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Third intracellular proteolysis meeting. Joint meeting of the INPROTEOLYS network and the Biochemical Society

5—7 March 2008

Auditorio de Tenerife, Santa Cruz de Tenerife, Canary Islands, Spain



5 March 2008

Poster Session 1: 18:00-19:30


P001 The autophagic machinery is necessary for removal of cell corpses during the development of the nervous system.
M. Angeles Mellén, E.J. de la Rosa and P. Boya
P002 E3-independent self-ubiquitination of Ub-binding proteins
D. Hoeller, C.-M. Hecker, S. Wagner and I. Dikic
P003 The proteolytic degradation of RhoB requires palmitoylation of its C-terminal end
K. Stamatakis, M. Herrera, P. Boya and D. Pérez-Sala
P004 Chaperone-mediated autophagy vs. macroautophagy in Golden hamster harderian gland: a gender-related adaptation to different oxidative stress status.
I. Vega-Naredo, B. Caballero, C. Huidobro-Fernández, C. Soria-Valles, D. De Gonzalo-Calvo, D. Tolivia, M.J. Rodríguez-Colunga and A. Coto-Montes
P005 Proteolytic activities are altered in the brain of senescence accelerated mice at 10 months old
B. Caballero, I. Vega-Naredo, V. Sierra, C. Huidobro-Fernández, C. Soria-Valles, D. De Gonzalo-Calvo, D. Tolivia, M.J. Rodríguez-Colunga and A. Coto-Montes
P006 Identification of novel inhibitors of deubiquitinating enzymes
S.J. Goldenberg, J.L. McDermott, T.R. Butt, M.R. Mattern and B. Nicholson
P007 The role of a novel p97/VCP-interacting motif (VIM) in ER-associated degradation
P. Ballar, H. Yang, Y. Shen and S. Fang
P008 CHIP mediated degradation and DNA damage dependent stabilization regulates base excision repair proteins
J.L. Parsons, P.S. Tait, D. Finch, I.I. Dianova, S.L. Allinson and G.L. Dianov
P038 Premature aging in mice activates a pro-survival metabolic response involving autophagy induction
G. Mariño, I. Varela, J. Cadiñanos, J.M.P. Freije and C. López-Otín

6 March 2008

Poster Session 2: 18:00-19:30


P009 Are F-box proteins with a C-terminal domain homologous to the tobacco lectin involved in protein degradation in plants?
N. Lannoo, W.J. Peumans and E.J.M. Van Damme
P010 Ariadne 1b, an E3 ubiquitin-ligase involved in the regulation of esteroid hormone Ecdysone
F. Antonucci and A. Ferrus
P011 Interaction between the Tomato Golden Mosaic Virus replicase and the plant sumoylation pathway
R. Lozano-Durán, M.A. Sanchez-Duran, M.B. Dallas, L. Hanley-Bowdoin and E.R. Bejarano
P012 Coordinated deregulations of Fos-related antigen 1 and -2 proteasomal degradations in cancer cells
J. Basbous, I. Jariel-Encontre, R. Hipskind and M. Piechaczyk
P013 Development of TUBEs (Tandem Ubiquitin Binding Entities) to study ubiquitin dependent processes
R. Hjerpe and M.S. Rodríguez
P014 Probing the ubiquitinome linkage profile
I. Ziv-Uziel, O. Kleifeld, Y. Matiuhin, D.S. Kirkpatrick, W. Kim, S.P. Gygi and M.H. Glickman
P015 Regulation of separase: securin-independent modes of regulating the giant protease that triggers anaphase
D. Boos, A. Holland, C. Kuffer, I. Gorr, B. Mayer, M. Orth, F. Böttger, S.S. Taylor and O. Stemmann
P016 Functional characterization of several structural domains of the deubiquinating enzyme USP25
A. Denuc, A. Bosch, R. Gonzàlez-Duarte and G. Marfany
P017 Impact of intermediate-type proteasomes in viral and tumor antigen presentation
M. Keller, A. Paschen, F. Ebstein, K. Textoris-Taube, E. Krüger, D. Schadendorf, P.-M. Kloetzel and U. Seifert
P018 In vivo biotinylation of neuronal ubiquitin substrates
U. Mayor and A. Brand
P019 The human COP9 signalosome is necessary for SCF-Skp2 stabilization and activity
M.E. Fernandez-Sanchez, E. Sechet, L. Rogge and E. Bianchi
P020 Aggresome formation in response to Ala-Ala-Phe-chloromethylketone is independent of the inhibition of tripeptidyl peptidase II
E.M. Villasevil, S. Guil, C. Sánchez, M. del Val and L.C. Antón
P021 Role of ubiquitin and SUMO molecules in the regulation of the inhibitory function of IkBa on NF-kB activity
V. Lang, F. Aillet, I. Egaña and M. Rodríguez
P022 Regulation of p53 stability and activity by multiple mono ubiquitylation
M. Torres-Ramos, R. Hjerpe, F. Aillet, V. Lang, R. Farràs, R.T. Hay and M.S. Rodríguez
P023 Development of transcription-inactive p53-fusion proteins (TIFp53) as a high-throughput screen system to identify compounds stabilising and promoting p53 tumour suppressor activity
F. Aillet, R. Hjerpe, M. Torres, V. Lang, R. Farràs and M. Rodríguez
P024 Ubiquitin-independent in vitro degradation of nuclear hormone receptors by 20S and 26S proteasome
F. Losada-Urzaiz, B. Alvarez-Castelao and J.G. Castaño
P025 JunB breakdown in G2 is required for proper mitosis
R. Farràs, V. Baldin, S. Gallach, C. Acquaviva, G. Bossis, I. Jariel-Encontre and M. Piechaczyk
P026 SUMO-binding domains are involved in the regulation of tumour suppressors by the Kaposi´s sarcoma-associated herpesvirus latent protein LANA2
L. Marcos-Villar, F. Lopitz, P. Gallego, M. Rodríguez and C. Rivas
P027 SAMe-deficient tumor hepatocyte cell line (SAM-D) shows wild type and active p53 together with UV resistance.
N. Martinez-Lopez, M. Varela-Rey, D. Fernandez-Ramos, U. Ariz, M. Vazquez-Chantada, L. Gomez-Santos, B. Rodriguez, N. Embade, R. Matthiesen, M.S. Rodríguez, J.M. Mato and M.L. Martinez-Chantar

7 March 2008

Poster Session 3: 18:00-19:30


P028 Drosophila transcriptional adaptor Ada3 as a target for SUMOylation in vivo
B. Grau and A. Ferrús
P029 The role of Sumoylation during Drosophila metamorphosis
A. Talamillo, J. Sánchez, R. Cantera, C. Pérez, D. Martín, F. Lopitz, M. Rodríguez and R. Barrio
P030 Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes
G. Bossis, D. Tempe, F. Melchior and M. Piechaczyk
P031 Changes in proteasome functionality induced by wheat sprout extracts
L. Bonfili, V. Cecarini, M. Amici, M. Angeletti, E. Fioretti, R. Tacconi and A.M. Eleuteri
P032 Scaled-down purification of 20S proteasome from human tissue sample: application on normal and tumor colorectal cells
S. Uttenweiler-Joseph, M. Ducoux-Petit, F. Brichory, M.P. Bousquet-Dubouch, O. Burlet-Schiltz, J.-F. Haeuw and B. Monsarrat
P033 Remodeling of the ubiquitin proteasome system in response to Interferons
U. Seifert*, L. Bialy*, D. Bech-Otschir, F. Ebstein, M. Rieger, U. Kuckelkorn, P.-M. Kloetzel and E. Krüger
P035 A novel affinity-based purification procedure of human proteasome complexes and proteasome interacting proteins
M.-P. Bousquet-Dubouch, E. Baudelet, F. Guérin, M. Matondo, S. Uttenweiler-Joseph, O. Burlet-Schiltz and B. Monsarrat
P036 Amyloid peptides in different assembly states and related effects on isolated and cellular proteasomes
V. Cecarini, L. Bonfili, M. Amici, M. Angeletti, A.M. Eleuteri
P037 Docking analysis applied to the interaction between polyphenols and mammalian 20S proteasome
M. Mozzicafreddo, M. Cuccioloni, L. Bonfili, V. Cecarini, A.M. Eleuteri and M. Angeletti