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Intracellular Ion Channels and Insulin Secretion (I)
Organizer:
Guy A. Rutter (Bristol, UK)
Sponsors:
The Physiological Society
Introduction - Guy Rutter (Bristol, UK)
Pharmacological modulation of ATP-sensitive K-channels
Fiona Gribble (Cambridge, UK)
Structure and function relationships in the beta-cell KATP channel
Steve Ashcroft (Oxford, UK)
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Intracellular Ion Channels and Insulin Secretion (II)
Hyper-insulinism and KATP channels
Mark Dunne (Sheffield, UK)
Molecular mechanisms involved in secretory vesicle recruitment to the plasma membrane in beta cells
Aniko Varadi (Bristol, UK)
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Genes and Development
The genetics of the beta-cell: lessons from maturity-onset diabetes of the young
Tim Frayling (Exeter, UK)
Differentiation of ES-Cells into insulin-secreting cells
Marcus Stoffel (Rockefeller Institute, New York, USA)
Role of insulin- and IGF-1-receptors in the islet function
Rohit Kulkarni (Joslin Diabetes Center, Boston, USA)
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Nutrient Regulation of Gene Expression
15:00 - 15:20 Tea/ Coffee Break
Role of AMP-activated kinase in the regulation of gene transcription
Isabelle Leclerc (Alberta, Edmonton, Canada)
Insulin stimulated gene expression in the pancreatic beta-cell
Barbara Leibiger (Karolinska Institute, Stockholm, Sweden)
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