14:00 - 18:00

Arrival and registration

08:30 - 09:15

Plenary Lecture - ATPases

John Walker (University of Cambridge, UK)

09:15 - 09:50

Using interdisciplinary approaches to elucidate the structure and function of the AAA ATPase p97/VCP

Paul Freemont (Imperial College London, UK)

09:50 - 10:25

From common molecular basis of the AAA ATPase to various energy-dependent and independent activities of AAA proteins

Teru Ogura (Kumamoto University, Japan)

10:25 - 11:00

The interaction of a novel AAA+ protein with E. coli inducible lysine decarboxylase (LdcI/CadA)

Walid Houry (University of Toronto, Canada)

11:25 - 12:00

Biochemical analysis of DnaA AAA+ domain on the ATP-dependent regulation for the initiation of chromosomal replication

Tsutomu Katayama (Kyushu University, Japan)

12:00 - 12:35

Transcription activation via AAA+ó54 activators

Xiaodong Zhang (Imperial College London, UK)

12:35 - 13:10

Structure and mechanism of an archaeal replication origin binding protein

Dale Wigley (Cancer Research UK, London, UK)

19:15 - 19:30

Selected oral communication

19:30 - 19:45

Selected oral communication

19:45 - 20:00

Selected oral communication

20:00 - 20:15

Selected oral communication

20:15 - 20:50

Structure/function studies of the bacterial enhancer binding protein NtrC1

Tracy Nixon (Penn State University, USA)

20:50 - 21:25

Structure and evolution of AAA+ domains involved in substrate recognition

Andrei Lupas (Max Planck Institute, Germany)

08:30 - 09:05

Proteasomal ATPases & neurological illnesses

John Mayer (University of Nottingham, UK)

09:05 - 09:40

Proteasomal ATPases & neurological illnesses

Jim Lowe (University of Nottingham, UK)

09:40 - 10:15

Quorum sensing in Pseudomonas aeruginosa is regulated by Lon protease

Tomoko Yamamoto (Chiba University, Japan)

10:15 - 10:50

Ubiquitination is a prerequisite for the dislocation of the PTS1-receptor Pex5p from the peroxisomal membrane by the AAA-peroxins Pex1p & Pex6p

Ralf Erdmann (Ruhr-Universitat Bochum, Germany)

11:20 - 11:55

Axons sever to survive: Spastin, microtubule severing, and Hereditary Spastic Paraplegia

Brett P Lauring (Columbia University, USA)

11:55 - 12:30

Inclusion body myopathy associated with Paget disease of bone and/or frontotemporal dementia.

Virginia Kimonis (University of California, USA)

12:30 - 13:05

Roles of VCP in human neurodegenerative disorders

Akira Kakizuka (Kyoto University, Japan)

19:15 - 19:50

Dynamic and functional assembly of the AAA peroxins, Pex1p and Pex6p, and their membrane receptor Pex26p in peroxisome biogenesis

Yukio Fujiki (Kyushu University, Japan)

19:50 - 20:25

AAA proteases, mitochondrial dysfunction, and neurodegeneration

Thomas Langer (University of Cologne, Germany)

20:25 - 21:00

Tales of AAA+ proteins, organelles, and disease

Phyllis Hanson (Washington University, St Louis, USA)

21:00 - 21:15

Carboxyterminal residues of AAA subunits of PA700, the 19S regulatory complex of the 26S proteasome, mediate binding to activation of the 20S proteasome

George De Martino (University of Texas, USA)

21:15 - 21:30

Selected oral communication

08:30 - 09:05

Archaeal DnaA and Drosphila ORC

James Berger (Lawrence Berkeley National Laboratory, USA)

09:05 - 09:40

Replication, repair, and chromatin access in S. pombe

Susan Forsburg (University of Southern California, USA)

09:40 - 10:15

Mechanism of protein disaggregation by AAA chaperones

Bernd Bukau (ZMBH Heidelberg, Germany)

10:15 - 10:30

Selected oral communication

10:30 - 10:45

Selected oral communication

11:15 - 11:50

Protein unfolding during degradation by the proteasome

Andreas Matouschek (Northwestern University, USA)

11:50 - 12:25

Clps and proteases

Mike Maurizi (National Cancer Institute, USA)

12:25 - 13:00

Role of VCP/p97 in nucleus formation after mitosis

Hemmo Meyer (ETH Zurich, Switzerland)

14:30 - 15:05

p97/Cdc48 function

Martin Latterich (McGill University, Canada)

15:05 - 15:40

Role of ATPases in controlling substrate entry into the proteasome

Alfred Goldberg (Harvard Medical School, USA)

15:40 - 15:55

Selected oral communication

08:30 - 09:05

The AAA+ ATPase ring and microtubule-binding site of dynein, an AAA+ molecular motor, communicate through a long coiled-coil

Kazuo Sutoh (University of Tokyo, Japan)

09:05 - 09:40

Mechanism of DNA translocation in a replicative hexameric helicase

Leemor Joshua-Tor (Cold Spring Harbour Laboratory, USA)

09:40 - 09:55

Selected oral communication

09:55 - 10:10

Selected oral communication

10:10 - 10:25

Selected oral communication

10:25 - 10:40

Selected oral communication

11:20 - 11:35

Selected oral communication

11:35 - 11:50

Selected oral communication

11:50 - 12:05

Selected oral communication

12:05 - 12:20

Selected oral communication

12:20 - 12:35

Selected oral communication

12:35 - 12:50

Selected oral communication