Earlybird registration deadline: 28 June 2019
Abstract submission deadline: 28 June 2019
Over the last ~5 years, cryo-electron microscopy single-particle reconstruction and tomography have resulted in an extraordinary amount of structural information of respiratory membrane complexes, the value of which is yet to be fully explored. Even more recently, the importance of membrane protein dynamics, formation of supercomplexes and organisation within microbial (inner membrane) or mitochondrial cristae has been highlighted. These new insights have shaken the classical view of respiratory chains. An interdisciplinary evaluation of these results with experts from neighbouring fields such as protein-protein interactions, computational biology, dynamic membrane transport mechanisms and lipid biophysics is now needed to retain and even accelerate this momentum. Translation to the clinical sciences or an enhanced understanding of the structural dynamics for the functional properties of respiration and transport can also provide an opportunity to open up new fields of research.
The programme is designed to bring leaders in the fields of molecular respiration together with scientists working at the forefront of membrane transport, membrane structural biology and lipid biochemistry to create a more complete understanding of respiration and transport and explore further the relationship between function and disease.
The application of advanced biophysical techniques to such systems is at the forefront of both method and research developments and new technologies could further revolutionise our understanding of membrane bioenergetics. The residential format of the Harden conference, widely known for its emphasis on free and open discussion, will encourage the exchange of the latest data and a critical discussion of the technical challenges that these developments face.
- Complexes and supercomplexes: new perspectives on respiratory chains
- Membrane organisation
- Membrane transport and regulation
- Protein-protein interactions and lipids
- Emerging hot topics
- Bioenergetics and drug targets
- Fraser MacMillan, University of East Anglia, UK
- Amandine Maréchal, University College London / Birkbeck, UK
- Lars Jeuken, University of Leeds, UK
Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.
Unique to the Biochemical Society, Harden Conferences are residential research conferences covering a specialist topic.
The conferences bring together scientists from various backgrounds with a common interest in - but varying approaches to - the topic of the conference.
To maintain a suitably high level of discussion and presentation at the conference, it is desirable that participants be experienced in the field covered; most of the participants will be expected to have postdoctoral or equivalent experience, although Ph.D. students will also be welcome.
The planned scientific sessions feature speakers invited by the Organizers and, in addition, time is left for extensive discussion and for short contributions, including posters, by other conference participants.
All participants must be resident for the duration of the conference.
Bursaries and free places
A limited number of bursaries to cover the cost of registration are available to assist younger members of the Biochemical Society to attend the conferences.
Preference will be given to senior graduate students (or those who gained their Ph.D. in the last 5 years) and restricted to members of the Biochemical Society.
Applications for these places should be sent to the Biochemical Society from the applicant's supervisor and should be accompanied by an independent reference.
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