In the first webinar of our dedicated ECR (Early Career Researcher) series, we provided the opportunity for Jack and Cian – both early career researchers – to share their work on inflammasomes and plant resistosome.

The plant resistosome and the inflammasome share important similarities, reflecting the importance of studies in different kingdoms and how this can lead to new and very important discoveries. Plants and animals detect and respond to pathogens with intracellular nucleotide-binding leucine rich repeat (NLR) immune receptors. Plant NLRs often co-operate as pairs or networks, with “sensors NLRs” responsible for detecting the pathogen and “helper NLRs” executing downstream immune responses which typically culminate in programmed cell death.

Invited speakers:

• Jack Green, Presidential Fellow at the University of Manchester
• Cian Duggan, Schrödinger Scholar at Imperial College London

This webinar was chaired by Gloria Lopez-Castejon, a Wellcome Trust and Royal Society Sir Henry Dale Research Fellow at the Lydia Becker Institute of Immunology and inflammation (University of Manchester), and a member of the Biochemical Society’s Research Area IV – Cells.