2018 Industry and Academic Collaboration Award Lecture: Validating disease targets using open access chemical probes

The inaugural Industry and Academic Collaboration Award was awarded in 2018 to Stefan Knapp from the Institute of Pharmaceutical Chemistry, the Buchmann Institute for Molecular Life Sciences at Frankfurt University as well as at the Structural Genomics Consortium at Oxford University.

His research team made a major contribution to the understanding of structural mechanisms regulating signalling molecules such as protein kinases, phosphatases, acetylation dependent reader domains of the bromodomain family and the exploitation of this knowledge for the development of highly specific inhibitors. In the framework of a large collaborative network involving many academic research groups and industry, he pioneered the development of protein interaction inhibitors targeting bromodomains that function as lysine acetylation dependent reader domains of the epigenetic code as well as highly specific allosteric inhibitors modulating kinase function.

The lecture, entitled ‘Validating disease targets using open access chemical probes’ took place at the Brighton and Sussex Medical School Teaching Building, University of Sussex, UK.

Programme:

16:00-17:00 Award presentation and lecture: Validating disease targets using open access chemical probe

17:00-18:00 Drinks reception

Date

Dec 10 2018

Location

Brighton and Sussex Medical School Teaching Building
Sussex University, UK
Biochemical Society

Organiser

Biochemical Society
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