Organizer:
Susanne Klumpp (University of Muenster, Germany)
|
Students' programme
Review-like introductore talks (45 min, resp.)
Not for students only!
Chairpersons: G. Del Zoppo, A. Planas
Neurovascular aspects in ischemia
Gregory Del Zoppo (La Jolla, USA)
Signal transduction: when cells die
Anna Planas (Barcelona, Spain)
16:30 - 17:00 Coffee break
Developing neuroprotection for the treatment of stroke
Wolf-Rüdiger Schäbitz (Muenster, Germany)
Brain immune system interactions after stroke
Ulrich Dirnagel (Berlin, Germany)
|
Cellular signalling
Chairpersons: J. Hallenbeck, M. Ginsberg
Functional analysis of the protein tyrosine phosphatase superfamily
KEYNOTE LECTURE: Nick Tonks (Cold Spring Harbour, USA)
Endogenous neuroprotective signalling at the cross roads of
Nicolas Bazan (New Orleans, USA)
Mitochondrial translocation of P53 underlies the selective death
Signalling molecules essential for neuronal survival and differentiation
Stefan Wiese (Würzburg, Germany)
10:45 - 11:05 Coffee break
|
Cellular signalling
Chairpersons: N. Bazan, P. Chan
NF-kappaB signalling in cerebral ischemia
Markus Schwaninger (Heidelberg, Germany)
Signalling pathways mediating inflammatory responses in brain ischemia
Anna Planas (Barcelona, Spain)
Downstream effectors of COX-2 neurotoxicity
Costantino Iadecola (New York, USA)
Insights into cytoprotection from ground squirrel hibernation,
John Hallenbeck (Bethesda, USA)
|
Regulation by reversible phosphorylation
Chairpersons: C. Klee, N. Tonks
Control of neuronal excitability by phosphorylation and dephosphorylation
Todd Scheurer (Seattle, USA)
Kinases and calcium signaling in neurodegeneration
Pierluigi Nicotera (Leicester, UK)
Protein kinase B / Akt at a glance
Brian Hemmings (Basel, Switzerland)
15:15 - 15:35 Coffee break
|
Regulation by reversible phosphorylation
Chairpersons: P. Nicotera, L. Pinna
Claude Klee (Bethesda, USA)
Regulation and functions of the lipid and protein phosphatase activities
Peter Downes (Dundee, UK)
Protein kinase CK2: An unforeseen member of the ¿druggable¿ kinome
Lorenzo Pinna (Padova, Italy)
|
Genomics, gene theraphy and clinical trials
Chairpersons: M. Chopp, V. Dawson
Turning on genes to protect the brain
Valina Dawson (Baltimore, USA)
Gene and stem cell therapy for ischemic brain
Koji Abe (Okayama, Japan)
Genomics of stroke in human patients
Alison Baird (Bethesda, USA)
Gene expression in the blood of patients following acute ischemic stroke: major role of PMNs and monocytes
Frank Sharp (Sacramento, USA)
10:10 - 10:30 Coffee break
|
Genomics, gene theraphy and clinical trials
Chairpersons: A. Buchan, F. Sharp
Translational vehicles for neuroprotection
Alastair Buchan (Oxford, UK)
The albumin in acute stroke phase III randomized multicenter clinical trial: design and progress report
Myron Ginsberg (Miami, USA)
12:30 - 15:00 Poster session
|
Neuroprotection
Chairpersons: U. Dirnagl, S. Lipton
A novel ER stress pathway to neuronal damage and protection
Stuart Lipton (La Jolla, USA)
Neuroprotective effects of G-CSF in MCAO model
Chuanzhen Lu (Shanghai, China)
Protective effects of novel small molecule Bid inhibitors in models of neurodegenerative disorders
Carsten Culmsee (Munich, Germany)
16:15 - 16:35 coffee break
|
Neuroprotection
Chairpersons: C. Iadecola, W.-R. Schäbitz
PPAR as a new target for neuroprotection in cerebral ischemia
Regis Bordet (Lille, France)
Disputation on quality issues in neuroprotection research: Ninetyfive theses
Ulrich Dirnagl (Berlin, Germany)
|
Ischemic injury and repair
Chairpersons: R. Traystman, C. Culmsee
Vascular matrix adhesion and the blood brain barrier
Gregory Del Zoppo (La Jolla, USA)
Programmed necrosis induced by hopyxia-ischemia
Claude Wasterlain (Los Angeles, USA)
Bax-nucleophosmin interaction in cell death: a therapeutic target
Lorraine Kerr (Edinburgh, UK)
Toll-like receptors and tolerance in ischemic injury in the brain
Mary Stenzel-Poore (Portland, USA)
Acidotoxicity in brain ischemia
Roger Simon (Portland, USA)
10:35 - 10:55 Coffee break
|
Ischemic injury and repair
Chairpersons: K. Abe, R. Simon
Gender alters outcome from cardiac arrest/CRP
Richard Traystman (Portland, USA)
Oestrogen and stroke: The potential for harm as well as benefit
Mhairi Macrae (Glasgow, UK)
Evaluating therapeutic targets for reperfusion-related brain hemorrhage
Carolina Maier (Stanford, USA)
Molecular mechanisms underlying neurorestorative therapy of stroke
Michael Chopp (Detroit, USA)
12:35 End of meeting / Departure
|