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The biology and pathology of Tau and its role in tauopathies II

8—9 January 2012

Robinson College, Cambridge, UK

Poster Session

8 January 2012 18:45 - 20:00

P001 Are tau oligomers protective?
Catherine M Cowan, Sarah Hands, Megan A Sealey, Douglas W Allan, Amritpal Mudher
P002 Physiology and pathology of Tau as studied by NMR
Guy Lippens
P003 Tau-dependent neuronal toxicity in vivo can be directly correlated with its phosphorylation at Ser238
Katerina Papanikolopoulou, Efthimios Skoulakis
P004 Stress, Amyloid-ß and Tau: the triangle of oblivion
Ioannis Sotiropoulos, Joana Silva, Osborne F Almeida, Nuno Sousa
P005 Novel fluorescent probes for spectral assignment of tau aggregates
Therése Klingstedt, Cristiane Blechschmidt, Anna Nogalska, Stefan Prokop, Frank L. Heppner, W. King Engel, Valerie Askanas, K.Peter R. Nilsson
P006 Investigating the role of Caspase-3 and Caspase-6 in the generation of conformationally-changed tau
Joanna Wolak, Lucy Hamilton, Dimitra Kestoras, Peter Davies, Michael Hutton, Philip G Szekeres
P007 Correlations between cortical and subcortical tau pathology
Johannes Attems, Alan J Thomas, Kurt A Jellinger
P008 Altered intrinsic excitability and resonant properties in a mouse model of tauoapthy
Clair Booth, Jon Brown, Andrew Randall
P009 Expression of 3R and 4R human tau isoforms gives rise to different phenotypes in Drosophila
Megan Sealey, Catherine M Cowan, Shmma Quraishe, Efthimios Skoulakis, Amritpal Mudher
P010 Stress kinases – linking AD pathology to proteasome dysfunction
Lotta Agholme, Sangeeta Nath, Katarina Kågedal, Jan Marcusson, Martin Hallbeck
P011 Paracetamol (PA) and the causation of Fischer-Alzheimer's disease (F-AD): a suggested sequence of events
Robert Jones
P012 Does replication have a physiopathology role in Drosophila models of Alzheimer disease ?
Sylvina Bouleau, Anita Reinhardt, Véronique Monnier, Herve Tricoire
P013 ApoE effect on biomarkers of amyloidogenesis, tau pathology and neurodegeneration in Alzheimer Disease.
Valerio Leoni, Claudio Caccia
P014 Chronic inhibition of the MEK/ERK pathway fails to delay disease progression in a transgenic animal model of tauopathy
Annalisa Cavallini, Tracey K Murray, Lisa Baschirotto, Dan L Czilli, Claire V Cella, Mark A Ward, Jenna Hanmer, Helen Sims, Elizabeth Eberle, Aaron Simmons, Sandra M Sossick, Jeffrey W Cramer, David O Calligaro, Ana I Mateo, Laura J Bloem, Hugh Nuthall, Michael J O'Neill, Peter Davies, Michel Goedert, Michael Hutton, Philip G Szekeres, Suchira Bose
P015 AMPK modulates Tau-dependent toxicity in the Drosophila eye.
Alessia Galasso Jr., Charles Cameron, Quentin Caudron, John Aston, Calum Sutherland, Bruno Frenguelli, Kevin Moffat
P016 Normal and pathological function of Tau in Drosophila melanogaster
Marie-Laure PARMENTIER, Yasmina TALMAT-AMAR, Bénédicte FRANCO, Yoan ARRIBAT, Sébastien FEUILLETTE, Christelle Redt-Clouet, Anne-Laure BOUGE, Magalie LECOURTOIS
P017 A recessive clonal screen in Drosophila identifies mitotic spindle genes as modifiers of tau toxicity
Marc Gistelinck, Patrick Callaerts, Bart Dermaut
P018 A detailed longitudinal assessment of pathology in male and female rTg4510 tau transgenic mice.
Katya Malfa, Claire V Cella, Hannah Clarke, Mark A Ward, Dan L Czilli, Tracey K Murray, Michael L Hutton, Michael J O'Neill
P019 Tau phosphorylation state differentially influences its degradation
Teresa Rodriguez Martin, Inmaculada Cuchillo-Ibanez, Diane Hanger
P020 Phosphorylation-induced structural changes in Repeat 1 of the tau microtubule binding domain
Martin Schwalbe, Stefan Bibow, Jacek Biernat, Eckhard Mandelkow
P021 Tau Protein: Enhancement and Inhibition of Aggregation
Elias Akoury, Marcus Pickhardt, Jacek Biernat, Eckhard Mandelkow, Markus Zweckstetter
P022 IL-1ß is involved in Tau expression and phosphorylation in differentiated SH-SY5Y cells
Montaña Caballero Bermejo, Marta Olivera Santa-Catalina, Juan Carlos Alonso, Ricardo Argent, Francisco Centeno, Maria Jesus Lorenzo
P023 Functional analysis of the MAPT promoter haplotypes.
Tara Caffrey, Franziska Denk, Richard Wade-Martins
P024 Phosphorylation regulates the association of tau with neuronal membranes and the tyrosine kinase fyn
Amy M Pooler, Alessia Usardi, Wendy Noble, Diane Hanger
P025 Characterisation of a BAC-based transgenic mouse model of tauopathy
Heike J Wobst, Tonya N Taylor, David Bannerman, Mariana Vargas-Caballero, Sara J Johnson, Richard Wade-Martins
P026 Dopaminergic signaling in a novel tau transgenic mouse model: MAPT-ing a new road to Parkinson’s disease
Sara J Johnson, Sarah Threfell, Stephanie J Cragg, Richard Wade-Martins
P027 Does telomerase have a protective role in neurons against Tau?
Rafal Czapiewski, Simon Gutbier, Chatchawan Singhapol, Hannah Rosa, Ros Hall, Johannes Attems, Gabriele C Saretzki
P028 Endoplasmic stress, tau phosphorylation and aggregation
Anna Nolle, Diana A Nijholt, Rob Zwart, Wiep Scheper
P029 Amyloid precursor protein regulates tau phosphorylation
Daniela Passarella, Mario Nizzari, Valentina Caorsi, Alberto Diaspro, Federica Cocco, Tullio Florio, Claudio Russo
P030 Hyperphosphorylation and glycosylation induce opposing structural effects in tau
Michael A Brister, Agata A Bielska, Neal J Zondlo
P031 Identification of proteins that form complexes with tau in mouse brain.
Ilse Dewachter, Gerard Joberty, Bart Dermaut, Marc Vandermeeren, Bernadette Tasiaux, Arjan Buist, Jean-Noël Octave, Marc Mercken, Dieder Moechars
P032 Investigating the progression of tauopathy with the use of novel Tau antibodies in an inducible mouse model
Sarah M Ward, Yifan Fu, Sarah Satter, Naruhiko Sahara, Kristina R Patterson, Nicholas M Kanaan, Lester I Binder
P033 Astrocytes: a key component of the amyloid cascade?
Claire J Garwood, Amy M Pooler, Diane Hanger, Wendy Noble
P034 Understanding tau splicing in disease using post-mortem brain tissue and patient-derived cell models
Selina Wray, Mina Ryten, Daniah Trabzuni, Jana Vandrovcova, Colin Mahoney, Rohan de Silva, Tilo Kunath, Martin Rossor, John Hardy
P035 Can microtubule stabilising agents protect against neuronal dysfunction in a Drosophila model of tauopathy?
Shmma Quraishe, Catherine M Cowan, Amritpal Mudher
P036 Expression of WldS delays neurodegeneration in Drosophila models of acute injury and tauopathy
Tracey A Newman, Hassan Shaibah, Katy Stubbs, Victor H Perry, Amritpal Mudher, David Shepherd
P037 Neuroprotection effects of potential anti-aggregation small molecule inhibitors.
Cornelia M Wilson