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Future Events > Deubiquitinases - from structure to physiology

Sponsored by:

Deubiquitinases - from structure to physiology

26—28 June 2017

St Hugh's College, Oxford



A Biochemical Society Focused Meeting

 

Abstract deadline: Abstract submission is now closed.

 

Registration has now closed.

 

Deubiquitinases (DUBs) are key components of the ubiquitin system, and play major roles in important physiological processes, in particular in protein turnover and cell signalling. Indeed, ubiquitin modifications can take many forms: in addition to single modification (monoubiquitination), ubiquitin can form polymers through eight distinct linkage points (polyubiquitination), and ubiquitin can also cross-talk with other posttranslational modifications such as phosphorylation and ubiquitin-like modifications. DUBs tackle this complex protein modification system in a highly sophisticated manner. 

Recent years have seen great progress in assigning specific DUBs to biological pathways and in understanding the structural underpinning of their activity, specificity and regulation. Moreover, DUBs are emerging as a novel class of druggable targets in cancer, neurodegeneration, infection and inflammation. This conference will provide the first international meeting dedicated to this class of enzymes, encompassing structural, physiological and translational aspects. It will bring together international leaders in the field together with early stage researchers, in a setting and atmosphere aimed at fostering collegiality and collaboration. In addition to invited speakers, a number of talks will be selected from the submitted abstracts.

Oral communication slots are available at this meeting. 

All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication.

 

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Publishing

Topics in this meeting may be invited to submit to our journal, Biochemical Society Transactions, or other publication published by Portland Press, the wholly-owned trading subsidiary of the Biochemical Society.