Date and Time: TBC - September/October 2027

Location: UK

Bacterial cells are among the smallest forms of life, and their diminutive size demands exceptional sensitivity and spatial resolution to probe their inner workings at the molecular scale. Single-molecule imaging has transformed our ability to study the processes that drive bacterial life. Advances in fluorescent probes, ultrasensitive microscopy, microfluidics, and image analysis now allow us to observe reactions, interactions, and dynamics within individual cells in real time. In this sense, we are rediscovering bacteria through an entirely new lens.

Single-Molecule Bacteriology 4 continues a series launched in 2018 and expanded through successful meetings in 2021 and 2024, reflecting both the rapid evolution of the field and the strength of its community. This fourth meeting brings together cutting-edge developments across the discipline—from super-resolution imaging and single-molecule structural approaches to quantitative in vivo methods, machine learning, and complementary theoretical frameworks. The meeting will also highlight work with direct clinical and translational relevance, including advances in understanding antibiotic resistance. New this year are dedicated interactive sessions designed to foster collaboration, networking, and training, ensuring that the meeting serves not only as a showcase of leading science but also as a platform for community building and growth.