Organizers:
Barbara Reaves (University of Bath, UK)
Adrian Wolstenholme (University of Bath, UK)
David Beech (University of Leeds, UK)
Timetable
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Session One
Thursday 7 September 2006
10:00 - 11:00 Registration with coffee/tea
11:00 - 11:05 Welcome and Introduction
Function and regulation of TRPC1
Indu Ambudkar (National Institutes of Health, USA)
Intramembrane domains controlling the selectivity of TRPV1 channel assembly
Michael Schaefer (Max-Delbrueck-Center for Molecular Medicine, Germany)
Implication of the N- terminal and pore region of TRPC in the channel assembly
Selected oral communication - Guylain Boulay (Université de Sherbrooke, Canada)
TRPV5 and TRPV6 in calcium (re)absorption: regulating calcium entry at the gate
Rene Bindels (Radbout University of Nijmegen, The Netherlands)
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Session Two
Thursday 7 September 2006
Drosophila TRP and TRPL channels
Roger Hardie (University of Cambridge, UK)
TRPM channel function in Caenorhabditis elegans
Howard Baylis (University of Cambridge, UK)
TRPM3 - a novel endocrine steroid receptor
Selected oral communication - Johannes Oberwinkler (Uniklinikum des Saarlandes, Germany)
15:25 - 16:00 Coffee/tea break
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Session Three
Thursday 7 September 2006
TRP channels and kidney disease-lessons from polycystic kidney disease
Richard Sandford (University of Cambridge, UK)
TRPC channels promote cerebellar granular neuron survival
Selected oral communication - Yizheng Wang (Institute of Neuroscience, China)
Differential role of TRP channels in prostate cancer
Selected oral communication - Natalia Prevarskaya (University of Lille, France)
Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow
Selected oral communication - Elena Oancea (Harvard Medical School, USA)
TRP channels: from sensory signalling to human disease
Craig Montell (Johns Hopkins University, USA)
19:00 - 20:00 Meeting Dinner
20:00 - 23:00 Poster session with refreshments
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Session Four
Physiological function of receptor-operated cation entry via TRPC channels
Thomas Gudermann (University of Marburg, Germany)
The C-terminal domain of hTRPC1, hTRPC3 and hTRPC7 determines targeting to intracellular compartments
Selected oral communication - Barbara Reaves (University of Bath, UK)
Novel activation mechanisms and functions of TRPC
David Beech (University of Leeds, UK)
10:25 - 11:00 Coffee/tea break
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Session Five
Activation and modulation of thermosensitive TRP channels
Stuart Bevan (Novartis, UK)
Role of an intracellular coiled coil in formation of TRPM2 channels
Selected oral communication - Lin-Hua Jiang (University of Leeds, UK)
TRP channels activated by extracellular hypotonicity
Christian Harteneck (Charité-Universitätsmedizin Berlin, Germany)
Activation of T cell calcium influx by the second messenger ADP-ribose
Andreas H. Guse (University Medical Center Hamburg-Eppendorf, Germany)
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Session Six
Physiological functions of TRPCs
Marc Friechel (University of Saarlandes, Germany)
TRPC1 modulates TRPV6 channel activity
Selected oral communication - Rainer Schindl (Johannes Kepler Universität, Austria)
Regulation of TRP channels: a lipid-voltage connection
Bernd Nilius (Catholic University of Leuven, Belgium)
15:25 - 15:30 Summary and conclusions
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