A Biochemical Society Focused Meeting
Abstract deadline: 17 July 2017.
Abstract submission is now open
Early bird registration deadline: 17 July 2017.
Registration is now open
‘Exosomes and Microvesicles: roles in disease pathology and therapy,’ will focus on the considerable roles EMVs play in disease progression and pathology, including subversion of the immune system. The focused meeting aims to bring key workers in the EMV field together, to use recent basic EMV research to enhance translational efforts as the EMV field moves into therapeutic research.
Much of this work is still at the cellular, in vitro level but the meeting will also showcase the role of EMVs at the organismal level in relevant mouse models and clinical studies The meeting will also address infectious agents and the role of their released vesicles in the infection process including as decoys for innate immune effector mechanisms. The role of host MVs in the invasive process, through MV-bourne cytokine signalling will also be considered. Furthermore, EMVs play a plethora of roles in disease progression, such as fibrosis, through their contribution to Epithelial-Mesenchymal-Transition and angiogenesis, as well as in autoimmune disease.
The meeting topic will be of interest to researchers across a wide range of subjects within biomedicine because the mechanisms by which EMVs promote cellular dysfunction and disease are being found to be shared by a range of illnesses, including infectious, autoimmune, neurodegenerative as well as in cancer.
The second main focus of this meeting will be the development of EMVs in therapy either as drug delivery vehicles, for example carrying siRNA, or the use of stem cell MVs to repair acute organ injury or even the specific immuno-depletion of EMVs. Research into the use of EMVs as therapeutic vehicles, benefiting from being completely non-immunostimulatory, in the forthcoming era of personalised drug delivery, is sure to become a massive area of interest.
Jameel Inal (London Metropolitan University, UK)
Sheelagh Heugh (London Metropolitan University, UK)
Una Fairbrother (London Metropolitan University, UK)
Oral communication slots are available at this meeting.
All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.
Grants and Bursaries
The Biochemical Society offers a programme of grants and bursaries supporting research, attendance at scientific conferences and the sponsorship of events.
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Topics in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.