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2nd Joint German/UK Bioenergetics Conference - Integration of structures, spectroscopies and mechanisms

2—4 April 2008

University of Edinburgh, UK



Organizers:
Peter Rich (University College London, UK)
Steve Chapman (University of Edinburgh, UK)
Peter Heathcote (Queen Mary, University of London, UK)
John Ingledew (University of St. Andrews, UK)
Mike Jones (University of Bristol, UK)
Fraser MacMillan (University of East Anglia, UK)
John Walker (Medical Research Council, UK)
Ulrich Brandt (University of Frankfurt, Germany)
Bernd Ludwig (University of Frankfurt, Germany)
Hartmut Michel (Max-Planck Institute of Biophysic, Germany)

Special Events

Wednesday 2 April 2008
17:45 - 18:45
The Keilin Memorial Lecture
Hartmut Michel (Max-Planck Institute of Biophysic, Germany)

The Keilin Memorial Lecture

Chair:
Peter Rich (University College London, UK)
Wednesday 2 April 2008
15:30 - 17:30 Registration

17:45 - 18:45
The Keilin Memorial Lecture
Hartmut Michel (Max-Planck Institute of Biophysic, Germany)
17:45 - 18:45
The Keilin Memorial Lecture
Cytochrome c oxidase: structures, surprises and revolutions
Hartmut Michel - The Keilin Memorial Lecture (Max-Planck Institute of Biophysic, Germany)
19:00 - 20:00 Dinner

20:00 - 21:00 Drinks reception

Light activated systems

Chairs:
Peter Heathcote (Queen Mary, University of London, UK)
Mike Jones (University of Bristol, UK)
Thursday 3 April 2008
09:00 - 09:30
Structure and mechanism of membrane transporters
So Iwata (Imperial College London, UK)
09:30 - 10:00
Recent progress on the architecture of cyanobacterial photosystem II at 2.9 Å resolution
Wolfram Sänger (Freie Universität Berlin, Germany)
10:00 - 10:30
Structural analysis of the RC-LH1-PufX dimer complex of Rhodobacter sphaeroides by NMR, cryo-EM and single particle reconstruction
Neil Hunter (University of Sheffield, UK)
10:30 - 11:00 Coffee/tea break

11:00 - 11:30
Significance of protein crowding, order and mobility for photosynthetic membrane functions
Helmut Kirchhoff (Westfälische Wilhelms-Universität Münster, Germany)
11:30 - 12:00
Protein-bound waters in catalysis
Klaus Gerwert (Ruhr-Universität Bochum, Germany)
12:00 - 12:15
Ferroplasma acidiphilum and Acidithiobacillus ferrooxidans, two iron-oxidizing acidophiles living in extreme environnement
Selected oral communication - Cindy Castelle (IBSM-CNRS, Marseille, France)
12:15 - 12:30
Clustering and dynamics of the Escherichia coli cytochrome bd terminal quinol oxidase in vivo
Selected oral communication - Yueng Tchern Lenn (Queen Mary, University of London, UK)
12:30 - 13:30 Lunch

Electron transfer - Part I

Chairs:
Peter Rich (University College London, UK)
Ulrich Brandt (University of Frankfurt, Germany)
Thursday 3 April 2008
14:30 - 15:00
Substrate-induced conformational changes in the Escherichia coli NADH: ubiquinone oxidoreductase (complex I)
Thorsten Friedrich (Albert-Ludwigs-Universität Freiburg, Germany)
15:00 - 15:30
Structural studies on bacterial respiratory complex I
Leo Sazanov (University of Cambridge, UK)
15:30 - 16:00
How does mitochondrial complex I produce superoxide?
Judy Hirst (University of Cambridge, UK)
16:00 - 16:30 Coffee/tea break

16:30 - 17:00
X-ray structural studies on bc1 complex
Carola Hunte (University of Leeds, UK)
17:00 - 17:30
Bioenergetics at the gold surface: SEIRAS probes photosynthetic and respiratory reactions at the monolayer level
Joachim Heberle (Bielefeld University, Germany)
17:30 - 18:00
Structure and function of the ATP synthase
John Walker (Medical Research Council, UK)
18:00 - 19:00 Poster session and drinks reception

19:00 Meeting dinner and Bar facilities

Electron transfer - Part II

Chair:
Stuart Ferguson (University of Oxford, UK)
Friday 4 April 2008
09:00 - 09:30
A novel electron-transfer pathway in Rhodobacter sphaeroides
Steve Chapman (University of Edinburgh, UK)
09:30 - 10:00
Electroneutral and electrogenic catalysis by dihaem-containing succinate: quinone oxidoreductases
Roy Lancaster (Saarland University, Homburg, Germany)
10:00 - 10:30
The mechanism of haem copper oxidases as studied by EPR spectroscopy
Fraser MacMillan (University of East Anglia, UK)
10:30 - 11:00 Coffee/tea break

11:00 - 11:30
EPR spectroscopy on the donor side of photosystem II
Robert Bittl (Freie Universität Berlin, Germany)
11:30 - 12:00
The structure and function of multiheme cytochromes involved nitrite, nitric oxide and iron respiration
Thomas Clarke (University of East Anglia, UK)
12:00 - 12:30
Novel quinol dehydrogenases involved in respiratory nitrate ammonification
Jörg Simon (Johann Wolfgang Goethe-Universität, Germany)
12:30 - 13:30 Lunch

ATPases and transporters

Chairs:
John Ingledew (University of St. Andrews, UK)
Peter Gräber (Universität Freiburg, Germany)
Friday 4 April 2008
13:30 - 14:00
Spectroscopic and structural studies of the alternative oxidase
Anthony Moore (University of Sussex, UK)
14:00 - 14:30
Domain compliance and elastic power transmission in FOF1-ATPase
Wolfgang Junge (University of Osnabrück, Germany)
14:30 - 15:00
Structure of the V-ATPase by electron microscopy and image processing
Bettina Böttcher (European Molecular Biology Laboratory Heidelberg, Germany)
15:00 - 15:30 Coffee/tea break

15:30 - 16:00
Substrate recognition and transport mechanism of mitochondrial carriers
Edmund Kunji (University of Cambridge, UK)
16:00 - 16:30 General discussion and closing remarks