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Biochemical Society Annual Symposium - Structure and function in cell adhesion

3—5 December 2007

The Palace Hotel, Manchester, UK



4 December 2007

Poster Session 1: 14:00 - 15:30


P001 Highly controlled surface presentation of protein signalling motifs to regulate cell behaviour
E. Mitchell, J. Lakey and M. Birch
P002 Integrin avb3 lateral clustering promotes focal adhesion stability and fibronectin matrix organization
E.A. Cavalcanti-Adam, M. Dragovits, M.-O. Diesner and J. Spatz
P003 Generation and analysis of a mouse mutant deficient for the adhesion molecule MAdCAM-1
A. Schippers, C. Leuker, O. Pabst, A. Kochut, A.D. Gruber, N. Wagner and W. Müller
P004 Focal adhesion kinase inhibits anoikis by influencing Bax subcellular localisation
J.A. Keeble, N.K. Zouq and A.P. Gilmore
P005 The adhesion molecule ICAM-2 regulates contact inhibition in endothelial cells (EC)
V. Amsellem, N. Dryden, G.M. Birdsey, D.O. Haskard, J. Mason and A.M. Randi
P006 The molecular assembly of the area composita of adhering junctions connecting mammalian cardiomyocytes: the special importance of plakophilin-2
S. Pieperhoff, C. Grund and W.W. Franke
P007 The molecular and cell biological characterization of a novel type of adhering junction in transformed mesenchymal cells
S. Rickelt, S. Winter-Simanowski, C. Kuhn and W.W. Franke
P008 An RNAi screen to identify regulators of F-actin associated with adherens junctions
A.P. Wheeler and V.M.M. Braga
P009 The effect of adrenaline on monocyte adhesion in obesity and insulin resistance
M. Sarigianni, K. Paletas, M. Kaloyianni, E. Kostidou, A. Tsapas and G. Koliakos
P010 The molecular characterization of the adhering junctions connecting the interstitial cells of the cardiac valves: postulate of dissociative forces and the formation of a supracellular meshwork by tentacle-like cell processes
M. Barth and W.W. Franke
P011 P-cadherin and E-cadherin-expressing breast carcinomas are associated with cytoplasmic p120-catenin and poor patient survival
A.L. Correia, J. Paredes, A.S. Ribeiro, F. Milanezi and F. Schmitt
P013 Functional analysis of human d-protocadherin 11 (PCDH11) and its implications in the progression of cancer
U. Fuchs, K. Staes and F. van Roy
P014 Spatiotemporal regulation of vinculin in cell-cell junction
Q. le Duc and J. de Rooij
P015 Regulation of hyaluronan binding to the lymphatic receptor LYVE-1
M. Frayne, T. Nightingale, S. Clasper and D. Jackson
P016 The CellHesion - quantifying adhesion forces between single cells
K. Poole, G. Behme, H. Haschke and R. Owen
P017 Blockade of VCAM1 and ICAM1 inhibits CD8? T cell response to virus at the level of translymphatic migration
L.A. Johnson, D. Teoh, A.J. McMichael and D.G. Jackson
P018 An unusual glycosaminoglycan-binding domain in the lymphatic endothelial hyaluronan receptor LYVE-1
S. Banerji, B. Hide, T. Nightingale, R. Prevo, M. Noble and D.G. Jackson
P020 The extracellular matrix modulates interleukin-1 production and actions in rodent glial cells
L. Summers, C. Kielty and E. Pinteaux
P022 Direct association of transglutaminase-2 with syndecan-4 in the formation of RGD-independent focal adhesions on fibronectin
A. Scarpellini, R. Germack, T. Johnson, T. Muramatsu, M. Griffin and E. Verderio
P023 Mechanisms of dissociation of E-cadherin-mediated junctions in enterocytes undergoing anoikis: the role of the epidermal growth factor receptor
V.-H. Lugo-Martínez, C. Petit, S. Fouquet, J. Chambaz, M. Pinçon-Raymond, P. Cardot and S. Thenet
P024 The association of aggrecan polymorphism in degeneration of intervertebral disc
F. Mashayekhi, Z. Salehi and G.R. Shafeei
P025 The role of non-conserved active site residues in substrate specificity of AOC3
H. Elovaara, H. Kidron, T.A. Salminen, M. Salmi and S. Jalkanen
P026 Localisation of the cytoplasmic sub-domains of the desmosomal cadherin desmoglein 2
A. Scothern and D. Garrod
P027 Forced rupture of the neural cell adhesion molecule complex
V. Maruthamuthu, K. Schulten and D.E. Leckband
P028 Renal allograft rejection: chemokines enhance the affinity of adhesive CD103? T cell interaction with the specific ligand E-cadherin
A. Al-hamidi, S. Ali and J. Kirby
P029 Uncoupling of Src-induced morphological and oncogenic transformation by distinct integrin domains
S. Huveneers, A. Sonnenberg and E.H.J. Danen
P030 Vinculin orchestrates cell-matrix interactions via talin and actin
J.D. Humphries, P. Wang and C. Ballestrem
P031 Cell-tenascin-X interaction: modification of structure and signaling within adhesion sites
A. Carisey, C. Lethias, J.-Y. Exposito and C. Cluzel
P032 Control of ligand binding in the talin rod
M. Himmel, A. Ritter, K. Rottner, A.R. Gingras and W.H. Ziegler
P033 Regulation of platelet-derived growth factor receptors by cell-matrix interactions in mesenchymal stem cells
J. Veevers, S. Ball and C. Kielty
P034 Generation and analysis of mice with mutations in the b7-integrin gene
A. Kochut, W. Müller and A. Schippers
P035 Syndecan-4-dependent GTPase regulation determines directional migration in response to the extracellular matrix
M. Bass, K. Roach, M. Morgan and M. Humphries
P036 Exploring the interaction of integrin a1b1 with phospholipase Cg1
K. Tang, C. Smerling, W. Hofmann, C. Freund and K. Danker
P037 Increased monocyte attachment to laminin in diabetes mellitus. The role of the a2 and aL integrin subunits
E. Kostidou, G. Koliakos and M. Kaloyianni
P038 Proteomic analysis of integrin-based protein complexes
J.D. Humphries, A. Byron, D. Knight, S.E. Craig, S.B. Ludbrook and M.J. Humphries
P039 Dystroglycan function in prostate cancer
A. Mitchell and S. Winder
P040 Opticin is an endogenous inhibitor of angiogenesis that interacts with the a2b1 integrin
M.M. Le Goff, M.J. Humphries and P.N. Bishop
P041 The “linker” region (aa 38-47) of the disintegrin elegantin is a novel inhibitory domain of integrin a5b1-dependent cell adhesion on fibronectin
R. Sumathipala, C. Xu, J. Seago, A.P. Mould, M.J. Humphries, S.E. Craig, Y. Patel, E.S. Wijelath, M. Sobel and S. Rahman
P042 An integrin-containing muscle adhesion complex opposes muscle protein degradation in C. elegans
E. Oczypok and N.J. Szewczyk
P043 The structure of the F0F1 double domain of the talin head
B.T. Goult, P.R. Elliott, N. Bate, A.R. Gingras, J.G. Grossmann, G.C.K. Roberts, I.L. Barsukov and D.R. Critchley
P044 Deletion of integrin a3b1 in skin promotes wound healing
C. Margadant, K. Raymond, M. Kreft, H. Janssen and A. Sonnenberg
P045 The elongated and modular organization of fibronectin revisited by the structure of its 45kDa gelatin binding domain
M. Graille, M. Pagano, T. Rose, M. Reboud Ravaux, D. Liger and H. van Tilbeurgh
P046 Nerve growth factor induces chondroitin sulfate expression in the developing chicken brain tissue
F. Mashayekhi and Z. Salehi
P047 Alteration of heparan sulphate composition during inflammation
J. Spielhofer, K. Lehner, J.A. Kirby and S. Ali
P048 Testican expression in the developing cerebral cortex
Z. Salehi, F. Mashayekhi and N. Nouri
P049 Administration of anti-testican antibody in the cerebrospinal fluid increases neural cell death in the developing mouse cerebral cortex
Z. Salehi and F. Mashayekhi
P050 Structure and extension of fibrillin microfibrils
M.-C. Wang and C. Baldock
P051 A role for syntenin in syndecan 1 mediated formation of filopodia
B. Sulka, F. Letourneur and P. Rousselle
P052 Interplay between integrin subunits in signaling
J. Jokinen, D. White, W. Connors, S. Puranen, L. Nissinen, P. Kankaanpää, M. Johnson and J. Heino
P053 Molecular force spectroscopy of homophilic nectin-1 interactions
T.S. Lim, S.R.K. Vedula, S. Hui, J.P. Kausalya, B. Lane, G. Rajagopal, W. Hunziker and C.T. Lim
P054 A tension dependent link between E-cadherin and actin, which involves vinculin and associated proteins
J. de Rooij, Q. le Duc and I. Blonk
P055 Targeted deletion of tgm-2 uncovers a role for extracellular transglutaminase-2 in RhoA downregulation during fibroblast adhesion to fibronectin
E.A.M. Verderio, A. Scarpellini, X. Li, D. Telci, T. Muramatsu, G. Melino, R.A. Jones and M. Griffin
P056 The cellular prion protein PrPc is involved in the proliferation of epithelial cells and in the distribution of junction-associated proteins
E. Morel, S. Fouquet, C. Strup-Perrot, C. Pichol, D. Loew, A.M. Faussat, L. Yvernault, M. Pinçon-Raymond, J. Chambaz, M. Rousset, S. Thenet and C. Clair
P057 The structure of the C-terminal actin-binding domain of talin
A.R. Gingras, N. Bate, B.T. Goult, L. Hazelwood, I. Canestrelli, J.G. Grossmann, H. Liu, N.S.M. Putz, G.C.K. Roberts, N. Volkmann, D. Hanein, I.L. Barsukov and D.R. Critchley
P058 Opening up a can of worms: genetic analysis of a-catenin function
N. Harrison and J. Pettitt