13-15 September 2023
Gran Hotel Rey Don Jaime, Castelldefels, Barcelona, Spain

Abstract & early booking deadlines: 13 July 2023.

This meeting will cover the broader PI3K pathway, including basic research in signalling and biology, the generation of improved pharmacological pathway modulators, and their use in cancer, immunity and rare diseases.

A better understanding of the clinical observations using PI3K pathway inhibitors – alongside progress in the pharmacological targeting of these enzymes, such as mutant-selective inhibitors, effective AKT inhibitors, and PI3K activators – is heralding a new phase of research and clinical development. Basic science investigations also continue to provide new insight into the pathway and the clinical observations, opening new opportunities for drug re-positioning. Together, these developments have created renewed interest in the field, which we are aiming to capture with this meeting.

Programme Coordinators:

• Mariona Graupera 
• Sigrid Skånland 
• Klaus Okkenhaug 
• Bart Vanhaesebroeck 

Topics include: 

• Class I/II/III PI3K signalling and biology
• AKT – mTOR signalling and biology
• Structural insights into PI3K regulation
• New pharmacological developments: PIK3CA-mutant selective inhibitors, PI3K activators
• Rare diseases and PI3K pathway deregulation: PROS – APDS – PHTS – TSC
• Progress on clinical development in rare diseases, sporadic cancer, and cancer prevention
• Discussion sessions: ‘Rational understanding of PI3K pathway inhibitor toxicities’ and ‘How to measure PI3K pathway activation in cells and tissues?

Oral communication slots are available at this meeting. All attendees, particularly researchers in the early stages of their career, are invited to submit a poster abstract for consideration as an oral communication. You can submit your abstract here.

This event is sponsored by:

Sponsorship opportunities are available for this meeting. For more details and to find out how you can get involved, please contact Hannah Atkins, Sponsorship Manager.

Biochemical Society Bursaries

We offer a wide variety of grants and bursaries to help you attend this event and save money on registration fees! Support is available to cover registration, accessibility, companion costs and more.

Apply during the registration process for any of the following schemes:

• Full and Early Career Bursaries
  
• Student Bursaries
• General Travel Grants
• Care and Assistance Grants
  
• Stay Connected Bursaries

Not a member of the Biochemical Society? Join today and save up to £100 on your registration fee.