Subcellular location of PKCalphaII-GFP (green) in Green Monkey COS-7 cells using laser scanning confocal microscopy two days after transfection. The actin cytoskeleton is stained with Texas Red-phalloidin and the endoplasmic reticulum (purple) identified with an antibody to calreticulin.   By Lorene Langeberg, Scott Lab Manager at the Howard Hughes Medical Institute, Portland, OR.
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Summer Vacation Studentship Reports

Deadline for the next round of Studentships: 13 February 2009

Student's reports (2006 round)

Ten summer vacation studentship applications were awarded a total of £14,560 worth of funding in 2006.

1 A study to determine the potential of Defolliculated as a model system for understanding the pathology of autoimmune disorders. (image)
Supervisor: Dr Rebecca Porter Cardiff University
Student: John Mason Department of Dermatology

2The effect of S.aureus derived peptidoglycans on the endothelial gap junction network
Supervisor:Dr Patricia MartinGlasgow Caledonian University
Student:Ann-Marie AllenDepartment of Biomedical Sciences

3The role of PINK1 in the development of diabetes mellitus
Supervisor:Dr James Timmons Karolinska Institute
Student: Robert Brogan Centre from Molecular Biology

4Modulation of MRP4 transport by interaction with dietary flavonoids and the role of glutathione (GSH)
Supervisor:Dr Alice Rothnie Queen's University, Kingston
Student: Kate Starr Cancer Research Institute

5Kinetics of Inhibitor Binding to Heat-shock protein 90
Supervisor:Dr Sophie Elizabeth Jackson University of Cambridge
Student: Shreyas Ram Mukund Department of Chemistry

6Whether the interaction of cytochrome c with cardiolipin overcomes this kinetic limitation
Supervisor:Professor Chris Cooper University of Essex
Student: Rebecca Holladay Department of Biological Sciences

7The transient expression of G-protein Coupled Receptor Proteins using the agrobacterium-mediated transfection of Nicotiana Benthamiana
Supervisor:Dr Philip Reeves University of Essex
Student: Kieron South Department of Biological Sciences

8Localisation and topology of atToc12, a stromal co-chaperone
Supervisor:Dr Paul Jarvis University of Leicester
Student: Nicholas Putz Department of Biology

9Studies of the interactions of Annexin-53 with artificial and cellular membranes; possible effects on raft structures
Supervisor:Professor Paul O'Shea University of Nottingham
Student: Benjamin Davis Cell Biophysics Group

10To produce a system for studying the effect of Diamond Blackfan Anaemia patient mutations in the RPS19 gene when expressed in the human cell line HeLa.
Supervisor:Dr Philip Mason Washington University
Student: Emma Hall Hematology Division

 




Student's reports (2007 round)

This summer 15 excellent undergraduate life scientists (and their supervisors) were awarded studentships to experience 10 weeks in the lab. Tough competition surrounded the application deadline and the review panel struggled to pick out the best project structures, students and science. The chosen hypotheses, battled with over the summer break, surrounded many areas of cutting edge biochemical research with project topics ranging from osteoporosis, cancer therapies and diabetes to environmental toxicology and bacteria-aided digestion. Placements like these involve hard work from both student and supervisor but there are many rewards. What better chance for undergraduates to gain insight into the world of The Lab where ‘problem solving leads to achievement… or a dead end’? What better chance for supervisors to inspire these talented students to continue into scientific research after graduation and for them, orchestrate a mini-project to tackle the ‘problem of the moment’?

Read these 15 exciting accounts of projects put together by 15 established members of the Biochemical Society’s network, executed by 15 new ones.

In preparation for next years round of applications (deadline: 29 February 2008) the Society has increased the funding to £40,000 to help satisfy the demand for even more of these worthwhile studentships. In addition to the stipend, students also receive 3 years membership to the Biochemical Society.

Apply now

Fifteen summer vacation studentship applications were awarded a total of £21,120 worth of funding in 2007.

1 A novel mechanism for zinc-regulated gene expression – investigation of proteins binding to the 3’UTR of the human zinc transporter ZnT5
Supervisor:Dr Dianne Ford University of Newcastle
Student: Marc Flanagan School of Cell and Molecular Biosciences

2 Generation of SecYEG – peptide complexes for structural analysis.
Supervisor:Dr Ian Collinson University of Bristol
Student: Mei Sun Department of Biochemistry

3 Deletion of dimethylarginine dimethylaminohydrolase (DDAH) in a stem cell line using siRNA.
Supervisor:Dr Caroline Smith University of Westminster
Student: Alex Mclatchie School of Biosciences

4 Protein-DNA interactions at the extreme.
Supervisor:Dr Richard Bowater The University of East Anglia
Student: Hung Bui School of Biological Sciences

5 Characterisation of p53 mutant proteins.
Supervisor:Dr Penka Nikolova King's College London
Student: Hellen Houlleberghs Department of Biochemistry

6 Investigating the role of Integrin in c-Met signalling.
Supervisor:Dr Stéphanie Kermorgant Queen Mary, University of London
Student: Victoria Eades Department of Tumour Biology

7 Anti-oxidant enzymes produced by coral-associated bacteria.
Supervisor:Dr John Moody University of Plymouth
Student: Hannah Marchant School of Biological Sciences

8 Investigation into whether the interaction between HIPK1 and BCL11A is SUMO-dependant, using HIPK1 mutants, several BCL11A constructs and the yeast-two hybrid assay.
Supervisor:Dr Cristina Montiel-Duarte Nottingham University
Student: Emily Golding School of Pharmacy

9 Inhibition of transcription factor interactions using small molecules.
Supervisor:Dr Ian Wood The University of Leeds
Student: Matthew McArdle Institute of Membrane and Systems Biology

10 Regulation of the DNA damage checkpoint in plants.
Supervisor:Dr Hilary Rogers Cardiff University
Student: Nuramizah Amiruddin School of Biosciences

11 Identification of the biochemical pathways for histone methylation induced by nuclear envelope (NE) protein NET23.
Supervisor:Dr Poonam Malik University of Edinburgh
Student: Ravi Badwe Wellcome Trust Centre for Cell Biology

12 The biological rationale for the expansion of glycoside hydrolase families in Bacteroides Thetaiotaomicron.
Supervisor:Professor Harry Gilbert University of Newcastle
Student: Andrew Thompson Institute for Cell and Molecular Biosciences

13 Evaluation of anti-cancer activity of dietary indoles in combination with specific inhibitors of tyrosine kinases EGFR, Her2 and Src.
Supervisor:Professor Margaret Manson University of Leicester
Student: Nikolay Ogryzko Department of Biochemistry and Department of Cancer Studies and Molecular Medicine

14 Expression and functional significance of dopamine signalling systems in pancreatic b cells.
Supervisor:Professor Peter Jones King's College London
Student: Andrea Fernandes Guy's Campus

15 The role of release factors in a novel translational recoding event.
Supervisor:Dr Jeremy Brown University of Newcastle
Student: Terri Victoria Cornforth The Medical School

For more information on summer vacation studentships please email profeducat@biochemistry.org


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