fibrillin-1 in Marfan Syndrome
Ji-Young Suk (Oxford, UK)
12:20 - 14:00 Lunch and Poster Viewing

12:25 - 14:00 Lunch and Poster Viewing

Structure-function in the activation pathways

Tuesday 16 July 2002
09:00 - 09:15
Thymosin 4 is mechanically regulated in articular cartilage
Emma Blain (Cardiff, UK)
09:15 - 09:30
Degradation of articular cartilage superficial zone proteoglycan (SZP) by matrix proteases
Aled Jones (Cardiff, UK)
09:30 - 09:45
Erythropoietin modulates interleukin-1 induced nitrite production in rheumatoid synovial fibroblasts
Somara Baig (Luton, UK)
09:45 - 10:00
PACT, the protein activator of PKR is up-regulated at the onset of osteoarthritis and by TNF- treatment of chondrocytes
Sophie Gilbert
10:00 - 10:15
The role of glutamate transporters in bone remodelling
Jim Huggett (Cardiff, UK)
10:15 - 11:00 Coffee Break

11:00 - 11:40
Recent developments in cartilage research
David Eyre (Washington, WA, USA)
11:40 - 11:55
Antioxidants decrease cell death in experimentally wounded articular cartilage
Ilyas Khan (Cardiff, UK)
11:55 - 12:10
mRNA gene expression patterns in osteochondrosis dessicans
Clare Curtis (Cardiff, UK)
12:10 - 12:25
Cysteine Mutations of Fibrillin-1 in Marfan Syndrome
Ji-Young Suk (Oxford, UK)
12:25 - 14:00 Lunch and Poster Viewing

14:00 - 14:40
Solution structures of complement components by scattering and ultracentrifugation
Stephen Perkins (London, UK)
14:40 - 15:20
Structural biology of C1
Gerard Arlaud (Institute de Biologie Structurale Jean-Pierre Ebel, Grenoble, France)
15:20 - 16:00
Structure-function studies of the C5 convertase
Michael Pangburn (Texas, TX, USA)

Interaction of C regulators and receptors with non-C ligands

Tuesday 16 July 2002
09:00 - 09:15
Thymosin 4 is mechanically regulated in articular cartilage
Emma Blain (Cardiff, UK)
09:15 - 09:30
Degradation of articular cartilage superficial zone proteoglycan (SZP) by matrix proteases
Aled Jones (Cardiff, UK)
09:30 - 09:45
Erythropoietin modulates interleukin-1 induced nitrite production in rheumatoid synovial fibroblasts
Somara Baig (Luton, UK)
09:45 - 10:00
PACT, the protein activator of PKR is up-regulated at the onset of osteoarthritis and by TNF- treatment of chondrocytes
Sophie Gilbert
10:00 - 10:15
The role of glutamate transporters in bone remodelling
Jim Huggett (Cardiff, UK)
10:15 - 11:00 Coffee Break

11:00 - 11:40
Recent developments in cartilage research
David Eyre (Washington, WA, USA)
11:40 - 11:55
Antioxidants decrease cell death in experimentally wounded articular cartilage
Ilyas Khan (Cardiff, UK)
11:55 - 12:10
mRNA gene expression patterns in osteochondrosis dessicans
Clare Curtis (Cardiff, UK)
12:10 - 12:25
Cysteine Mutations of Fibrillin-1 in Marfan Syndrome
Ji-Young Suk (Oxford, UK)
12:25 - 14:00 Lunch and Poster Viewing

16:00 - 18:00 Poster Session and Drinks Reception

Wednesday 17 July 2002
08:45 - 09:25
Structure-function studies of the receptors for complement C1q
Philippe Gasque (Cardiff, UK)
09:25 - 10:05
CR1: evolving to the tune of a powerful pathogen
John Atkinson (St Louis, MO, USA)
09:25 - 10:05
Clinical aspects of food allergy
Photini Papageorgiou (Athens, Greece)
10:05 - 10:45
Structure function of CD46 (membrane cofactor protein) and interactions with measles virus
Denis Gerlier (Lyon, France)
10:05 - 10:45
Epidemiology of food allergy : children of the 90s project
Jean Golding and Kate Northstone (Institute of Child Health, Bristol, UK)
10:45 - 11:30 Coffee Break

10:45 - 11:30 Coffee Break

11:30 - 12:30
Colworth Medal Lecture
Tom Owen-Hughes (Dundee, UK)
12:30 - 13:30 Lunch Break

12:30 - 13:30 Lunch Break

13:30 - 14:10
Plant protein families
Peter Shewry (IACR-Long Ashton Research Station, Bristol, UK)
13:30 - 14:10
Interactions of CD55 with non-C ligands
Susan Lea (Oxford, UK)
14:10 - 14:50
Structural aspects of ns LTPs
Didier Marion (INRA-Nantes, France)
14:50 - 16:20 Coffee Break and Poster Viewing

16:20 - 17:00
Clinical importance of ns LTPs
Ronald van Ree (Amsterdam, Netherlands)
17:00 - 17:20
Stability of 2S albumin allergens in vitro
Selected poster presentation - Gareth Murtagh (Nottingham, UK)
17:40 - 18:00
The stability of diet-derived proteins to pepsin digestion and potential allergenicity
Selected poster presentation - Gary Burnett (Institute of Food Research, Norwich, UK)

Rational design of anticomplement therapeutics

Wednesday 17 July 2002
09:25 - 10:05
Clinical aspects of food allergy
Photini Papageorgiou (Athens, Greece)
10:05 - 10:45
Epidemiology of food allergy : children of the 90s project
Jean Golding and Kate Northstone (Institute of Child Health, Bristol, UK)
10:45 - 11:30 Coffee Break

11:30 - 12:30
Colworth Medal Lecture
Tom Owen-Hughes (Dundee, UK)
12:30 - 13:30 Lunch Break

13:30 - 14:10
Plant protein families
Peter Shewry (IACR-Long Ashton Research Station, Bristol, UK)
14:10 - 14:50
Structural aspects of ns LTPs
Didier Marion (INRA-Nantes, France)
14:10 - 14:50
Tailoring anticomplement therapeutics
Paul Morgan (University of Wales College of Medicine, UK)
14:50 - 16:20 Coffee Break and Poster Viewing

14:50 - 16:20 Coffee Break and Poster Viewing

16:20 - 17:00
Rational design of a complement inhibitor targeting C3 using NMR and combinatorial approaches
John Lambris (Philadelphia, PA, USA)
16:20 - 17:00
Clinical importance of ns LTPs
Ronald van Ree (Amsterdam, Netherlands)
17:00 - 17:40
Targeting anticomplement agents
Richard Smith (Adprotech plc, Essex, UK)
17:00 - 17:20
Stability of 2S albumin allergens in vitro
Selected poster presentation - Gareth Murtagh (Nottingham, UK)
17:40 - 18:00
The stability of diet-derived proteins to pepsin digestion and potential allergenicity
Selected poster presentation - Gary Burnett (Institute of Food Research, Norwich, UK)

Plant Food Allergens

Industrial Biochemistry and Biotechnology Group

Related books

Organizers:
Clare Mills (IFR, Norwich, UK)
Paul Davis (Unilever, UK)
Peter Shewry (IACR-Long Ashton, Bristol, UK)
Tuesday 16 July 2002
09:00 - 09:15
Thymosin 4 is mechanically regulated in articular cartilage
Emma Blain (Cardiff, UK)
09:00 - 09:40
Structural studies of Factor H family proteins: on complement, microbes and human diseases
Peter Zipfel (Hans Knoell Institute for Natural Product Research, Beutenbergstrasse, Germany)
09:15 - 09:30
Degradation of articular cartilage superficial zone proteoglycan (SZP) by matrix proteases
Aled Jones (Cardiff, UK)
09:30 - 09:45
Erythropoietin modulates interleukin-1 induced nitrite production in rheumatoid synovial fibroblasts
Somara Baig (Luton, UK)
09:40 - 10:20
Structural studies in C4b-binding protein
Anna Blom (Malmo, Sweden)
09:45 - 10:00
PACT, the protein activator of PKR is up-regulated at the onset of osteoarthritis and by TNF- treatment of chondrocytes
Sophie Gilbert
10:00 - 10:15
The role of glutamate transporters in bone remodelling
Jim Huggett (Cardiff, UK)
10:15 - 11:00 Coffee Break

10:20 - 11:00 Coffee Break

11:00 - 11:40
Recent developments in cartilage research
David Eyre (Washington, WA, USA)
11:00 - 11:40
Structure of CR2 and CR2/C3dg complexes
Michael Holers (Denver, CO, USA)
11:40 - 11:55
Antioxidants decrease cell death in experimentally wounded articular cartilage
Ilyas Khan (Cardiff, UK)
11:40 - 12:20
Three-dimensional structure and flexibility of proteins of the RCA family
Paul Barlow (Edinburgh, UK)
11:55 - 12:10
mRNA gene expression patterns in osteochondrosis dessicans
Clare Curtis (Cardiff, UK)
12:10 - 12:25
Cysteine Mutations of Fibrillin-1 in Marfan Syndrome
Ji-Young Suk (Oxford, UK)
12:20 - 14:00 Lunch and Poster Viewing

12:25 - 14:00 Lunch and Poster Viewing

14:00 - 14:40
Solution structures of complement components by scattering and ultracentrifugation
Stephen Perkins (London, UK)
14:40 - 15:20
Structural biology of C1
Gerard Arlaud (Institute de Biologie Structurale Jean-Pierre Ebel, Grenoble, France)
15:20 - 16:00
Structure-function studies of the C5 convertase
Michael Pangburn (Texas, TX, USA)
16:00 - 18:00 Poster Session and Drinks Reception

Clinical Context of Plant Food Allergies

Wednesday 17 July 2002
08:45 - 09:25
Structure-function studies of the receptors for complement C1q
Philippe Gasque (Cardiff, UK)
09:25 - 10:05
CR1: evolving to the tune of a powerful pathogen
John Atkinson (St Louis, MO, USA)
09:25 - 10:05
Clinical aspects of food allergy
Photini Papageorgiou (Athens, Greece)
10:05 - 10:45
Structure function of CD46 (membrane cofactor protein) and interactions with measles virus
Denis Gerlier (Lyon, France)
10:05 - 10:45
Epidemiology of food allergy : children of the 90s project
Jean Golding and Kate Northstone (Institute of Child Health, Bristol, UK)
10:45 - 11:30 Coffee Break

10:45 - 11:30 Coffee Break

11:30 - 12:30
Colworth Medal Lecture
Tom Owen-Hughes (Dundee, UK)
12:30 - 13:30 Lunch Break

12:30 - 13:30 Lunch Break

13:30 - 14:10
Interactions of CD55 with non-C ligands
Susan Lea (Oxford, UK)

Plant Food Allergen Protein Families

Wednesday 17 July 2002
08:45 - 09:25
Structure-function studies of the receptors for complement C1q
Philippe Gasque (Cardiff, UK)
09:25 - 10:05
CR1: evolving to the tune of a powerful pathogen
John Atkinson (St Louis, MO, USA)
10:05 - 10:45
Structure function of CD46 (membrane cofactor protein) and interactions with measles virus
Denis Gerlier (Lyon, France)
10:45 - 11:30 Coffee Break

11:30 - 12:30
Colworth Medal Lecture
Tom Owen-Hughes (Dundee, UK)
12:30 - 13:30 Lunch Break

13:30 - 14:10
Plant protein families
Peter Shewry (IACR-Long Ashton Research Station, Bristol, UK)
13:30 - 14:10
Interactions of CD55 with non-C ligands
Susan Lea (Oxford, UK)
14:10 - 14:50
Structural aspects of ns LTPs
Didier Marion (INRA-Nantes, France)
14:50 - 16:20 Coffee Break and Poster Viewing

16:20 - 17:00
Clinical importance of ns LTPs
Ronald van Ree (Amsterdam, Netherlands)
17:00 - 17:20
Stability of 2S albumin allergens in vitro
Selected poster presentation - Gareth Murtagh (Nottingham, UK)
17:40 - 18:00
The stability of diet-derived proteins to pepsin digestion and potential allergenicity
Selected poster presentation - Gary Burnett (Institute of Food Research, Norwich, UK)
Thursday 18 July 2002
08:45 - 09:25
Solution structure of allergenic 2S Albumins
Manuel Rico (Madrid, Spain)
09:25 - 10:05
Structural attributes of the cupins and their role in determining the allergenic activity of plant seed storage globulins
Clare Mills (Institute of Food Research, Norwich, UK)
10:05 - 11:40 Coffee Break and Poster Viewing

11:40 - 12:20
PR-proteins identified as allergens
Karin Hoffman-Sommergruber (Vienna, Austria)
12:20 - 13:00
The latex-fruit syndrome
Stefan Wagner ( Vienna, Austria)
13:00 - 14:00 Lunch Break

Industrial Dimensions of Food Allergy

Thursday 18 July 2002
14:00 - 14:40
Industrial dimensions of food allergy
Rene Crevel ( Unilever Research, Bedford, UK)
14:40 - 15:20
Plant biotechnology and plant food allergens
Larry Beach (Pioneer HiBred International, Johnston, IA, USA)
15:20 - 16:00
Lactic acid bacteria for mucosal vaccines and therapy
Sean Hanniffy (Institute of Food Research, Norwich, UK)

Regulation of Fatty Acid Synthesis

Regulation of Metabolism Group and Lipid Group

Related books

Organizers:
John Harwood (Cardiff, UK)
Matthew Hills (John Innes Centre, Norwich, UK)
Tuesday 16 July 2002
09:00 - 09:40
Carbon flow for fatty acid synthesis
Steve Rawsthorne (John Innes Centre, Norwich, UK)
09:40 - 10:20
Regulation of lipid accumulation in oleaginous microorganisms
Colin Ratledge (Hull, UK)
10:20 - 11:00 Coffee Break

11:00 - 11:40
Mechanistic diversity and regulation of type II fatty acid synthesis
Charles Rock (Memphis, TN, USA)
11:40 - 12:20
Regulation of fatty acid biosynthesis
Antoni Slabas (Durham, UK)
12:20 - 14:00 Lunch and Poster Viewing

14:00 - 14:40
Regulation of mammalian acetyl-CoA carboxylase
Michael Munday (London, UK)
14:40 - 15:20
Regulation of fatty acid synthesis and degradation by the AMP-activated protein kinase
Graham Hardie (Dundee, UK)
15:20 - 15:40
Transcription factors acting on the promoter of the fatty acid synthase gene
Selected poster presentation - Michael Schweizer (Heriot-Watt, UK)
15:40 - 16:00
Altering specificity of a Ricinus communis cytochrome b5 fusion desaturase
Selected poster presentation - Louise Michaelson (IACR Long Ashton Research Station, Bristol, UK)
16:00 - 18:00 Poster Session and Drinks Reception

Wednesday 17 July 2002
08:45 - 09:25
Gene regulation of mammalian desaturases
Manabu Nakamura (Urbana, IL, USA)
09:25 - 10:05
Yeast desaturases
Charles Martin (Rutgers, NJ, USA)
10:05 - 10:45
Environmentaly-induced regulation of acyl-CoA desaturase genes
Andrew Cossins (Liverpool, UK)
10:45 - 11:30 Coffee Break

11:30 - 12:30
Colworth Medal Lecture
Tom Owen-Hughes (Dundee, UK)
12:30 - 13:30 Lunch Break

13:30 - 14:10
Peroxisome proliferator activated receptors (PPAR) and the regulation of mammalian fatty acid metabolism
Stephen Smith (GlaxoSmithKline, Harlow, UK)
14:10 - 14:50
The role of sterol regulatory element binding protein in regulating fatty acid synthesis
Jay Horton (Texas, USA)
14:50 - 16:20 Coffee Break and Poster Viewing

16:20 - 17:00
Factors affecting yield of unusual fatty acids in engineered oilseeds
Ian Graham (York, UK)
17:00 - 17:40
Regulation of fatty acid production in transgenic crops
Tony Kinney (Wilmington, DE, USA)

Biochemists in the Pursuit of Numeracy

Education Group

Organizer:
David Harris (Oxford,UK)
Thursday 18 July 2002
10:05 - 11:40 Coffee Break & Poster Session

11:40 - 12:20
Maths - bridging the gaps between the haves and have nots
Elspeth Garman (Oxford, UK)
12:20 - 13:00
A view from across the bridge
John Fink (Kalamazoo, MI, USA)
13:00 - 14:00 Lunch Break

14:00 - 14:40
Core zero curriculum and the life scientist!
David Phoenix (Central Lancashire, UK)
14:40 - 15:20
Practical statistics for the biosciences
Steve Ashcroft (Oxford, UK)
15:20 - 16:00
Converting biochemical results to clinically meaningful decisions
Rick Jones
16:00 - 16:20
Towards long life and happiness: the training of numerate pharmacy students
Jill Barber (Manchester, UK)
16:20 - 16:40
Diluting the drugs with ignorance
Judith Rees (Manchester, UK)
16:40 - 17:20 Discussion

Research Colloquium: Connective Tissue

Related books


Careers Advice Workshop for Young Researchers

More information

Organizers:
Liz Dallimore (The Biochemical Society)
Mike Withnall (The Biochemical Society)
Tuesday 16 July 2002
13:00 - 14:00
Various employers involved in science recruitment will be available to review submitted CV's
CV Clinic
14:00 - 14:30
Careers in teaching and research in academia
Teresa Tetley (Imperial College, London, UK)
14:30 - 15:00
Careers in sales and marketing for industry
David Ley (Hamilton Northern Europe, UK)
15:00 - 15:30
Careers in scientific administration/changing careers
Nigel Titchen (BBSRC and IGER, North Wyke, UK)
15:30 - 16:00
Careers in financial institution
Carolyn Keenan (Ernst & Young, Reading, UK)
16:00 - 16:30
Careers in biological sciences for industry
Lucy Reynolds (BD Biosciences, Oxford, UK)
16:30 - 18:00
A variety of different organizations employing scientists will be presenting stands, along with the Science Recruitment Group who will available to provide recruitment and CV advice.
Exhibition of Careers Stands and Drinks Reception