Our latest ECR webinar explored the use of native mass spectrometry to unravel the activity and regulation of the molecular chaperone BiP, as well as the crucial role of Ribosome-associated Quality Control in mitigating the cytotoxic effects of chemotherapy drugs.

Throughout the two presentations, John discussed the use of native mass spectrometry – an emerging technology for characterizing interactions between proteins and small molecules in unprecedented detail – to probe interactions between BiP, various nucleotides, and calcium and Susanta's presentation revealed a potential role for Ribosome Quality Control Pathways in mitigating the cytotoxic effects of 5FU.

Speakers:

• John Young, University of Oxford, UK
• Susanta Chatterjee, Queen’s University Belfast, UK

This webinar was chaired by Dr Katya Lamber, Kingston Uni.