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Bioanalysis in oxidative stress

2—3 April 2008

University of Exeter, UK



Organizers:
John Moody (University of Plymouth, UK)
Paul Winyard (University of Exeter, UK)
RSC
Wednesday 2 April 2008
12:00 - 14:05 Registration and lunch

14:05 - 14:45
Protein mass spectrometry and the identification of post-translational modifications
Simon Gaskell (University of Manchester, UK)
14:45 - 15:25
High-resolution mass spectrometry and inactivation of protein targets during oxidant stress
Stephen Barnes (University of Alabama, USA)
15:25 - 15:40
Identification of thioredoxin targets using a quantitative proteomics approach based on isotope-coded affinity tags
Selected oral communication - Per Hägglund (Technical University of Denmark, Denmark)
15:40 - 16:05 Coffee/tea break

16:05 - 16:45
Protein post-translational modifications related to oxidative stress
Catherine Costello (Boston University, School of Medicine, USA)
16:45 - 17:25
Measurement of nitrosative stress, including 3-nitrotyrosine by MS
Kevin Moore (University College London, UK)
17:25 - 17:40
A functional ¿chloroproteomics¿ approach to study cell death at sites of chronic inflammation
Selected oral communication - Matt Whiteman (Peninsula Medical School, Exeter, UK)
17:40 - 19:00 Drinks reception and poster session 1 (odd numbers)

19:30 - 21:00 Gala dinner

Thursday 3 April 2008
09:05 - 09:45
Quantitation of markers of protein glycation, oxidation and nitration in cellular and extracellular proteins and body fluids
Paul Thornalley (University of Warwick, UK)
09:45 - 10:25
Mass spectrometry to detect and identify post-translational modifications of protein
Jenny Ames (Queen's University Belfast, Ireland)
10:25 - 10:40
Measurement of N-(Carboxymethyl)lysine (CML) and N-(Carboxyethyl)lysine (CEL) in human plasma protein by stable-isotope-dilution tandem mass spectrometry (MS) on a Quattro Premier
Selected oral communication - Jean Scheijen (University Hospital Maastricht, The Netherlands)
10:40 - 11:05 Coffee/tea break

11:05 - 11:45
Analysis of eicosanoids and related lipid mediators using mass spectrometry
Ben Maskrey (Cardiff University, UK)
11:45 - 12:25
Correlations between F2-isoprostanes and other biomarkers of oxidative stress: analytical aspects
Jaffar Nourooz-Zadeh (Urmia University of Medical Sciences, Iran)
12:25 - 12:40
Ion-trap tandem mass spectrometric analyses of blood plasma phosphatidylcholine hydroperoxides and skin squalene hydroperoxides
Selected oral communication - Teruo Miyazawa (Tohoku University, Japan)
12:40 - 14:00 Lunch and poster session 2 (even numbers)

14:00 - 14:40
Mass spectroscopy for vitamin E research: stable-isotope and metabonomic approaches
John Lodge (University of Surrey, UK)
14:40 - 15:20
Oxidative DNA to damage
Steffen Loft (University of Copenhagen, Denmark)
15:20 - 15:35
Capillary electropohoretic analysis of 8-oxoG and 8OHdG
Selected oral communication - Blánaid White (Dublin City University, Ireland)
15:35 - 16:00 Coffee/tea break

16:00 - 16:40
Analysis of HOCl- and free radical-induced damage to biomolecules by LCMS
Corinne Spickett (University of Strathclyde, UK)
16:40 - 16:55
A novel marker of inflammation formed in the lungs of premature infants and children with cystic fibrosis
Selected oral communication - Tim Harwood (University of Otago, New Zealand)
18:30 - 20:00 Dinner