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Systems Biology: Will it Work?

12—14 January 2005

University of Sheffield, UK



Wednesday 12 January 2005
17:00 - 18:00 Registration

17:30 - 18:30 Dinner

19:00 - 19:20
Welcome and introduction
Mike Williamson (Sheffield, UK)
19:20 - 20:00
The role of feedback in the control and regulation of intracellular networks: a dynamic systems approach
Olaf Wolkenhauer (Rostock, Germany)
20:00 - 20:40
Systems biology may work when we learn to understand the parts in terms of the whole
Athel Cornish-Bowden (CNRS-BIP, Marseille, France)
20:40 - 21:00 General Discussion

Thursday 13 January 2005
09:00 - 09:40
Metabolomics, machine learning and modelling: towards an understanding of the language of cells
Douglas Kell (UMIST, UK)
09:40 - 10:20
Global systems biology: understanding the mammalian superorganism in health and disease via Metabonomics
Jeremy Nicholson (Imperial College London, UK)
10:20 - 10:35 General discussion

10:35 - 11:00 Coffee / tea break

11:00 - 11:40
Mitochondrial complex I: a biological energy transducer
Judy Hirst (MRC-Dunn Human Nutrition Unit, Cambridge, UK)
11:40 - 12:20
Evolution of protein interactions in complexes and networks
Sarah Teichmann (MRC-LMB, Cambridge, UK)
12:20 - 12:35 General discussion

12:35 - 14:00 Lunch

14:00 - 14:40
Towards systematic biology in the mammalian nervous system
Jyoti Choudhary - The British Biophysical Society Lecture (Cambridge, UK)
14:40 - 15:20
Algorithms for protein interaction networks
Liisa Holm (Helsinki, Finland)
15:20 - 15:35 General discussion

15:35 - 16:00 Coffee / tea break

16:00 - 16:15
BBSRC systems biology centres: update on progress
Alf Game (BBSRC, UK)
16:15 - 16:55
The proteome as a dynamic entity - is yesterdays proteome the same as todays?
Rob Beynon (Liverpool, UK)
16:55 - 17:35
A systems approach to subcellular location
Bob Murphy (Carnegie Mellon, Pittsburgh, PA, USA)
17:35 - 17:50 General discussion

17:50 - 19:00 Drinks reception and poster session

19:45 - 21:30 Conference Dinner

Friday 14 January 2005
09:00 - 09:40
The heart is already working
Denis Noble (Oxford, UK)
09:40 - 10:00
Towards a virtual outer membrane: from simulations to systems
Selected oral communication - Syma Khalid (Oxford, UK)
10:00 - 10:20
Biology of ageing e-Science integration and simulation
Selected oral communication - Daryl Shanley (Newcastle, UK)
10:20 - 10:35 General discussion

10:35 - 11:00 Coffee / tea break

11:00 - 11:40
Yes!
Hans Westerhoff (Amsterdam, The Netherlands)
11:40 - 12:20
Fashion in science: a plethora of ¿-omics¿ to systems biology
Walter Blackstock (Sheffield, UK)
12:20 - 12:45 General discussion

12:45 Lunch and departure