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The testis as a conduit for genomic plasticity

15—18 November 2006

University of Leeds



Organizers:
Martin Brinkworth (University of Bradford, UK)
Stephen Krawetz (Wayne State University, USA)
Jim Cummins (Murdoch University, Australia)
David Miller (University of Leeds, UK)
Corrado Spadafora (Institutio Superiore di Sanità, Italy)

Introduction

Wednesday 15 November 2006
16:00 - 18:00 Advanced Workshop registration
(Merrion Hotel, Leeds)

Thursday 16 November 2006
08:00 - 08:30 Registration and coffee

08:30 - 09:30
Introduction to the Advanced Workshop
The testis as a conduit for genomic plasticity
David Miller and Martin Brinkworth (University of Leeds/ University of Bradford, UK)

Is the testis a permissive environment for reposition?

Session 1

Thursday 16 November 2006
09:30 - 10:15
Transcriptional promiscuity of the testis
Ed Schmidt (Montana State University, USA)
10:15 - 11:00
Reverse transcription (RNA to DNA) and genomic plasticity
Jurgen Brosius (University of Munster Von-Esmarch-Str, Germany)
11:00 - 11:45
Rethinking genomes and evolution in 21st Century terms
Jim Shapiro (University of Chicago, USA)
11:45 - 12:00 Break

12:00 - 12:45
LINE and SINE elements
John Moran (University of Michigan)
12:45 - 13:30 Lunch
close of session

Session 1


DNA and RNA dynamics of gametes: new portals for lateral gene transfer?

Session 2

Thursday 16 November 2006
13:30 - 14:15
Histone substitution by protamines
Rod Balhorn (Lawrence Livermore National Laboratories, USA)
14:15 - 15:00
Chromatin domains in spermatoza
Andrei Zalensky (Jones Institute, East Virginia Medical School, USA)
15:00 - 15:45
Chromatin architecture in the sperm nucleus
Steve Krawetz (Wayne State University, Detroit, USA)
15:45 - 16:00 Break

16:00 - 16:45
The role of DNA methylation in genomic reprogramming and programming
Lorraine Young (University of Nottingham, UK)
16:45 - 17:30
Molecular dynamics and evolutionary aspects of the oocyte to embryo transition
Barbara Knowles (University of Nottingham, UK)
17:30 - 18:00 Discussion
close of session

18:00 - 19:00 Poster Session 1

20:00 - 23:00 Yorkshire Mummers
followed by dinner

Session 2


Chromatin domains and imprinting phenomena

Advanced Workshop

Friday 17 November 2006
09:00 - 09:45
Loops, auto-digestion and other features of spermatozal DNA
Steve Ward (Univesity of Hawaii, USA)
09:45 - 10:30
Potential of spermatozal RNA for infertility studies
David Dix (Environmental Protection Agency, USA)
10:30 - 11:15
Sperm-mediated
Corrado Spadafora (Istituto Superiore di Sanitá, Italy)
11:15 - 11:30 Break

11:30 - 12:15
New insights into spermatozal chromatin packaging and RNA carriage
Ali Arpanahi and Adam Dawe (University of Leeds, UK)
12:15 - 14:00 Lunch

Session 3


Annual meeting of the BAS.

BAS Session I

Friday 17 November 2006
14:00 - 14:45
Provirus in the male reproductive tract
Ann Keissling (Harvard University, USA)
14:45 - 15:30
RNA dynamics of 'fertile' and 'infertile' spermatoza
Serge Carreau (University of Caen, France)
15:30 - 15:50 Free communication 1

15:50 - 16:15 Break

16:15 Free communictaion 2

16:35 - 16:55 Free communication 3

16:55 - 17:40
Oestrogenic effects on sperm DNA
Diane Andreson (University of Bradford, UK)
17:40 - 18:00 Discussion
close of Session I

18:00 - 19:00 Poster Session 2
and BAS committee meeting

20:00 Dinner and free 70s Disco
(licenced bar available)

Extrinsic and intrinsic effects on sperm function


Annual Meeting of the BAS (continued)

BAS Session II


Epididymal effects on sperm maturation

Saturday 18 November 2006
09:00 - 09:45
Sperm physiology and osmolyte transport
Trevor Cooper (University of Muenster, Germany)
09:45 - 10:05 Free communication 4

10:05 - 10:25 Break

10:25 - 11:00
Organisation and structure of sperm membranes during epidiymal maturation
Roy Jones (Babraham Institute, Cambridge, UK)
12:30
Concluding remarks
David Miller (University of Leeds, UK)

Is semen analysis still a useful excercise?

Saturday 18 November 2006
09:45 - 10:05 Free communication 4

10:05 - 10:25 Break

11:10 - 12:30
discussion on the meritis/semen analysis in the modern assisted contraception setting
Bill Holt (Institute of Zoology, London, UK)
12:30
Concluding remarks
David Miller (University of Leeds, UK)