Cellular delivery of therapeutic macromolecules - A Biochemical Society Focused Meeting in association with the Royal Society of Chemistry, the Royal Pharmaceutical Society of Great Britain and the Academy of Pharmaceutical Sciences

Cardiff University, UK

29 - 31 August 2006

POSTER ABSTRACTS

Abstracts first published on the Internet 15 August 2006

P001 Peptide-based nanoparticles for in vivo delivery of siRNA targeting Cyclin B1

M.-C. Morris, F. Simeoni, G. Aldrian-Herrada, Q. Nguyen, G. McMaster, F. Heitz and G. Divita

P002 Nanoparticles oligonucleotide complexes for the treatment of EWS/Fli-1 expressing tumours in mice

C. Malvy, A. Maksimenko, J.R. Bertrand, N. Toub and P. Couvreur

P003 Transfection of retinal pigment epithelium with pegylated Lipoplexes

L. Peeters, N. N. Sanders, J. Demeester and S.C. De Smedt

P004 Combinatorial selection, delivery and anti-viral activity of backbone modified oligonucleotide aptamers against HIV-1 RT

V. Thiviyanathan, A. Somasunderam, M. Ferguson, D. Rojo, W. O’Brien and D. Gorenstein

P005 Effects of temperature on intracellular distribution of cell-penetrating peptides

M.M.F retz, N.A. Penning, S. Al-Taei, G. Storm, S. Futaki and A.T. Jones

P006 Nebulizer-assisted chemical transfection

A. Unciti-Broceta, J.J. Díaz-Mochón and M. Bradley

P007 Synthetic PNA-peptide conjugates as inhibitors of HIV-1 Tat-dependent trans-activation in cells

J. Turner, A. Arzumanov, G. Ivanova, D. Owen, D. Williams, S. Abes, B. Lebleu and M.J. Gait

P008 Microneedle facilitated delivery of pDNA to the epidermis

M. Pearton, C. Gateley, A. Anstey, N. Wilke, A. Morrissey, C. Allender, K. Brain and J.C. Birchall

P009 Chitosan-coating of liposomes to enhance cellular drug delivery

L. Kudsiova and J. Lawrence

P010 Abstract Withdrawn.

P011 Lipidic peptide dendrons for delivery of macromolecules

C. Ramaswamy, A.F. Wilderspin and A.T. Florence

P012 Cellular delivery of siRNA by a non-covalently attached peptide: quantitative analysis of uptake and biological effect.

S. Laufer, S. Veldhoen, A. Trampe and T. Restle

P013 Reorganisation of the endocytic pathways of multidrug resistant cells

J. Jin and A.T. Jones

P014 Evaluation of 60 nm nanoparticles as delivery systems of proteins on an in vitro model of blood brain barrier

Y. Jallouli, A. Paillard, R. Cecchelli and D. Betbeder

P015 CADY: a new generation of secondary amphipathic peptides for the delivery of siRNA

A. Charnet, L. Crombez, G. Aldrian-Herrada, R. Brasseur, F. Heitz and G. Divita

P016 Vectorization of morpholino oligomers by the (R-Ahx-R)4 peptide allows efficient splicing correction in the absence of endosomolytic agents

S. Abes, H.M. Moulton, P. Clair, P. Prevot, D.S. Youngblood, R.P. Wu, P.L. Iversen and B. Lebleu

P017 Novel cell adhesion compounds immobilise dendritic cells and allow efficient phagocytosis

A. Mant, J.J. Diaz-Mochon, G. Tourniaire, A.P. Williams, T.J. Elliott and M. Bradley

P018 Targeted delivery of clostridial endopeptidase

C.J. Cruttwell, Y. Hall, E.J. Adams, L.J. Durose, E.M. Marks, J.A. Chaddock, D.F. Rogers and K.A. Foster

P019 Transcriptional effects of delivery systems: the effect of dendrimer architecture on EGFR mRNA expression and on siRNA-mediated gene silencing activity

A. Hollins, Y. Omidi, M. Benboubetra and S. Akhtar

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