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Research Area I - Genes
...Research Area I covers the broad areas of DNA synthesis, repair, recombination and replication; RNA transcription, processing, translation, localisation and stability; genomics; chromosomes structure and dynamics; non-coding RNA; nucleic acid binding proteins; mutation; gene expression; epigenetics.
...Our factsheets provide an introduction to important topics in molecular bioscience, designed to support the teaching of these topics and for anyone with an interest in current developments in molecular bioscience.
Alpha-synuclein, a central player in neurodegenerative diseases
...In this webinar, we heard from the 2020 Thudichum Medal recipient, Professor Maria Grazia Spillantini. With her collaborators, Maria Grazia identified alpha-synuclein as the major component of the filaments that form the Lewy bodies in Parkinson’s disease and dementia with Lewy bodies, and described one of the first mutations in the Tau gene leading to frontotemporal dementia and Parkinsonism linked to chromosome 17.