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PI3-K in the Immune System

9—10 September 2002

Novartis, Horsham, UK



Timetable

Monday 9 September 2002Tuesday 10 September 2002
10:30 - 17:30
PI3-K in the Immune System

09:30 - 12:40
PI3-K in the Immune System


PI3-K in the Immune System

Organizers:
Melanie Welham (Bath, UK)
Peter Finan (Novartis, UK)
Stephen Ward (Bath, UK)
Sponsors:
The Biochemical Society
New England Biolabs
GlaxoSmithKline
Novartis
ICOS
Pfizer
Serono Pharmaceuticals

Biology and Regulation

Monday 9 September 2002
09:30 - 10:30 Registration

10:30 - 11:00
Uncovering the complexity of inositol phospholipid dependent cellular signals
Peter Downes (Dundee, UK)
11:00 - 11:40
Impaired B and T cell antigen receptor signalling in p110dPI3-Kinase mutant mice
Bart Vanhaesebroeck (Ludwig Institute for Cancer Research, UK)
11:40 - 12:20
PI3-Kinase g - a key modulator in inflammation and allergy
Matthias Wymann (Fribourg, Switzerland)
12:20 - 13:40 Lunch and Poster Session One

13:40 - 14:20
Signalling via PI3-Kinases in neutrophils
Phill Hawkins (Babraham Institute, Cambridge, UK)
14:20 - 15:00
SHIPs and Doks as regulators of immune cell function
John Cambier (Denver, CO, USA)
15:00 - 15:40
The role of SHIP in mast cells and macrophages
Gerry Krystal (Vancouver, Canada)
15:40 - 16:00 Tea/Coffee Break

16:00 - 16:40
Role of p110d in neutrophil function
Joel Hayflick (ICOS Corporation, USA)
17:30 - 19:00 Drinks Reception and Poster Session Two

19:30 - 23:00 Meeting Dinner (Ghyll Country Manor Hotel)

Oral communications from elevated abstracts

Monday 9 September 2002
12:20 - 13:40 Lunch and Poster Session One

15:40 - 16:00 Tea/Coffee Break

16:40 - 16:55
A role for PI3-K in thymocyte positive selection
Susannah D. Barbee (California Institute of Technology, USA)
16:55 - 17:10
The role of PI3-Kinase-gamma in murine neutrophil chemotaxis and function during airway inflammation
Matthew Thomas (Novartis, UK)
17:10 - 17:30
Targeting chemokine signaling - An innovative therapeutic strategy
Christian Rommel (Serono Pharmaceutical Research Institute, Switzerland)
17:30 - 19:00 Drinks Reception and Poster Session Two

19:30 - 23:00 Meeting Dinner (Ghyll Country Manor Hotel)

Downstream Effectors in Immune Cells

Tuesday 10 September 2002
09:00 - 09:30 Registration

09:30 - 10:10
Cytokine-mediated control of proliferation and survival through regulation of Forkhead transcription factors
Paul Coffer (Utrect, The Netherlands)
10:10 - 10:50
S6 Kinase signalling and cell growth
George Thomas (Fredrich Miescher Institute, Switzerland)
10:50 - 11:20 Tea/Coffee Break

11:20 - 12:00
Signalling and its consequences in T cells
Doreen Cantrell (Cancer Research UK, London, UK)
12:00 - 12:40
Regulation of the protein kinase b/akt signalling pathway
Brian Hemmings (Fredrich Miescher Institute, Switzerland)
12:40 - 13:40 Lunch

13:40 Meeting Close